This thoroughly revised and updated Third edition offers eight new chapters covering topics such as microchip and biosensor technologies, the validation of chromatographic methods, gel permeation and size exclusion chromatography, field-flow fractionation, countercurrent chromatography, hyphenated techniques in chromatography, and thin-layer chromatography. The text studies a vast array of modern technologies and instrumentation practices-providing a firm foundation in theory and methodology, as well as current applications in the field It presents examples of commercially available equipment that illustrate design features discussed in the text and provides a guide for workers in analytical chemistry who need a starting place for information about a specific instrumental technique
Provides fast, hands-on access to thousands of abstracts from the current literature on HPLC methods for pharmaceutical analysis. The most commonly used method for analyzing substances, and the first method most researchers turn to, is high performance liquid chromatography (HPLC). Following up on a best-seller, volumes 1-4 continue to provide an easily-accessible collection of procedures for analyzing pharmaceuticals using HPLC.
This handbook compiles the most comprehensive information on over 200 water-based and solvent-based indicators. Organized alphabetically, entries include: common name, other names, CA index name, CAS registry number, Merck index number, chemical structure, chemical/dye class, molecular formula, molecular weight, pH range, color change at pH, pKa, physical form, solubility, UV-visible, melting point, and boiling point. This resource also offers unique coverage including protocols for synthesizing indicator compounds; data relating to adverse effects, toxicity, and major applications for each indicator. The handbook contains practical information for applications that include semiconductors, fuel cells, sensors, surface coatings, adhesives, agricultural chemicals, textiles, personal care products, pharmaceuticals, and detection of disease.
This 400 page book contains comprehensive description of the fundamental principles of solid phase microextraction, recent applications, SPME devices and procedures published to date. SPME protocols are presented in a step-by-step fashion, providing useful tips and potential pitfalls. The important steps in SPME method development and optimization including calibration are clearly discussed to assist new users of the technology. This handbook enables researchers at all stages of their careers to effectively apply this convenient and solvent free sample preparation to solve their analytical challenges in effective way. This up-to date handbook contains 13 chapters.
Topics covered include: Theory of SPME, SPME devices and fibre coatings, commercial devices and coatings, automated SPME systems, calibration of extraction step, SPME method development, ligand-receptor binding, in-vivo SPME, review of different application areas including: environmental, food and fragrance, forensic and drug analysis as well as SPME protocols. In addition the book contains a CD with SPME presentations and description of beginning experiments helpful in designing course and lectures on the topic.
Solid materials leave distinct patterns similar to fingerprints if they are x-rayed. x-ray powder diffractometry is an established technique used to fingerprint and identify samples such as moon rocks or pharmaceutical ingredients. This book provides an up-to-date, thorough introduction to the field, with clear, concise descriptions of both theory and practice.
English translation and revised edition of the German monograph (Fluka No. 58165) describing theory, preparation and application of ion-selective optode membranes as well as recent developments in this field.With 237 references. Visit our Sensor Applications portal to learn more.