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St. Louis, MO - October 29, 2014 SAFC Launches New Protein Quality Supplement to Increase N-linked Glycosylation

Sigma-Aldrich® Corp. (NASDAQ: SIAL) today announced that SAFC® Commercial (www.safcglobal.com), its custom manufacturing services business unit, has introduced a new protein quality supplement called EX-CELL® Glycosylation Adjust (Gal+).

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St. Louis, MO - October 16, 2014 BioReliance® Introduces Advanced In Vitro ADME and Toxicology Services Designed to Improve Drug Safety and Efficacy

BioReliance, Sigma-Aldrich Corporation’s (NASDAQ: SIAL) biologics and early-development services business under SAFC® Commercial, has introduced select in vitro ADME (absorption, distribution, metabolism and excretion) and toxicology testing services for pharmaceutical, chemical and industrial consumer products to its service offering.

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St. Louis, MO - October 3, 2014 Sigma-Aldrich Agrees To Acquire Cell Marque To Strengthen Immunohistochemistry Business

Sigma-Aldrich Corporation (NASDAQ: SIAL) announced today that it has entered into an agreement to acquire Rocklin, California, based Cell Marque Corporation in a move to strengthen its antibody portfolio and to better serve immunohistochemistry (IHC) customers.

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St. Louis, MO - September 24, 2014 SAFC and Baxter BioPharma Solutions Collaborate on Complete ADC Offering

Sigma-Aldrich Corporation’s SAFC® Commercial custom manufacturing services business unit, and Baxter’s BioPharma Solutions business have established a collaborative manufacturing agreement. SAFC will contribute extensive expertise in conjugation and the manufacture of drug linkers, while BioPharma Solutions will offer world-class, sterile fill/finish services for final filling of ADC products.

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