High-Purity Monomers & Polymers for Ophthalmic Applications



 

The development and manufacture of contact and intraocular lenses relies on innovative, high-quality polymers and reagents. New materials can help enhance oxygen and water permeability, providing increased comfort and safety to contact lens wearers.

Monomer selection impacts a number of lens attributes such as modulus, permeability, surface smoothness, UV radiation absorption and resistance to tearing and surface defects.

Sigma-Aldrich® offers a continuously expanding selection of high-purity monomers and polymers for ophthalmic applications, along with a full range of initiators, crosslinkers, dyes, and solvents.

Our broad selection, high quality and outstanding service enable contact lens manufacturers to quickly and successfully develop revolutionary new products.

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From Research to Commercial Scale Manufacturing – Your Monomer Expert

If a monomer of interest is not on this product list, or if you have a unique requirement, we invite you to take advantage of our extensive custom manufacturing capabilities. Our state-of-the-art facilities enable us to provide customized support from process development through scale-up and production. We offer a variety of services including multi-step organic synthesis, handling of air-sensitive compounds and high-efficiency flow chemistry. Whatever your specific needs may be, your manufacturing program will be managed by experienced project teams that will ensure timely and cost-effective completion.

Examples of specialty monomers on manufacturing scale:

  • 3-[Tris(trimethylsiloxy)silyl]propyl vinyl carbamate
  • 3-(Trimethoxysilyl)propyl vinyl carbamate
  • N-(3-Aminopropyl)methacrylamide hydrochloride
  • (3-Acrylamidopropyl)trimethylammonium chloride
  • 2-Hydroxyethyl acrylate
  • N-Diphenylmethylacrylamide

Contact our Technical Project Management for support.

We are dedicated to customizing our services around your needs.
 

Silane Monomers*

Product No. Product Description
440159 3-(Trimethoxysilyl)propyl methacrylate
795402 3-[Tris(trimethylsiloxy)silyl]propyl vinyl carbamate
794368 3-(Trimethoxysilyl)propyl vinyl carbamate
446130 3-[Tris(trimethylsiloxy)silyl]propyl methacrylate
798266 Polydimethylsiloxane-diacrylamide
725676 Poly(ethylene glycol) diacrylamide
798118 Poly(dimethylsiloxane), monoacrylamidopropyl terminated
803936 Poly [silicone-alt-PEG] dimethacrylate

PEGs

Product No. Product Description
202401 Poly(ethylene glycol), Mn 600
295906 Poly(ethylene glycol), Mn 2,050
202444 Poly(ethylene glycol), Mn 3,350
181986 Poly(ethylene oxide), Mv 100,000
407348 Poly(ethylene glycol) phenyl ether acrylate, Mn 324
409537 Poly(ethylene glycol) methacrylate, Mn 360
447935 Poly(ethylene glycol) methyl ether methacrylate, Mn 300
447943 Poly(ethylene glycol) methyl ether methacrylate, Mn 500
329800 Tri(ethylene glycol) divinyl ether
172405 Tetraethylene glycol dimethyl ether
437441 Poly(ethylene glycol) diacrylate, Mn 575
335681 Ethylene glycol dimethacrylate
261548 Triethylene glycol dimethacrylate
437468 Poly(ethylene glycol) dimethacrylate, Mn 750
447943 Poly(ethylene glycol) methyl ether methacrylate, Mn 500

Crosslinkers

Product No. Product Description
246840 Trimethylolpropane trimethacrylate
412856 Diglycidyl 1,2-cyclohexanedicarboxylate
276685 Methacrylic anhydride
151238 Glycidyl methacrylate
114235 1,3,5-Triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione
216178 4,4'-Thiodiphenol
392111 Isobornyl methacrylate
477060 2-Isocyanatoethyl methacrylate
799181 Poly(dimethylsiloxane), bis-3-(silylpropyl vinylcarbamate)
803936 Poly [silicone-alt-PEG] dimethacrylate
795240 2-[2-(3-Prop-1-en-2-ylphenyl)propan-2-ylcarbamoyloxy]ethyl methacrylate

Initiators

Product No. Product Description
196118 2,2-Dimethoxy-2-phenylacetophenone
290785 Lauroyl peroxide
415952 Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide
437395 2-Ethylhexyl 4-(dimethylamino)benzoate
441090 2,2'-Azobis(2-methylpropionitrile)
458139 tert-Butyl hydroperoxide solution
M29959 4-Methylbenzophenone
124893 Camphorquinone
440914 2,2'-Azobis(2-methylpropionamidine) dihydrochloride
517909 Benzoyl peroxide
B8703 Benzoin methyl ether

 

Hydrophilic Monomers*

Product No. Product Description
109606 Methacrylamide
128635 2-Hydroxyethyl methacrylate
147230 Acrylic acid
155721 Methacrylic acid
415332 Ethylene glycol methyl ether methacrylate
64120 Methacryloyl chloride
276685 Methacrylic anhydride
63200 Maleic anhydride
560626 2-Isopropenyl-2-oxazoline
317624 Isophorone diisocyanate
V3409 1-Vinyl-2-pyrrolidinone
409472 N-[3-(Dimethylamino)propyl]methacrylamide
477028 2-Hydroxyethyl methacrylate
464244 Hydroxybutyl methacrylate, mixture of isomers
448281 (3-Acrylamidopropyl)trimethylammonium chloride solution
476234 2-Allyloxyethanol
731099 N-(3-Aminopropyl)methacrylamide hydrochloride
448281 (3-Acrylamidopropyl)trimethylammonium chloride
292818 2-Hydroxyethyl acrylate
245801 N-(Hydroxymethyl)acrylamide

UV Stabilizers

Product No. Product Description
413437 2-[3-(2H-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate

Dyes

CAS No. Product Description
13324-20-4 Reactive Blue 4
2580-78-1 Remazol Brilliant Blue R
17095-24-8 Remazol Black B
1328-53-6 Pigment Green 7
1309-37-1 Iron(III) oxide
147-14-8 Copper(II) phthalocyanine
13463-67-7 Titanium(IV) oxide

Contact lens manufacturing solvents

Product No. Product Description
792985 Specially Denatured Alcohol 200 proof, SDA 3A, contains Methanol
793000 Specially Denatured Alcohol 200 proof, SDA 3C, contains Isopropanol
563935 ISOPROPANOL, 70% in Water (Sigma-Aldrich)

* Custom Inhibitor Levels may be Possible upon Request.

Custom products are available on request.