LC/MS Analysis of Antipsychotic Drugs on Ascentis® Express RP Amide

LC/MS Analysis of Antipsychotic Drugs on Ascentis® Express RP Amide

Conditions

column Ascentis Express RP Amide, 10 cm x 2.1 mm I.D., 2.7 µm particles (53913-U)
column temp. 35 °C
mobile phase [A] 5 mM ammonium formate water; [B] 5mM ammonium formate in 95:5 (v/v) methanol:water
gradient held at 35% B for 0.5 min; 35 to 85% B in 5.5 min; held at 85% B for 1 min
flow rate 0.3 mL/min
pressure 4641 psi (320 bar)
sample 200 ng/mL in waler
injection 1 µL
detector ESI(+), m/z 100-1000

Description

Categories Analytical Chromatography, Clinical, antipsychotics, Antipsychotics
Featured Industry Clinical
Pharmaceutical (small molecule)
Legal Information Ascentis is a registered trademark of Sigma-Aldrich Co. LLC
suitability application for HPLC

Materials

     
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