Protein Of The Month

January: Trypsin
Origin: Trypsin is a serine protease found in the digestive system of many vertebrates, where it hydrolyses proteins. Human Trypsin is produced in the pancreas.
Application: The typical laboratory use for Trypsin is in removing adherent cells from a culture surface. Trypsin is also used to re-suspend cells during cell culture, and in proteomics research for controlled digestion of proteins. Additional applications include assessment of crystallization by membrane-based techniques, and determination of protein folding.
How: Trypsin cleaves peptides on the C-terminal side of lysine and arginine residues.
Did you know: Trypsin is also used in commercial food processing as a baking enzyme to improve workability of dough.
 

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