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Amicon® Pro Purification System

The Amicon Pro centrifugal protein purification system, which combines an affinity-based spin column with an Amicon Ultra 0.5 mL filter, enables you to purify, concentration, and exchange the buffer of your protein sample, all in the same, versatile device. No need to transfer the sample, no risk of protein loss.
 

 

 

 

Application Highlights of Amicon Pro Method
Affinity purification (all-in-one binding, washing, elution, concentration) 1 hour, 4 spins, <10 mL samples
Buffer exchange/desalting/dialysis 20 minutes, 1 spin
Concentration of protein 25X concentration
Serum depletion 2 steps to remove
Antibody labeling and cleanup 1 hour, 3 spins

 

Continuous buffer exchange enables 1,000-fold (99.99%) desalting while maintaining protein integrity. It’s a gentler way to purify high yields of biologically active, pure protein, thanks to the clever design of the Amicon Pro exchange device and tip.

All-in-one Protein Purification Using the Amicon Pro System

Watch this short video to understand how the Amicon Pro system works:
 

Ordering Information

Product No. Millipore Catalog No. Name MWCO Volume Minimal Final Concentrate Volume Sterility Pack Size Add to Cart
ACS510002 ACS510002 Amicon Pro Purification System 100K 10 mL 15 µL Non-Sterile 2 pack
ACS5100 ACS510012 Amicon Pro Purification System 100K 10 mL 15 µL Non-Sterile 12 pack
ACS501002 ACS501002 Amicon Pro Purification System 10K 10 mL 15 µL Non-Sterile 2 pack
ACS5010 ACS501012 Amicon Pro Purification System 10K 10 mL 15 µL Non-Sterile 12 pack
ACS503002 ACS503002 Amicon Pro Purification System 30K 10 mL 15 µL Non-Sterile 2 pack
ACS5030 ACS503012 Amicon Pro Purification System 30K 10 mL 15 µL Non-Sterile 12 pack
ACS500302 ACS500302 Amicon Pro Purification System 3K 10 mL 15 µL Non-Sterile 2 pack
ACS5003 ACS500312 Amicon Pro Purification System 3K 10 mL 15 µL Non-Sterile 12 pack
ACS505002 ACS505002 Amicon Pro Purification System 50K 10 mL 15 µL Non-Sterile 2 pack
ACS5050 ACS505012 Amicon Pro Purification System 50K 10 mL 15 µL Non-Sterile 12 pack