Business Development

Out-Licensing Opportunities

RNAi Opportunities

Lentiviral delivery technology
Patent (364 Kb PDF)
Sigma-Aldrich Corporation is the exclusive worldwide licensee of U.S. Pat. Nos. 5,817,491; 5,591,624; 5,716,832; 6,312,682; 6,669,936; 6,235,522; 6,924,123 and foreign equivalents from Oxford Biomedica Ltd., Oxford, UK.

DNA-directed RNA interference
Patent (56 Kb PDF)
Sigma-Aldrich Corporation is also the exclusive worldwide licensee for certain fields of U.S. Pat. No. 6,573,099 and foreign counterparts co-owned by Benitec Australia, Ltd. and the Australian Commonwealth Scientific and Industrial Research Organization (CSIRO) both of Australia.

Sigma-Aldrich is making available sublicenses of the licensed patents as well as making available licensed Lentivirus-based shRNA Libraries for purchase through its catalog and web sites.

  • For a commercial license to the DNA-directed RNA interference IP, please visit the Benitec Web site.
  • For information on research licenses, please contact: businessdevelopment@sial.com

 


FLAG® Opportunities

Multiple Epitopes for Identification and Purification of Recombinant Proteins and
FLAG / ANTI-FLAG Trademarks
Cleavable Multiple-FLAG (DYKDDDDK) epitope-tag expression and purification technology.
Use of FLAG / Anti-FLAG trademarks.
Discovery Tools • Primary Screening
• Secondary Screening (e.g. cell biological profiling or high content screening)
• Target Discovery (proteomic or genomic based)
• Target Validation (proteomic or genomic based)
• Protein Expression
Marketing Rights
Available/Desired
• Worldwide
Publications • Patents: US 6,379,903 (459 Kb PDF); US 7,094,548 (225 Kb PDF)

 


HIS-Select® Opportunities

HIS-Select Metal Chelate Composition Technologies
HIS-Select technology is a proprietary metal chelate with superior specificity over conventional nitrilotriacetic acid resins. HIS-Select technology is also trademark registered.
Discovery Tools • Protein Expression
Marketing Rights
Available/Desired
• Worldwide
Publications • Patents: US 7,033,520 (799 Kb PDF); US 6,623,655 (998 Kb PDF);
  US 7,709,612 (90 Kb PDF)

 


REDTaq® & REDAccuTaq® Opportunities

REDTaq and REDAccuTaq are based on an invention using tracer reagents to enhance PCR and RT-PCR reaction-product analysis enabling simple direct gel loading for visualization.
Discovery Tools • Genomics
Marketing Rights
Available/Desired
• Worldwide
Publications • Relevant patent and patent applications: US 6,942,964 (1.3 Mb PDF); 
  US 7,169,584 (282 Kb PDF); US20080160518 (330 Kb PDF).
  REDTaq and REDAccuTaq are registered trademarks of Sigma-Aldrich Co. LLC

 


Whole Genome Amplification Opportunities

Whole Genome Amplification Technology
Discovery Tools • Pharmacogenetics/genomics
Marketing Rights
Available/Desired
• Worldwide
Field of use restriction • Research use and service providers
Publications US Patent No. 7,718,403 (1.33 Mb PDF)
  International Application No. PCT/US204/00693 Titled "Amplification and
  Analysis of Whole Genome and Whole Transcriptome Libraries Generated
  by a DNA Polymerization Process"

 


Whole Transcriptome Amplification Opportunities

Whole Transcriptome Amplification Technology
Discovery Tools • Pharmacogenetics/genomics
Marketing Rights
Available/Desired
• Worldwide
Field of use restriction • Research use and service providers
Publications US Patent No. 7,718,403 (1.33 Mb PDF) 
  International Application No. PCT/US204/00693 Titled "Amplification and
  Analysis of Whole Genome and Whole Transcriptome Libraries Generated
  by a DNA Polymerization Process"

 


Chemistry Opportunities

Borane-Sulfide Hydroboration Agents
US Patent 5,567,849 (465 Kb PDF)

Dioxane-Monochloroborane and Dioxane-Dichloroborane
US Patent 6,008,414 (386 Kb PDF)

Stabilized Borane-Tetrahydrofuran Complex
US Patent 7,767,833 (951 Kb PDF)

 

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