LC/MS/MS Analysis of Polymeric Isocyanates as Their HDI-DBA and IPDI-DBA Derivatives on Ascentis® Express C18

LC/MS/MS Analysis of Polymeric Isocyanates as Their HDI-DBA and IPDI-DBA Derivatives on Ascentis® Express C18

Conditions

sample preparation SPE (Solid Phase Extraction)
sample/matrix air
adsorbent tube ASSET EZ4-NCO Dry Sampler (5028-U)
extraction Contact Sigma-Aldrich Technical Services for extraction and full analytical protocol
column Ascentis Express C18, 5 cm x 2.1 mm I.D., 2 µm particles (50811-U)
column temp. 35 °C
mobile phase [A] 95:5 (0.05% formic acid in water):(0.05% formic acid in acetonitrile); [B] 95:5 (0.05% formic acid in acetonitrile):(0.05% formic acid in water
gradient 60 to 80% B in 2 min, hold for 3 min, to 100% B in 0.1 min, hold for 9.9 min, to 60% B in 0.1 min, hold for 3.9 mi
flow rate 0.4 mL/min
pressure 3626 psi (250 bar)
injection 2.0 µL
detector MS/MS, ESI(+), MRM

Description

Analysis Note This application demonstrates the siµLtaneous analysis of dibutylamine derivatized isocyanate HDI & IPDI monomers and oligomers on Ascentis Express columns.
Categories Analytical Chromatography, Air Monitoring Applications, Isocyanates
Featured Industry Industrial Hygiene
Legal Information Ascentis is a registered trademark of Sigma-Aldrich Co. LLC
Other Notes sample pretreatment: Samples were collected during a spray-painting application
suitability application for LC-MS

Materials

     
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