 | A0347 | Advanced Methods In Cellular Immunology | Immunologists often use protocols involving isolation, culture and characterization of different types of leukocytes. In this collection of techniques, each chapter contains a step-by-step description of the methodology, alternative techniques, pertinent references, and information about commercial sources for materials and reagents. It also includes processes of cell culture as well as inflammation and autoimmunity in animal models. Covering PCR and apoptosis, this book is a guide to common procedures in cellular immunology while utilizing both human and murine models.
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| | Z374164 | Advances in Immunology: Volume 63 | The next volume in a series which all immunologists need. This edition features sections on the role of CD40 and its ligand gp39, as central players, in the regulation of Bcell growth and differentiation. A section on prolactin, growth hormone and insulin-like growth factor-I as full-fledged immunological growth and differentiation factors can also be found, as well as many other sections on new and stimulating ideas for immunology.
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 | Z702579 | Antibodies Volume 1: Production and Purification | This book presents an overview of the current advances applied in the manufacture of monoclonal antibodies including concepts in development of manufacturing strategies; importance of antibody fragments; application of chromatography method development; quality control; effect of expression on antibody properties; virus removal and safety; pharmacokinetics; regulatory aspects. Together with Volume 2 (Z70,258-7), these books present a comprehensive account of the current state-of-the-art in the manufacture and application of monoclonal antibodies, and provide an insight into future possibilities.
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 | A2926 | Antibodies: A Laboratory Manual | This book places the production and use of polyclonal and monoclonal antibodies within the reach of every biologist. All of the techniques described are supplemented with extensive notes and two-color illustrations.
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| | Z368709 | Antibody Engineering Protocols | This collection of recently developed methods for producing new antibody reagents by immunization and recombinant DNA techniques contains ready-to-use protocols that illuminate current areas of research on antibody structure, functions and applications. They offer insight into new ways of developing clinically useful antibody reagents.
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 | Z701858 | Antibody Engineering: Methods and Protocols | A collection of techniques for the generation, expression, optimization, and characterization of recombinant antibodies. Reproducible protocols for lead generation range from the cloning of human immunoglobulin genes to the selection and generation of human recombinant antibodies by humanization approaches, molecular display technologies and transgenic animals. Included are procedures on restructuring antibody leads into monovalent, multivalent, and bispecific binding fragments for a variety of in vivo applications. Technologies are described for the characterization of antigen-binding affinity and specificity.
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 | A7349 | Antibody Phage Display | This book covers the protocols highlighting the latest gains in antibody phage display which have made it the definitive technology for monoclonal antibody production. The contributors provide protocols with simplicity and clarity that cover the broad scope of the technology including the key areas of library construction, screening, antibody modification, and expression. The protocols will allow for new opportunities in immunotherapy, drug discovery, and functional genomics.
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 | Z705837 | Antigen Presenting Cells: From Mechanisms to Drug Development | This novel, multidisciplinary handbook highlights recent evidence that antigen presenting cells (APCs) are not only key players in the initiation or prevention of an antigen-specific T lymphocyte-mediated adaptive immune response, but also critical regulators and integrators in the interplay between our innate and adaptive immune system. Structured in a clear way to allow access to a very broad readership, the book is written from the viewpoint of a biochemist, immunologist, and scientist with experience in drug development. It covers all cell types involved in antigen presentation, providing the latest immunological facts with a focus on drug development. This short but comprehensive reference covers basic introductory aspects right up to details for advanced specialists.
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 | A6346 | Antigen Processing and Presentation Protocols | Drawing on expertise, investigators describe step-by-step methods designed to question how major histocompatibility complex-binding peptides are generated, to test how peptides are delivered to MHC molecules, to analyze MHC peptide-binding patterns, and to assay the T-cell response to the MHC/peptide complex. Emphasis is given those technical steps critical for experimental success that are often omitted from methods published in the primary literature.
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 | Z700711 | Apoptosis and Autoimmunity: From Mechanisms to Treatments | This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.
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| | Z703834 | Atlas of Immunology, 2nd ed. | With more than 1100 computer-generated figures, line drawings, and photographs, this book clearly demonstrates that "a picture is worth a thousand words." Written for students, basic scientists, and clinicians, this second edition provides a thorough and up-to-date treatment of all the concepts needed to comprehend contemporary immunology. The coverage ranges from photographs of historical figures to molecular structures of recently characterized cytokines, major histocompatibility complex molecules, immunoglobulins, and molecules of related interest. It presents new topics in immunology, molecular structures, and mechanics of molecular and cellular interactions and serves as a valuable aid for surgical pathology through diagnostic immunohistochemistry while including all autoantibodies of significance in diagnostic immunopathology
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 | B4931 | Basic Methods in Antibody Production and Characterization | This manual uses a cookbook approach to presenting the methods for the production, characterization, and use of antibodies. Antibodies described include polyclonal and monoclonal and those made by the phage display. It focuses on specific aspects of antibodies and takes readers on a step-by-step process from antigen preparation to immunizations, adjuvants, screening, purification, storage, and applications. Ample references provide researchers with many applications pertaining to the technology.
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 | Z703389 | Catalytic Antibodies | Exploiting the inherent combinatorial mechanism in the biosynthesis of antibodies, an almost limitless variety of biocatalysts may be generated. Catalytic antibodies are capable of performing almost any type of reaction with high selectivity and stereospecificity. Here, the pioneers in the use of catalytic antibodies review the entire scope of this interdisciplinary field, covering such topics as: theoretical aspects of structure, mechanism and kinetics; practical considerations, from immunization techniques to screening methods; in vitro evolution and other modern approaches; applications from organic synthesis to medical uses. This is the first book to provide such comprehensive coverage and will be the prime reference for biochemists, organic chemists, biotechnologists and biomedical researchers.
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| | Z357456 | Cellular Immunology: Labfax | This volume condenses the large body of information available on cells of the immune system. It provides access to details of immune system tissues, cells and molecules − their development, structure, function, preparation and assay.
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 | Z730998 | Cellular and Molecular Immunology 6th ed. | An exceptionally lucid guide to the latest immunology concepts! Through five best-selling editions, readers worldwide have appreciated this book′s in-depth yet straightforward, richly illustrated approach to this complex subject. Now, sweeping updates incorporate the latest discoveries about innate immunity, the organization of lymphoid organs, and many other cutting-edge topics. Plus, online access via STUDENT CONSULT makes this an even more powerful learning resource!
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| | Z369365 | Clinical Immunology: An Illustrated Outline | A succinct review of clinical immunology covering the mechanisms behind disease. It includes examples of diagnostic tests so the reader can find the underlying immunological proceses. The book is organized by key term headings followed by a concise definition. It serves as an illustrated dictionary as well as a review tool.
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 | C1979 | Complement Methods and Protocols | A set of readily reproducible methods and cutting-edge techniques is directed to those interested in understanding complement’s mechanisms of activation and to those wishing to quantify its activation, and range from the purification of its components to generating complement-deficient mice by gene deletion. Additional techniques include procedures for the analysis of its function, for the study of its regulators, for detection of its activation in vivo, and for the identification of its autoantibodies.
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 | Z700436 | Cytokine Factsbook and Webfacts, 2nd ed. | This second edition is the most up-to-date reference manual available for all well-characterized interleukins, cytokines, and their receptors. An additional 52 cytokines are included, doubling the number of entries from the previous edition. The key properties of each cytokine are described and presented in a very accessible format with diagrams for each of the receptors. It includes free online access to Cytokine Webfacts. Cytokine Webfacts is a web-based compendium of facts about cytokines and their receptors that includes a variety of data representations, such as text, signal pathway diagrams and 3D images.
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 | Z701629 | Cytokine Handbook, 4th ed. 2 volume set | The fourth edition provides encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes with contributions from more than 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for anyone interested in cytokines and working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics.
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 | C2606 | Cytokine Molecular Biology: A Practical Approach | This manual concentrates on molecular biology techniques for the study of cytokines, cytokine receptors, and cytokine driven processes. Topics include the cloning and expressing of cytokine genes, the analysis of cytokine mRNA by RT-PCR, cDNA array systems and in situ hybridization, the study of cytokine gene polymorphisms, the analysis of cytokine signaling via PC-specific phospholipase C and sphingomyelinases, the Jak/STAT and MAPK signaling pathways, and gene modification in transgenic and mutant mice.
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 | C2479 | Cytokine Network | Cytokines act in a complex network where one cytokine can influence production of, and response to other cytokines. This book covers the study of cytokine and cytokine receptor structure, elucidation of convergent intracellular signaling pathways, molecular genetics, and targeted gene disruption to ′knock-out′ production of individual cytokines in mice. It is not a survey of individual cytokines, but a guide to the cytokine network covering genomics, signaling pathways, control of the immune response, and therapeutics.
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 | Z730637 | Diagnostic Immunohistochemistry 2nd ed. | The New Edition of this popular text features world-renowned experts who offer the most current information and reliable guidance on immunohistochemical diagnoses in surgical pathology and cytopathology. The book is organized in a consistent format of organ systems, specifically designed to target diagnostic dilemmas in surgical pathology. Each chapter features an introduction and a systematic approach to the diagnostic entities of that organ system. Readers will also find easy-to-understand diagnostic algorithms and "immunohistograms" that depict immunostaining patterns of tumors, as well as charts, tables, and high-quality color histologic images that assist in making a definitive diagnosis
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 | E2027 | ELISA Guidebook | This is today′s premier practical guide to the understanding and application of ELISA. Updating Crowther′s publication, ELISA Theory and Practice (1995), this book introduces chapters on such major new topics as checkerboard titrations, quality control of testing, kit production and control, novel monoclonal antibodies, validation of assays, statistical requirements for data examination, and epidemiological considerations. It contains numerous worked examples, detailed instructions, and extensive illustrations.
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 | Z370258 | Enzyme Immunoassays: From Concept to Product Development | A vertical exposition of enzyme immunoassays; the intended audience is product designers and R&Dgroups who aim to commercialize EIA technology. From concepts of antibody and antigen through laboratory development, all the way to manufacturing, marketing, and regulatory compliance, the book is a practical resource for the diagnostic field.
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 | Z373990 | Epitope Mapping Protocols: Methods in Molecular Biology, Vol. 66 | This manual offers more than thirty protocols for antibody production and mapping. Methods range from those that use (or can use) whole, native antigens to those that require antigen expressed from recombinant DNA. Methods for T-cell epitopes and techniques for producing panels of antibodies for epitope mapping are also included.
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 | E4527 | Epitope Mapping: A Practical Approach | This book covers major methods for identification and definition of epitopes. Pepscan assay is used to define B cell epitopes and makes use of synthetic peptides. Site directed mutagenesis is a powerful tool and can be used to evaluate the role of single amino acids in immune complex formation. Protein footprinting relies on the fact that the epitope is protected from cleavage when bound as an antibody-antigen complex. Random phage display libraries can be screened with antibody and resulting DNA sequenced to confirm the amino acid sequence of a specific epitope.
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 | Z702862 | Flow Cytometry Protocols 2nd ed. | These reproducible methods deploy emerging flow cytometry technologies in many applications. Here, the aspiring investigator will find methods for the characterization of stem/progenitor cells by monitoring the efflux of fluorescent dyes and the elucidation of signal transduction pathways using phospho-specific antibodies. There are also techniques for monitoring gene transfer and expression using fluorescent protein technology, high throughput screening for discovery of novel protein interactions, phenotypic and functional characterization of T cell subsets and precursors, and microbial flow cytometry.
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 | F1049 | Flow Cytometry: A Practical Approach, 3rd ed. | This is a handbook for every laboratory that has a bench-top flow cytometer or a fluorescence activated cell sorter. It is a guide for those new to the field and a first point of reference for experienced practitioners who want to investigate a new technique. Flow cytometry has found increasing application in the field of apoptosis research, and a new chapter has been added to cover this important topic.
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 | F0178 | Flow Cytometry: First Principles, 2nd ed. | With advances in flow cytometry, this edition provides an update, reflecting innovations while outlining the fundamental elements of instrumentation, sample preparation, and data analysis. It explains the basic principles of flow cytometry, surveys scientific and clinical applications and highlights state-of-the-art techniques. This edition contains revisions of all chapters with new discussions on fluorochrome and laser options for multicolor analysis, an additional section on apoptosis in the chapter on DNA, and new chapters on intracellular protein staining and cell sorting, including high-speed sorting and alternative sorting methods, as well as traditional technology.
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 | G2793 | Gold and Silver Staining: Techniques in Molecular Morphology | Immunogold silver staining is one of the most sensitive techniques for visualizing the location of antibodies and nucleotide probes. Contributors cover the latest developments and a range of applications from highly sensitive detection of antigens to single copy detection of DNA and RNA. This book presents descriptions that allow visualization of molecules never localized before. It also provides a selection of protocols with high sensitivity; presents techniques for cytochemistry, histochemistry, in situ hybridization, and immunoblotting applications; discusses the applications to cancer research; offers suggestions, tips, and guidelines to avoid unspecific precipitations; analyzes advantages and drawbacks of staining methods.
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 | Z704164 | Handbook of ELISPOT: Methods and Protocols | In this book on ELISPOT, a critical enzyme-linked immunospot assay, experts detail how to design, perform, and analyze these assays. The techniques cover a wide variety of topics, including the use of membrane-backed plates, the standardization and validation procedures, the removal of cells from ELISPOT plates, cell separation techniques, and the quantification of ELISPOT data. There are also numerous ELISPOT applications involving animal models, human cells, measles, multiple sclerosis, immune responses, multicytokine detection systems, and immunocytochemistry. Highlights include dual-color and multiplex ELISPOT assays, use of the ELISPOT assay on feline lymphocytes, standardization of the ELISPOT procedure, and combining the ELISPOT assay with immunohistochemistry.
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 | Z375632 | Handbook of Human Immunology | This book provides a complete guide to molecular immunology. The basic principles underlying assays of the immune system are discussed as are the application and interpretation of immune tests. It emphasizes the molecular basis for induction and regulation of immune responses; discusses cell receptors and accessory molecules, cytokines, growth factors and interleukins and their application in the diagnosis of various diseases; reviews serological testing for infectious diseases and the application of molecular biological techniques; and 115 tables summarize textual information.
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| | Z359327 | Hybridomas and Monoclonal Antibodies VHS PAL | This video guide, produced at the University of Pittsburgh Hybridoma Center, demonstrates the technical steps required for the successful production of antibodies: immunization and bleeding of mice, fusion of spleen cells and myeloma cells with PEG and DMSO, HAT selection and screening off positive cultures and growth of hybridoma lines. The demonstrations are accompanied by audio commentary on the procedures involved and their theoretical basis. (32 minutes)
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 | Z704059 | Illustrated Dictionary of Immunology, 2nd ed. | Immunologists have always maintained a unique nomenclature that has mystified and even baffled their colleagues in other fields, causing them to liken immunology to a "black box." With more than 1,200 illustrations that depict every concept of importance, this second edition provides immunologists and nonimmunologists alike a single-volume resource for the many terms encountered in contemporary immunological literature. Encyclopedic in scope, the content ranges from photographs of historical figures to molecular structures of recently characterized cytokines, the major histocompatibility complex molecules, immunoglobulins, and molecules of related interest to immunologists. Since the first edition, there has been an exponential increase in immunological information and this text represents these advances.
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 | Z705713 | Immune Response: Basic and Clinical Principles | The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. Includes a CD-ROM containing all the figures and plates appearing in the book.
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| | Z373672 | Immunoassay | An indispensable guide to information on the theory and practice of immunoassays. This book balances the content among theory, practical issues, quality control, automation, and subspecialty areas. Protocols for specific assays are included.
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 | Z704040 | Immunoassay Handbook, 3rd ed. | This third edition offers a balanced review of practical information and clinical applications in the field of immunoassay technology. Comprehensive and expertly written, this handbook will be invaluable for a wide range of users from researchers developing immunoassay systems to developmental and marketing staff who need an excellent overview of how immunoassay principles, systems and applications work. With 68 chapters covering a wide range of topics, and new chapters looking at: surface plasmon resonance in kinetic, concentration and binding site analyses, and the foundations of immunochemistry, this handbook is a must read for all laboratory researchers and academics who use immunoassay as a tool.
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 | I7893 | Immunoassays: A Practical Approach | This is designed to help biologists develop an immunoassay of any common format for any suitable analyte. The basic principles are described and the choices of assay types and formats listed. Methods for raising and for characterizing antibodies, for preparing radioactive, enzymatic, fluorescent and other labels, are described. Solid-phase reagents, standards and immunogens are explained, with procedures for their preparation. Most components can now be obtained commercially.
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 | Z702765 | Immunobiology:The Immune System in Health and Disease, 6th ed. | This text guides the reader through the immune system from the first engagement of innate immunity to the generation of the adaptive immune response and its clinical consequences. The order of topics has been altered to place related material together. Each chapter has been updated to incorporate new observations that extend our knowledge and understanding of the immune system. Immunobiology 6 Interactive, a CD-ROM packaged with the book, contains every figure in the text, and animations and videos with voiceover narration.
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 | Z703281 | Immunochemical Protocols, 3rd ed. | This new edition of a much praised classic includes both basic method for producing and using antibodies and advanced techniques required by today′s state-of-the art investigators. The basic sections of the book stress the first principles of antibody production and guide the reader through the processes and pitfalls of immunochemistry. The advanced sections focus on specific applications and cover the immunochemical techniques now used in laboratories. New material includes techniques for making new monoclonal cell lines, for producing good quality monoclonal antibodies, immunocapture PCR, immunoaffinity purification, and immunoelectron microscopy in plant virus diagnosis.
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 | I5653 | Immunocytochemical Methods and Protocols, 2nd Edition | This 2nd edition revises and updates the previous collection of step-by-step immunocytochemical methods now used in many biological and biomedical research programs. The methods are designed for researchers and clinicians that wish to visualize molecules in plant or animal embryos, tissue sections, cells, or organelles. In addition to cutting-edge protocols for purifying and preparing antibodies, light microscopic analysis, confocal microscopy, FACS, and electron microscopy are also covered.
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 | Z340804 | Immunodiagnostics: A Practical Approach | | pricing |
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 | Z719188 | Immunohistochemistry: Methods Express Series | Immunohistochemistry remains a cornerstone technique in biomedical research, with an ever expanding range of applications. Immunohistochemistry: Methods Express is structured to reflect the modern applications of immunohistochemistry, combining emphasis on the growing trend towards automation and high throughput technology, with clear descriptions of the traditional methodology.
The book covers the key techniques, such as: Immunolabeling - specimen preparation, fixation, antigen retrieval, and staining methods; Choice of antibodies and selection of reporter probes; Confocal microscopy and immunohistochemistry; Multiple immunolabeling; Image capture, analysis and quantification; Automation; Quality assurance and troubleshooting
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 | Z719161 | Immunohistochemistry: Methods Express Series Hardcover | Immunohistochemistry remains a cornerstone technique in biomedical research, with an ever expanding range of applications. Immunohistochemistry: Methods Express is structured to reflect the modern applications of immunohistochemistry, combining emphasis on the growing trend towards automation and high throughput technology, with clear descriptions of the traditional methodology.
The book covers the key techniques, such as: Immunolabeling - specimen preparation, fixation, antigen retrieval, and staining methods; Choice of antibodies and selection of reporter probes; Confocal microscopy and immunohistochemistry; Multiple immunolabeling; Image capture, analysis and quantification; Automation; Quality assurance and troubleshooting
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| | I3278 | Immunological Reagents and Solutions, A Laboratory Handbook | This book provides precise, detailed recipes for the preparation of cellular and molecular reagents commonly used in immunological protocols and which also are increasingly employed in other fields of biological research. All of the reagents and solutions are organized into easily identifiable sections according to the experimental procedures for which they are typically used, e.g., ELISA, Cell Cultures, PCR, Proteins and Buffers. Additionally, a General section contains reagents and solutions commonly used across many experimental areas.
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 | Z730440 | Immunology 7th ed. | Extensively updated, with new contributors, brilliant new illustrations and a wealth of supporting material online, this 7th edition offers you a carefully structured approach to learning the building blocks of the immune system as well as initiation and actions of the immune response. The website which accompanies this text gives access to all the images in the book, up to 20 detailed animation sequences (which link to further supporting text, illustrations, molecular models and video clips), 8 lectures which explain how the immune system responds to different infections or to tissue grafts, and a test bank of 300 USMLE-style questions.
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 | Z374350 | Immunology Methods Manual: The Comprehensive Sourcebook of Techniques Four Volume Set | A four volume set of immunological methods and techniques. Contains both advanced methods and basic protocols which guide day-to-day laboratory work as well as the development of long term strategies. Immunologists, molecular and cellular biologists, microbiologists and virologists will find this work a useful tool.
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| | Z359572 | Immunology in Focus Complete Set (6 Tapes not including Preview Tape): VHS/NTSC | Since it is difficult to communicate such a dynamic subject through the flat, static images available in textbooks, videotapes become an ideal teaching aid. This flexible learning package integrates time-lapse and real-time microscopy with advanced computer graphics.
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 | Z702021 | Immunology, Fifth Edition | New edition of a text that presents an up-to-date introduction to the principles and findings in the field of immunology. Goldsby (Amherst College), Kindt (National Institute of Allergy and Infectious Diseases) and Osborne (U. of Massachusetts) present 23 chapters that discuss introductory material (overview of the immune system, and cells and organs), generation of B-cell and T-cell responses, immune effector mechanisms, and the immune system in health and disease.
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 | Z701327 | Immunology: A Short Course, 5th ed. | This book offers a balanced text that uses both classical and contemporary elements to present basic scientific and clinical perspectives. The text has been revised to reflect recent advances in the field of immunology. Its strength is in its complete coverage of all key topics in modern immunology without excessive detail or theoretical discussion. Each chapter addresses key topics and reinforced them with illustrations. It includes an new chapter on immuno-based therapies and other applications and a rewritten complement chapter.
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 | I7279 | Immunotoxin Methods and Protocols | This book describes methods for developing and applying these proteins. The conjugates created contain entire monoclonal antibodies, single chain antibody fragments, and cytokines as carrier ligands. The toxic portion can include conventional chemotherapeutics as doxorubicin, ribosome-inactivating proteins the ricin A-chain or saporin, or bacterial toxins as diphtheria toxin. Applications include treatment of primary malignant brain tumors, generation of selective brain lesions, and targeting of the AIDS virus.
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| | Z731439 | Janeway’s Immunobiology 7th ed. | The seventh edition guides the reader through the immune system in all its aspects - from the first engagement of innate immunity to the generation of the adaptive immune response and its clinical consequences. It has been comprehensively updated throughout, and includes new information on topics such as NK cells, Toll-like receptors, AID, viral evasins, mucosal immunity, and celiac disease, to name a few. Each copy of the book includes a revised CD-ROM, Immunobiology Interactive, which contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
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 | Z350311 | Leucocyte Antigen: FactsBook, 2nd ed. | This book contains over 130 entries on molecules specifically expressed on the surface of cells of the haematopoietic system including characterized CD antigens, antigen receptors, MHC antigens, adhesion molecules, and cytokine receptors.
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 | Z730378 | Making and Using Antibodies: A Practical Handbook | Written for professionals in the fields of biomedical research, this text uses a cookbook approach to presenting methods for the production, characterization, and use of antibodies. The book focuses on specific aspects of antibodies and takes readers on a step-by-step process from antigen preparation to immunizations, adjuvants, screening, purification, storage, and applications. Introductory material accompanies each chapter, giving readers a better understanding of the methods and applications. It covers basic techniques including enzyme-linked immunosorbent assay (ELISA), Western blotting, immunohistochemistry, and flow cytometry.
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| | M0308 | Manual of Immunological Methods | The Manual of Immunological Methods presents validated assays that are accompanied by a series of tools that will guide readers in performing their own laboratory work. It covers specific methodologies including sample collection, preparation of cells, assay conditions, and data evaluation. Discussion of species differences and comparisons of a wide variety of species is an important feature. Both graduate students and practicing researchers in the areas of immunology and immunotoxicology will appreciate the Manual of Immunological Methods as a guide to standard operating procedures in the laboratory.
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 | M1191 | Molecular Epidemiology: A Practical Approach | This provides an overview of the approaches encompassed by the emerging discipline of molecular epidemiology. Concepts and methods at the forefront of infectious disease studies are discussed along with recent advances in studying host genetics, methods for the detection of mutations and polymorphisms, the relationship between pathologies and immune system genetics, and the use of DNA sequence information to garner insights into the evolution of infectious pathogens. The evolution and function of the immune system and a synopsis of general epidemiological design and analysis are included.
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 | M4559 | Monoclonal Antibodies: A Practical Approach | Considers the preparation, testing, derivation and applications of monoclonal antibodies. New immunological techniques incorporating tried and tested methodologies are described. Both the standard somatic hybridization technique and recombinant techniques are described along with both small and large scale production, purification and labeling. Protocols are given for the use of monoclonal antibodies in rheumatoid arthritis, tissue typing, detecting DNA modified during chemotherapy, and in the clinical analysis of transplantation samples for malignancy
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 | Z364371 | Monoclonal Antibodies: Principles and Applications | This book presents non-specialists with a broad introduction to monoclonal antibodies and their potential as therapeutic agents. Biosafety considerations are also included.
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 | Z373788 | Monoclonal Antibodies: Principles and Practice, 3rd ed. | | pricing |
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 | P2988 | Pharmacology of Cytokines | Modulation of production and action of cytokines has been the object of intense research. This book overviews the field of cytokine research and describes the various approaches that have been taken to develop the pharmacology of these novel mediators. The book in the framework of the immunobiology of cytokines, examines interactions with the cytokine system of a variety of compounds ranging from simple synthetic chemicals to biotechnological products. It analyzes specific contexts for the pathophysiology of these mediators as well as pharmacological approaches for their control.
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 | Z701769 | Practical Flow Cytometry, 4th ed. | The fourth edition of this benchmark text provides a comprehensive resource covering the technology, principles, and biomedical applications of analytical cytology using laser-activated detection and cell sorting. It is updated with several added features, including: a revised introduction, emphasizing connections between flow cytometry, static cytometry, and microscopy; expanded coverage of applications in biotechnology, cell biology, genetics, hematology, immunology, microbiology, and oncology; discussion of new commercial instrumentation; review of alternatives to flow sorting.
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| | P1436 | Practical Guide to Monoclonal Antibodies | This book is designed to provide all the information required to produce monoclonal antibodies and to prepare them for use in a given application. The procedures are dealt with in chronological order from basic tissue culture through antibody characterization, purification and labeling.
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 | R2400 | Recombinant Antibodies | | pricing |
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| | R2267 | Resin Microscopy And On-Section ImmunoCytoChemistry | This manual describes how fixation, resin embedding and immunocytochemistry are interrelated. This book enables non-microscopists to gain a quick grasp of basic principles.
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 | Z705861 | Roitt’s Essential Immunology 11th ed. | Roitt′s Essential Immunology has established itself as the book of choice for students of immunology worldwide. This excellent textbook is commonly regarded as ′the best of the immunology primers′ and the eleventh edition remains at the cutting edge of this fascinating area of science. The trademark of this book is its highly readable introduction to the subject, its emphasis on core knowledge and its excellent four-color artwork. The internationally renowned authors have extensively updated all aspects of the book to produce a new edition, which will be an invaluable resource to students of immunology and medicine. Roitt′s Essential Immunology is supported by a website at <www.roitt.com> This useful on-line resource includes interactive multiple-choice questions with feedback, key concepts explained with animations, further reading lists with PubMed links, and an archive of images from the book.
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 | Z703664 | Short Protocols in Immunology | This is an easy-to use companion to Current Protocols in Immunology. Drawn from the most fundamental and widely used methods in the well-known parent volume, this book provides step-by-step protocols in their most easily accessible format for use at the bench. Immunologists in basic science and clinical work alike will find techniques they rely on, including production, purification, and fragmentation of antibodies; assays for lymphocyte function; measurement of cytokines and cytokine receptors; biochemistry of lymphocyte activation; innate immunity, isolation of human immune cell populations, detection and analysis of HIV, and animal models for a variety of autoimmune and infectious diseases.
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 | A8968 | Using Antibodies: A Lab Manual | Harlow and Lane have revised their guide to the use of immunoglobulin reagents in the laboratory. Chapters have been rewritten, reorganized, and updated to provide background, context and step-by-step instructions. Techniques range from choosing the right antibody and handling it correctly to the proper methods for characterizing antigens in cells and solutions. New chapters on tagging proteins and epitope mapping are included. Rather than presenting an array of solutions for working with antibodies and antigens, this title instead identifies in each case the best approach to specific problems.
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 | Z705896 | Vaccine Adjuvants: Immunological and Clinical Principles | A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.
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| | Z379964 | Weir’s Handbook of Experimental Immunology, 5th ed. Complete on CD-ROM | An exhaustive compilation of information and experimental protocols on the immune system and how it works, and on immunological methods used in other disciplines. Hundreds of experts on aspects of immunochmistry have been enlisted as contrbutors. Only a hint of the breadth of coverage can be given here. Volume 1: Immunochemistry and molecular biology. Volume 2: Cell surface and messenger molecules of the immune system. Volume 3: The Lymphoids system. Volume 4: The integrated immune system.
Select either the printed volumes or the complete edition on CD-ROM.
Includes all the material found in the four-volume printed set; some material that was omitted in print because of length is included here. The extensive indexing and cross-referencing that makes electronic publications so valuable is very much in evidence. System requirements: Windows 3.1/95 or Macintosh System 7.1; 256-color monitor.
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