Sigma® Life Science Extends Research Model Portfolio Into Oncology and Carcinogenicity Screening; Introduces World's First p53 Knockout Rat ST. LOUIS, April 19, 2010 /PRNewswire via COMTEX News Network/ -- Sigma® Life Science, the innovative biological products and services brand of Sigma-Aldrich® (Nasdaq: SIAL), today introduced the world's first p53 'knockout' rat model, an important development that is expected to, due to the rat's closer physiological and metabolic similarity to humans, significantly improve timelines for carcinogenicity screening and reduce time to market for therapeutics. Read More...