Analytical

Ultra-High Performance using Fused-Core® HPLC Columns

This 28-minute Supelco HPLC web seminar discusses how to achieve ultra-high performance on any HPLC system using Ascentis® Express Fused-Core HPLC columns; also, how these columns help to reduce your solvent consumption.

 

Seminar Abstract

The web seminar covers the following points:

  • Introduction to the use of Fused-Core technology and Ascentis® Express columns with a variety of HPLC instruments, including traditional (6000-psi maximum) and ultra-high pressure (9-15,000 psi) systems.
  • Highlights of features such as higher sample throughput, lower solvent consumption, greater column ruggedness, more sensitivity and LC-MS compatibility; includes user data.
  • Applications of the Fused-Core RP-Amide phase and comparison to C18 and C8.
  • How to Improve LC-MS Speed and Sensitivity with rugged Fused-Core HPLC Columns
  • Emphasis on the use of short standard and small-bore columns with MS detection and high flow rates.
  • User applications data showing clear gains in speed and sensitivity at lower pressures than sub-2µm columns.

 

Presenter Profile

Richard Henry received his B.S. degree in Chemistry from Juniata College in 1963 and Ph.D. in Analytical Chemistry from The Pennsylvania State University in 1966. After a postdoctoral year in separations at Purdue University with Professor L. B. Rogers, he joined DuPont in 1967 at the Experimental Station in Wilmington, DE and became one of the first employees of the DuPont Instrument Products Division in 1969. Dick worked closely with Dr. Jack Kirkland and others in the development of HPLC columns and packing materials while at DuPont.

After about 10 years with Spectra-Physics and consulting on the west coast, he joined the Penn State University chemistry faculty in 1985 where he was Director of Analytical Laboratories and taught Instrumental Analysis to chemistry majors. In 1985, he also founded Keystone Scientific, Inc. where he developed HPLC columns and related separation technology. He retired from both Penn State University and Keystone Scientific in 2002, and remains active teaching short courses on separation technology and as a consultant.

Dick has research interests in separation mechanisms and all applications of new LC column technology. He is also interested in new analytical techniques, especially the rapidly growing fields of UHPLC, chiral HPLC, LC-MS, and multidimensional separation methods. He served two terms as Chairman of the ACS Subdivision on Separations (1998-2002) and has also served for many years on its Executive Committee.

 

Trademarks

Fused-Core - Advanced Materials Technology, Inc.