Bing-Feng Shi Group – Professor Product Portal

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Professor Bing-Feng Shi

The major research interests of Prof. Bing-Feng Shi's lab are focused on transition metal-catalyzed transformations and their application in the synthesis of natural products. Recently, his group has developed the direct functionalization of C(sp3)-H bonds, especially the chemically inactive methylene C(sp3)-H bonds assisted by PIP-auxiliary. Currently, the Shi lab is continuing its work on the development of new reactions and auxiliaries for C-H bond functionalization.

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Qi Zhang et. al
Angewandte Chemie (International Edition), 52(51), 13588-13592 (2013)
Give Me an Ar, give Me an N! Arylation of the methyl group in a simple derivative of readily available alanine under palladium catalysis was followed by intramolecular amidation at the same position to give chiral α-amino-β-lactams with a wide range...Read More