Certain features of will be down for maintenance the evening of Friday August 18th starting at 8:00 pm CDT until Saturday August 19th at 12:01 pm CDT.   Please note that you still have telephone and email access to our local offices. We apologize for any inconvenience.

Natural Amino Acid Building Blocks for Peptide Synthesis

By: Matthias Junkers, Aldrich ChemFiles 2008, 8.7, 22.

Aldrich ChemFiles 2008, 8.7, 22.

With a growing peptide drug market the fast, reliable and uncomplicated synthesis of peptides is of paramount importance.1 Today, the most common synthetic approaches to medium and even large peptides follow the Boc/Bzl or Fmoc/tBu solid phase peptide synthesis strategies.2 A convenient list of the most popular Boc- and Fmoc-protected amino acid building blocks for these two synthesis strategies can be found in this issue. The Boc-protected amino acids are also frequently used in solution phase peptide synthesis procedures.

back to top Back to Top




  1. Marx, V. C&E News 2005, 83, 17.
  2. Houben-Weyl, Methods of Organic Chemistry, “Synthesis of Peptides and Peptidomimetics”, Thieme 2001, add. and suppl.vol. to the 4th ed. Vol E 22 a.

back to top Back to Top

Related Links