UHPLC/MS Analysis of Heroin and Related Compounds on Titan™ C18

UHPLC/MS Analysis of Heroin and Related Compounds on Titan™ C18

Conditions

column Titan C18 5 cm x 2.1 mm I.D., 1.9 µm particles (577122-U)
column temp. 35 °C
mobile phase [A] 5 mM ammonium acetate in 95:5, water:acetonitrile; [B] 5 mM ammonium acetate in 5:95, water:acetonitrile
gradient 0 to 100% B in 3 min, held at 100% B for 1 min
flow rate 0.6 mL/min
pressure 6770 psi (467 bar)
sample 1 µg/mL in 95:5, water:methanol
injection 0.5 µL
detector MS-TOF, XIC

Description

Analysis Note This method shows heroin and related compounds separated on a Titan C18 column and MS detection. The highest quality LC-MS solvents were used to supply low background interference and low particulate contaminants for robust, trouble-free operation. Cerilliant CRMs provided reliable identification and quantification.
Categories Analytical Chromatography, Forensics and Toxicology, Pharmaceutical Analysis, antiepileptic/antiseizure, Anticonvulsant/antiepiletic/antiseizure, Drugs of Abuse, drugs of abuse
Featured Industry Forensics and Toxicology
Legal Information Titan is a trademark of Sigma-Aldrich Co. LLC
suitability application for UHPLC

Materials

     
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