RNAi Opportunities
Lentiviral delivery technology
Patent (364 Kb PDF)
Sigma-Aldrich Corporation is the exclusive worldwide licensee of U.S. Pat. Nos. 5,817,491; 5,591,624; 5,716,832; 6,312,682; 6,669,936; 6,235,522; 6,924,123 and foreign equivalents from Oxford Biomedica Ltd., Oxford, UK.
DNA-directed RNA interference
Patent (56 Kb PDF)
Sigma-Aldrich Corporation is also the exclusive worldwide licensee for certain fields of U.S. Pat. No. 6,573,099 and foreign counterparts co-owned by Benitec Australia, Ltd. and the Australian Commonwealth Scientific and Industrial Research Organization (CSIRO) both of Australia.
Sigma-Aldrich is making available sublicenses of the licensed patents as well as making available licensed Lentivirus-based shRNA Libraries for purchase through its catalog and web sites.
FLAG® Opportunities
| Multiple Epitopes for Identification and Purification of Recombinant Proteins and FLAG / ANTI-FLAG Trademarks |
|
| Cleavable Multiple-FLAG (DYKDDDDK) epitope-tag expression and purification technology. Use of FLAG / Anti-FLAG trademarks. |
|
| Discovery Tools | • Primary Screening • Secondary Screening (e.g. cell biological profiling or high content screening) • Target Discovery (proteomic or genomic based) • Target Validation (proteomic or genomic based) • Protein Expression |
| Marketing Rights Available/Desired |
• Worldwide |
| Publications | • Patents: US 6,379,903 (459 Kb PDF); US 7,094,548 (225 Kb PDF) |
HIS-Select® Opportunities
| HIS-Select Metal Chelate Composition Technologies | |
| HIS-Select technology is a proprietary metal chelate with superior specificity over conventional nitrilotriacetic acid resins. HIS-Select technology is also trademark registered. | |
| Discovery Tools | • Protein Expression |
| Marketing Rights Available/Desired |
• Worldwide |
| Publications | • Patents: US 7,033,520 (799 Kb PDF); US 6,623,655 (998 Kb PDF); US 7,709,612 (90 Kb PDF) |
REDTaq® & REDAccuTaq® Opportunities
| REDTaq and REDAccuTaq are based on an invention using tracer reagents to enhance PCR and RT-PCR reaction-product analysis enabling simple direct gel loading for visualization. | |
| Discovery Tools | • Genomics |
| Marketing Rights Available/Desired |
• Worldwide |
| Publications | • Relevant patent and patent applications: US 6,942,964 (1.3 Mb PDF); US 7,169,584 (282 Kb PDF); US20080160518 (330 Kb PDF). REDTaq and REDAccuTaq are registered trademarks of Sigma-Aldrich Co. LLC |
Whole Genome Amplification Opportunities
| Whole Genome Amplification Technology | |
| Discovery Tools | • Pharmacogenetics/genomics |
| Marketing Rights Available/Desired |
• Worldwide |
| Field of use restriction | • Research use and service providers |
| Publications | • US Patent No. 7,718,403 (1.33 Mb PDF) International Application No. PCT/US204/00693 Titled "Amplification and Analysis of Whole Genome and Whole Transcriptome Libraries Generated by a DNA Polymerization Process" |
Whole Transcriptome Amplification Opportunities
| Whole Transcriptome Amplification Technology | |
| Discovery Tools | • Pharmacogenetics/genomics |
| Marketing Rights Available/Desired |
• Worldwide |
| Field of use restriction | • Research use and service providers |
| Publications | • US Patent No. 7,718,403 (1.33 Mb PDF) International Application No. PCT/US204/00693 Titled "Amplification and Analysis of Whole Genome and Whole Transcriptome Libraries Generated by a DNA Polymerization Process" |
Chemistry Opportunities
Borane-Sulfide Hydroboration Agents
US Patent 5,567,849 (465 Kb PDF)
Dioxane-Monochloroborane and Dioxane-Dichloroborane
US Patent 6,008,414 (386 Kb PDF)
Stabilized Borane-Tetrahydrofuran Complex
US Patent 7,767,833 (951 Kb PDF)
back to top
Back to Business Development