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TentaGel® S Trt Resins Preloaded with N-Terminal Free Amino Acids

ChemFiles Volume 3 Article 4


Preloaded TentaGel® S Trt resin consists of Fmoc-amino acids attached to highly acid-labile 4-carboxytrityl resin.(1-3) TentaGel® S Trt is derived from TentaGel® S NH2 by acylation with 4-carboxytrityl handle. For detailed information about applications, attachment of the C-terminal amino acid and cleavage condition, please look at the references cited for 2-chlorotrityl chloride resin. The polymer matrix of TentaGel® S PHB resin is PEG grafted on low cross-linked PS beads.

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Materials

     

References

  1. Bayer E. et al. Peptides, Chemistry, Structure and Biology, Proc. 13th Am. Pept. Symp., Hodges, R. S., Smith, J. A., Eds: ESCOM, Leiden 1994; p. 156
  2. Grübler G. et al. Innovations and Perspectives in solid-phase Synthesis, 3rd International Symposium, (R. Epton, ed.), Mayflower Worldwide, Birmingham 1994; p. 517.
  3. Henkel, B. et al. Z. Naturforsch B, 1996, 51, 1339.

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