Pd(0) EnCat™ 30NP

Aldrich ChemFiles 2006, 6.6, 13.

Aldrich ChemFiles 2006, 6.6, 13.

Highly Versatile Catalyst for Chemoselective Hydrogenations

  • Safe and nonpyrophoric
  • Trivial removal of catalyst from reactor
  • Very low metal contamination of product
  • Excellent catalyst recyclability
  • Highly chemoselective under both hydrogenation & transfer hydrogenation conditions
  • Excellent batch-to-batch reproducibility of catalyst activity

Pd(0) EnCat™ 30NP is a new microencapsulated hydrogenation catalyst offering key advantages over existing heterogeneous hydrogenation catalysts. Reductive transformations catalyzed by Pd(0) EnCat™ 30NP include aryl ketones, aldehydes, and epoxides to the corresponding alcohols; nitroarenes and aryl nitriles to the corresponding amines; alkenes and alkynes to the corresponding alkanes; and the debenzylation of aryl benzyl ethers.

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Materials

     

References

  1. Bremeyer, N.; Ley, S. V.; Ramarao, C.; Shirley, I. M.; Smith, S. C. Synlett 2002, 1843.
  2. (a) Yu, J.-Q.; Wu, H.-C.; Ramarao, C.; Spencer, J. B.; Ley, S. V. Chem. Commun. 2003, 678. (b) Ley, S. V.; Mitchell, C.; Pears, D.; Ramarao, C.; Yu, J.-Q.; Zhou, W. Org. Lett. 2003, 5, 4665.

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