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Graphene-Based Nanomaterials for Versatile Biosensors

Overview

As a representative two-dimensional (2D) nanomaterial, graphene has attracted significant attention in the field of ultrasensitive sensors because of its excellent electronic and chemical properties, and large specific surface area. In an electronic biosensor, graphene-based materials are functionalized with gold nanoparticle (NP)-antibody conjugates and used as a conducting channel in a field-effect transistor (FET). Electrical detection of protein binding is accomplished through FET and direct current (dc) measurements. In an electrochemical biosensor, highly electrocatalytic metal oxides are combined with graphene-based materials to offer both a high electrocatalytic activity and a high electrical conductivity for enzymeless biosensing. Biomolecules are then detected through electrochemical measurements such as cyclic voltammetry. The aforementioned graphene-based platforms can be used for the detection of Escherichia coli (E. coli) bacteria, glucose, and various proteins.

Areas Covered in the Webinar

  • Introduction to graphene-based nanomaterials
  • Protein detection using reduced graphene oxide (rGO) and vertical graphene (VG)
  • Real-time detection of E.coli bacteria in water using rGO
  • Enzymeless glucose sensing using crumpled graphene (CG)
  • Electronic sensing and electrochemical sensing

Who Should Watch?

  • Material Scientists
  • Nanomaterials Engineers
  • Chemical Engineers
  • Anyone interested in graphene or 2D materials


Dr. Junhong Chen is a Distinguished Professor of Mechanical Engineering and Materials Science and engineering and an Excellence in Engineering Faculty Fellow in Nanotechnology at the University of Wisconsin-Milwaukee (UWM).  He is also the Director of NSF I/UCRC on Water Equipment & Policy and the founder of NanoAffix Science LLC.  Dr. Chen received his B.E. in Thermal Engineering in 1995 from Tongji University, and his M.S. and Ph.D. in Mechanical Engineering in 2000 and 2002, respectively, from the University of Minnesota.  Prior to joining UWM in 2003, he was a postdoctoral scholar in Chemical Engineering at the California Institute of Technology. His current research focuses on nanocarbon-based hybrid nanomaterials for sustainable energy and environment.  Dr. Chen has 6 patents, 6 pending patents, and 9 licensing agreements. He has also published 200 journal papers on various nanomaterials, sensors, and energy devices that have received over 7,000 citations with an h-index of 48.  He is the recipient of several awards including the 2008 UWM Foundation Research Award, 2012 UWM College of Engineering & Applied Science Research Excellence Award, 2014 UWM Research Foundation Senior Faculty Research Award, 2015 Inaugural Regent’s Scholar of the UW System, and 2016 International Association of Advanced Materials (IAAM) Medal. He is also an elected Fellow of the American Society of Mechanical Engineers (ASME), and the National Academy of Inventors. His start-up company NanoAffix won the 2016 Wisconsin Innovation Award.