Custom Oligo Synthesis

As the world's leading supplier of oligonucleotides to the life science community, Sigma-Aldrich® delivers the largest portfolio of capabilities and expertise for our Commercial and OEM partners.

Partner with Sigma-Aldrich and experience unsurpassed versatility in oligo manufacturing and process development, outstanding customer service and support, global production and distribution capabilities and a commitment to quality that you can trust through:

A Comprehensive Oligo Portfolio

  • DNA oligos with a breadth of synthesis scales, purification and modifications
  • Custom formats for high-throughput applications, including:
    • 96 or 384 well plates (tube and plate options available)
    • Concentration ranges: 20-200 µM with fixed or variable volumes
    • Supplied lyophilized or in solution with customized buffers
    • Daughter plates
    • Forward and Reverse Primers in a single well
  • Dual-Labeled Fluorogenic Probes
  • iScale Oligos™ (milligram to gram quantities of DNA) for in vitro and in vivo projects

Quality and Consistency

  • Robust Quality Management Systems
  • ISO 9000, ISO13485 and GMP
  • State-of-the-art analytical instrumentation and laboratories
  • Stringent in-process controls
  • Customer defined Certificates of Analysis (CoA)

Expertise

  • Proactive customer service and dedicated project management
  • Challenging chemistry and novel synthesis methods
  • Detailed process development
  • Manufacturing

Secure Supply Chain

  • Unsurpassed product breadth
  • Vendor consolidation
  • Supply chain management
  • Global manufacturing and distribution
  • Supply agreements