Protein Of The Month

 

April: Citrate Synthase
Origin: Cellular respiration is an important conduit for molecular energy transfer. Citrate Synthase is an important enzyme in this process. This enzyme is found in nearly all cells capable of oxidative metabolism.
Application: Citrate synthase is often used as a quantitative enzyme marker for the presence of intact mitochondria.
How: Citrate synthase catalyses the conversion of citrate to acetyl-CoA in the presence of coenzyme-A with the release of H2O and oxaloacetate.
Did you know: Citrate Synthase plays a key role at the start of the citric acid cycle (a.k.a Krebs cycle). The Krebs cycle uses O2 to generate CO2 and chemical energy from molecular fuels.
 

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