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Z282626
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Advanced Asymmetric Synthesis
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Asymmetric synthesis is one of the most critical strategic subjects in organic chemistry, and this book describes advanced techniques and their applications to the industrial and laboratory synthesis of important chiral molecules. The international team of highly respected authors provide rigorous and concise reviews of their areas of expertise.
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Z536741
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Advanced Organic Chemistry, 4th ed. Part A: Structure and Mechanisms
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Part A emphasizes quantitative and qualitative description of structural effects on reactivity and mechanism. The Fourth Edition provides updated material but continues the essential elements of the previous edition. The material in Part A is organized on the basis of fundamental structural topics such as structure, stereochemistry, conformation and aromaticity and basic mechanistic types. The material in Part B is organized on the basis of reaction type with emphasis on reactions of importance in laboratory synthesis. The two parts stand alone, although there is considerable cross-referencing. This edition updates certain topics that have advanced rapidly in the decade, including computational chemistry, structural manifestations of aromaticity, enantioselective reactions and lanthanide catalysis.
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Z250368
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Asymmetric Catalysis In Organic Synthesis
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Deals with basic principles of asymmetric catalysis focusing on its synthetic significance. Covers homogeneous asymmetric hydrogenation, asymmetric catalysis via chiral metal complexes, heterogeneous catalysis and non-organometallic catalysis. The collection of a range of stereoselective reactions illustrate various strategies and methodologies as well as their general utility.
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Z271497
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CRC Handbook Of Organic Photochemistry And Photobiology
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With emphasis on the synthetic value of photochemistry, the text details the advantages of photochemistry over conventional thermal methods. Reactions classified by chromophore for easy access to data.
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Z278572
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Carbohydrate Building Blocks
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Serves as a valuable reference for synthetic organic chemists in search of starting materials for synthesizing chiral compounds. The book points out which carbohydrates are best used, and how to get them. Half of the book is a dictionary-like list of compounds that can be prepared form commercially cheap carbohydrates. The other half describes which carbohydrates are commercially available inexpensively and the chemistry that can be used to convert them into useful building blocks.
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Z251941
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Catalysis Of Organic Reactions by Supported Inorganic Reagents
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The book will provide an up-to-date guide and review on a new form of heterogeneous catalysis which will prove to be increasingly important to the chemical industry in the light of new and future environmental legislation. The book will highlight chemical processes where present technology is likely to prove increasingly unacceptable due to associated problems of hazardous waste and/or low process efficiency. It′s purpose is to reveal these problems and possible solutions and to introduce the readers to this new form of catalysis. It will prove to be especially important to fine/speciality/intermediate chemicals manufacturing companies who have little experience of heterogenous catalysis and to researchers interested in chemical aspects of ′Clean Technology′. The book will help to disclose the opportunities for researchers and companies in developing new ′environmentally friendly′ chemical processes
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Z288195
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Chemical Aspects of Drug Delivery Systems
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From Book News, Inc. The April 1996 proceedings address the challenges of developing drugs with delivery systems that target the correct organ and achieve the necessary level of drug in the body. New materials and systems for drug delivery targeting are reviewed in the 15 presentations, including aspects of bioadhesive polymers, novel nonionic surfactant vesicles, hydrogels based on poly(ethylene glycols), monofunctional poly(ethylene glycol), and aqueous shellac solutions. Annotation c. by Book News, Inc., Portland, Or.
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Z250813
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Chemical Bonding In Solids And Fluids
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Written by a highly-regarded scientist and teacher, this book examines and discusses the nature of and properties associated with interatomic and intermolecular forces in solids and fluids. All discussions feature mathematical treatments accessible to chemistry students. Provides stereoscopic diagrams of three-dimensional structure; covers computer methods, where appropriate; classifies and discusses solids in terms of bond type; considers liquid structure and properties . For students in chemistry, chemical physics, and biochemistry.
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Z256498
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Chemistry Of Organic Fluorine Compounds: A Critical Review
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Provides complete coverage of the chemistry of organic fluorine compounds. Topics include fluorinating agents, fluorination processes, reactions of fluorinated compounds, modern analytical methods, and properties and applications of fluorinated compounds. Offers a critical review of the literature and provides over 4,500 references.
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Z402133
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Chemistry and Technology of Isocyanates
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Chemistry and Technology of Isocyanates is a comprehensive book on isocyanate chemistry and technology. It highlights the industrial applications of diisocyanates in the manufacture of flexible and rigid foams, elastomers, coatings and adhesives; discusses ionomers used in water-based coatings, polymer networks and biomedical polymers; and reviews current and future environmental issues, including toxicity and safe handling of isocyanates, recycling of isocyanate derived polymers and monomers derived from natural products.
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Z273694
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Chiral Auxiliaries and Ligands in Asymmetric Synthesis
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Chiral molecules are molecules that come in left and right handed forms - they are mirror images of each other and behave differently in the body. This important book show chemists how to prepare chiral molecules to get the desired form. Presents an overview of the chiral auxiliaries, reagents and catalysts used in synthesis. Covers underlying principles.
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Z287555
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Chirality in Industry II: Developments in the Commercial Manufacture and Applications of Optically Active Compounds
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This second volume of Chirality in Industry contains new case histories from a wide range of contributors from industry or with strong industrial connections. While it is intended that the new volume will stand on its own, Volumes I and II taken together present an up-to-date and comprehensive picture of the technologies required to produce optically active compounds on a multi-kilogramme to high tonnage scale as well as illustrating the breadth of application of these technologies; the pharmaceuticals, agrochemicals, electronics, food, flavour and fragrance industries are all represented. • All new case histories • Unique industrial perspective on chiral technology • Emphasis on scale-up and process development • Comparison of biocatalysis, asymmetric synthesis and classical resolution approaches The chiral infrastructure is now largely in place and there is no reason why large-scale production should not be possible for even moderately priced single enantiomer products. The successful industrial application of chiral chemistry depends on the integration of a range of supporting technologies and there are many examples in this volume of how widely the industrial practitioner must cast the net to achieve practical production methods. As with Volume I, this new volume is of particular interest to those professionally involved in the scale-up processes for single enantiomers. However, students and researchers involved in a more academic pursuit of optical activity will also benefit from some of the facets of large-scale thinking. An economic solution is still most likely to be a simple, elegant solution.
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Z701610
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Classics in Total Synthesis II: More Targets, Strategies, Methods includes CD with useful teaching material for lecturers
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Classics in Total Synthesis II is the long awaited sequel to Classics in Total Synthesis, a book that has made its mark as a superb tool for educating students and practitioners alike in the art of organic synthesis since its introduction in 1996. In this highly welcomed new volume, K. C. Nicolaou and Scott A. Snyder discuss in detail the most impressive accomplishments in natural product total synthesis during the 1990s and the first years of the 21st century.
While all of the features that made the first volume of Classics so popular and unique as a teaching tool have been maintained, in this new treatise the authors seek to present the latest techniques and advances in organic synthesis as they beautifully describe the works of some of the most renowned synthetic organic chemists of our time.
• Develops domino reactions, cascade sequences, biomimetic strategies, and asymmetric catalysis are systematically through the chosen synthesis • Discusses the latest synthetic technologies in terms of mechanism and scope • Includes new reactions, such as olefin metathesis, in mini-review style • Abundant references for further reading • CD with useful teaching material for lecturers
Graduate students, educators, and researchers in the fields of synthetic and medicinal chemistry will wish to have a copy of this book in their collection as an indispensable companion that both augments and supplements the original Classics in Total Synthesis.
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Z233765
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Compendium Of Organic Synthetic Methods Vol. VII
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Each updated volume presents the latest synthetic methods for the preparation of mono- and difunctional compounds.
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Z271721
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Compendium Of Organic Synthetic Methods Vol. VIII
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Each updated volume presents the latest synthetic methods for the preparation of mono- and difunctional compounds. Featuring 1,200 more entries than its predecessor, Volume 8 covers functional group transformations and carbon-carbon bond forming reactions appearing in the literature from 1990 through 1992. It presents approximately 1,400 examples of published reactions for the preparation of monofunctional compounds and approximately 1,640 examples of reactions that prepare difunctional compounds with various functional groups. It also features 60 more reviews than Volume 7.
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Z731331
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Comprehensive Organic Reactions in Aqueous Media 2nd ed. provides the most comprehensive coverage of aqueous organicreactions available
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An extensive update of the classic reference on organic reactions in water. More than forty percent of this extensively updated second edition covers new reactions.
For ease of reference, it is organized by functional groups.
A core reference: • Provides the most comprehensive coverage of aqueous organicreactions available • Covers the basic principles and theory and progresses to applications • Provides examples of applications in industry • Includes alkanes, alkenes, aromatics, electrophilic substitutions, carbonyls, alpha, beta-unsaturated carbonyls, carbon-nitrogen bonds, organic halides, pericyclic reactions, photochemical reactions, click chemistry, and multi-step syntheses
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Z248452
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Cyclization Reactions
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• Covers the basic principles of cyclization chemistry, emphasizing practical applications • Summarizes various methodologies used in cyclization reactions • Extensive use of equations, schemes, tables, and figures enables quick understanding of the material • Convenient selection of reactions and conditions in synthesis • More than 2,600 structures illustrate key concepts Cyclization Reactions provides a quick update of the latest advances in cyclization reactions. It covers the basic principles of cyclization chemistry, emphasizing practical applications. Chapters are organized according to the different cyclization intermediates-cationic, radical, anionic, and metal complex intermediates. The last chapter covers macrolactonization, vicinal tricarbonal, and Bergman (enediyne) reactions, which are of particular interest today. More than 2,600 structures illustrate key concepts throughout the book. Various cyclizations are organized into mechanistic groups to help researchers choose and change between methods when searching for maximum efficiency in synthesis. Critical coverage of the literature up to 1992 is provided. Cyclization Reactions is essential reading for anyone involved in the synthesis of ring compounds or who is seeking a rapid overview of the field. Newcomers as well as experienced researchers will benefit from this book. It also is excellent reference material for students at the advanced undergraduate and graduate levels.
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Z703362
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Dead Ends and Detours: Direct Ways to Successsful Total Synthesis pkg of 1 ea
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In almost all publications, the valuable information provided is almost always based on successful organic reactions. However, a chemist′s life is not that easy. Trial and error is still one of the most commonly used methods. Thus it would be useful to have access to those syntheses that do not work, since they also provide important results of great importance for further synthesis. This book fills just such a gap. Using major total syntheses, the authors explain a variety of problems and recommend ways out of such dilemmas: Problems at the start and end of a synthesis, difficult and unexpected reactivities of functional groups, problems due to steric properties and much more. The result is a wealth of information for any organic chemist and an essential tool for successful total synthesis.
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Z282588
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Dendritic Molecules: Concepts, Syntheses, Perspectives
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Spans organic chemistry and more application-orientated disciplines like material science and pharmaceutical chemistry. The excellent, detailed list of references further increases the value of the book. The optimal presentation of the structural formulas of dendrimers - highly symmetrical giant molecules - helps the reader understand the sophisticated synthesis quickly.
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Z730009
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Domino Reactions in Organic Synthesis pkg of 1 ea
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Domino reactions enable you to build complex structures in one-pot reactions without the need to isolate intermediates- a dream comes true. In this book, the well-respected expert, Professor Lutz Tietze, summarizes the possibilities of this reaction type - an approach for an efficiant, economically benificial and ecological benign synthesis. A definite must for every organic chemist.
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Z235776
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Electron Flow in Organic Chemistry
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With the goal of helping students develop a good intuition for organic chemistry, it approaches the material from a mechanistic viewpoint. Presents twenty electron flow pathways as the building blocks of all the common mechanistic processes. Thus, students deal with a smaller number of reactant classes instead of studying each reaction as a separate case. Uses physical models such as energy surfaces to aid the decision-making process; includes a unique chapter that teaches students how to make a multivariable decision; and contains advanced explanations using interaction diagrams and molecular orbital theory.
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Z248053
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Encyclopedia of Reagents for Organic Synthesis, 8-volume set
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This essential reference contains an authoritative and systematic description of the use of all reagents in organic chemistry. It includes approximately 3500 alphabetically arranged articles, a comparison of reagents with others capable of similar chemistry, a pro and con assessment for each reagent, extensive cross-referencing and substantial subject and molecular formula indexes.
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Z208981
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Fiesers’ Reagents for Organic Synthesis Collective Index for volumes 1-12
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The popular Fieser and Fieser series on reagents for organic synthesis provides concise descriptions, good structural formulas and selected examples of applications--providing references to new reagents as well as to reagents included in previous volumes. Thousands of entries abstract the most important information on commonly used and new reagents, including preparation, uses, sources of supply, critical comments, references and more. The reagents are considered in alphabetical order by common usage names
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Z208973
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Fiesers’ Reagents for Organic Synthesis Volume 15
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The popular Fieser and Fieser series on reagents for organic synthesis provides concise descriptions, good structural formulas and selected examples of applications--providing references to new reagents as well as to reagents included in previous volumes. Thousands of entries abstract the most important information on commonly used and new reagents, including preparation, uses, sources of supply, critical comments, references and more. The reagents are considered in alphabetical order by common usage names Thousands of entries abstract the most important information on commonly used reagents. Every reagent discussed includes the preparation, uses, sources of supply, critical comments, references, and more.
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Z233773
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Fiesers’ Reagents for Organic Synthesis Volume 16
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The popular Fieser and Fieser series on reagents for organic synthesis provides concise descriptions, good structural formulas and selected examples of applications--providing references to new reagents as well as to reagents included in previous volumes. Thousands of entries abstract the most important information on commonly used and new reagents, including preparation, uses, sources of supply, critical comments, references and more. The reagents are considered in alphabetical order by common usage names Thousands of entries abstract the most important information on commonly used reagents. Every reagent discussed includes the preparation, uses, sources of supply, critical comments, references, and more.
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Z252808
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Fiesers’ Reagents for Organic Synthesis Volume 17
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From reviews of previous volumes: ""highly recommended"lots of succinct, practical information on recent developments"in a format that is easy to use. The reagents are taken up in alphabetical order (common usage names, not CAS indexing code names), sometimes several to a page, sometimes several pages to a reagent. One can expect to find how to make the reagent (in loose terms), or where it can be bought, what it is good for, and where to seek complete details"As with previous volumes, one can profit from just browsing, even if one does not feel a need to look up any particular subject. It is thus a secondary function of the book to help one keep abreast of the field, and it would be a rare chemist who would not learn something new and useful from a casual perusal of the pages." "Journal of the American Chemical Society The popular Fieser and Fieser series on reagents for organic synthesis provides concise descriptions, good structural formulas and selected examples of applications--providing references to new reagents as well as to reagents included in previous volumes. Thousands of entries abstract the most important information on commonly used and new reagents, including preparation, uses, sources of supply, critical comments, references and more. The reagents are considered in alphabetical order by common usage names
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Z421642
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Fiesers’ Reagents for Organic Synthesis Volume 19
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The popular Fieser and Fieser series on reagents for organic synthesis provides concise descriptions, good structural formulas and selected examples of applications--providing references to new reagents as well as to reagents included in previous volumes. Thousands of entries abstract the most important information on commonly used and new reagents, including preparation, uses, sources of supply, critical comments, references and more. The reagents are considered in alphabetical order by common usage names
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Z510696
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Fiesers’ Reagents for Organic Synthesis Volume 20
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One can expect to find how to make the reagent (in loose terms), or where it can be bought, what it is good for, and where to seek complete details. As with previous volumes, one can profit from just browsing, even if one does not feel a need to look up any particular subject. It is thus a secondary function of the book to help one keep abreast of the field, and it would be a rare chemist who would not learn something new and useful from a perusal of the pages. The popular Fieser and Fieser series on reagents for organic synthesis provides concise descriptions, good structural formulas and selected examples of applications--providing references to new reagents as well as to reagents included in previous volumes. Thousands of entries abstract the most important information on commonly used and new reagents, including preparation, uses, sources of supply, critical comments, references and more. The reagents are considered in alphabetical order by common usage names
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Z268305
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Fluorine Chemistry: A Comprehensive Treatment
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The newest in a series of carefully selected reprint volumes from the Kirk-Othmer Encyclopedia of Chemical Technology, this work presents readers with an easily accessible desk-reference on fluorine compounds.
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Z273686
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Free Radicals In Organic Chemistry
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Illustrious researchers offer an excellent introduction to the structure, formation and reactivity of free radicals. Contains a complete overview of the numerous and varied applications of free radicals within organic chemistry with special attention to reaction mechanisms and novel responses. Includes detailed accounts along with actual examples of the most recent developments in the field.
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Z730653
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Green Chemistry and Engineering M. Doble and M. Kumar, Elsevier, 2007, 344 pp., hard cover
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Green Chemistry is the utilization of a set of principles that reduces or eliminate the use or generation of hazardous substances in design of chemical processes. Due to extravagant costs needed to managing these wastes, tens of billions of dollars a year, there is a need to propose a way to create less waste. Emission and treatment standards continue to become more stringent, which causes these costs to continue to escalate. This book describes both the science (theory) and engineering (application) principles of Green Chemistry that lead to the generation of less waste. It explores the use of milder manufacturing conditions resulting from the use of smarter organic synthetic techniques and the maintenance of atom efficiency that can temper the effects of chemical processes. By implementing these techniques means less waste, which will save industry millions of dollars over time.
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Z261777
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Handbook Of Organic Solvents
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Presents important information about more than 550 organic compounds that are used as solvents. Includes name, synonyms, molecular formula, CAS Registry Numbers, and useful data for all of the compounds. Health hazards and safety guidelines also discussed.
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Z704520
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Handbook of Fluorous Chemistry J. Gadysz. D Curran and I. Horvath, ed., John Wiley & Sons, 2004, 624 pp., hard cover
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This handbook is the first to summarize all the essential aspects of this emerging field of chemistry. Whether the reader is seeking an introduction to the concept of fluorous biphase catalysis, summaries of partition coefficients involving fluorous and organic solvents, or information on the latest fluorous mixture separation techniques, this authoritative compilation provides key information needed for successfully working with the diverse and fascinating families of fluorous molecules. The large number of reliable experimental procedures in particular makes this the ideal guide for newcomers wanting to use this elegant method in the laboratory.
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Z338249
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Handbook of Reagents for Organic Synthesis, 4 volume set A.J. Pearson, John Wiley & Sons, Ltd, 1999, 2364 pp., hard cover
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Consisting of four volumes, the Handbook of Reagents includes over 500 reagents selected from the Encyclopedia of Reagents for Organic Synthesis. Each volume is self-contained and focuses on a different class of reagents, chemical substances useful for producing a chemical reaction. This current volume outlines acidic and basic reagents. Detailed physical and chemical data is provided so the reader will understand the exact use for a reagent and work with it properly. Adopting the basic format and size of the original Encyclopedia, each volume contains an introduction, an alphabetical arrangement of reagents as well as author and subject indexes.
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Z338222
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Handbook of Reagents for Organic Synthesis: Oxidizing and Reducing Agents S. Burke, ed., John Wiley & Sons, Ltd, 1999, 564 pp., hard cover
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One of four self-contained handbooks derived from the renowned Encyclopedia of Reagents for Organic Synthesis, this volume focuses on oxidizing and reducing agents for organic synthesis. It follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents. It also provides physical and detailed chemical data for every reagent, helping chemists in diverse disciplines understand what the reagents are used for and how to work safely with them.
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Z730238
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Handbook of Reagents for Organic Synthesis: Reagents for Direct Functionalization of C-H Bonds P. Fuchs, John Wiley & Sons, 2007, 424 pp., hard cover
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A concise and informative collection of articles on the synthesis of organic, biological and medicinal materials. Key Features: • Detailed information on 200 reagents to be used for the functionalization of C-H bonds in the carbon backbone of organic molecules • A systematic approach to the use of organometallic compounds in organic synthesis • Articles will stress chemical aspects such as yield, conversion, specifity [enantio, stereo, regio, chemo], and where applicable, catalyst loading/turnover
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Z704687
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Handbook of Reagents for Organic Synthesis: Reagents for Glycoside, Nucleotide and peptide Synthesis D. Crich, ed., John Wiley & sons, 2005, 786 pp., hard cover
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This handbook collects together short, informative articles on approximately 250 of the most widely used reagents in the field, into a single volume. Each of the articles, drawn from the e-EROS database, contains a summary of the most pertinent reactions for every reagent, with references to the original literature. This handbook compiles all the essential reagents for syntheses on and with biomolecules; and gives key information on protection, bond formation and deprotection. An essential resource for all synthetic chemists working in drug development and medicinal chemistry and makes use of the leading reagent database e-EROS
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Z704032
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Handbook of Reagents for Organic Synthesis: Reagents for high Throughput Solid Phase and Solution Phase Organic Synthesis P. Wipf, ed., John Wiley & sons, 2005, 392 pp., hard cover
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Since its discovery in 1963 by R. B. Merrifield, solid-phase synthesis, or polymer-supported synthesis, has become an essential technique with its wide use in the synthesis of peptides and other oligomers. Solid-Phase Reactions provides extensive and comprehensive information on this form of synthesis in a format ideal for those working in the laboratory. As part of the Handbook of Reagents in Organic Synthesis Series, this new addition extends the wealth of information available to the chemist at the bench. All content has been expertly collected and presented by an internationally recognised editorial board.
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Z238813
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Homogeneous Catalysis, 2nd ed.
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Contains a balanced discussion of homogeneous catalytic reactions that are used in industry, featuring every documented example employed in a current commercial process, or that have a broad application in the organic synthesis laboratory. Incorporates synthesis with chiral catalysts in chapters on hydrogenation, CO chemistry and olefin oxidation. New additions include Tennessee Eastman′s coal-based acetic anhydride plant and IFP′s Dimersol process for dimerizing propylene as well as major changes in the areas on pharmaceuticals, flavors, fragrances, agricultural and electronic chemicals.
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Z286273
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Industrial Organic Chemicals
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This book provides a comprehensive overview of the raw materials, intermediaries, processes, and technologies used in manufacturing organic chemicals. Coverage is based on the seven key raw materials which are derived from petroleum and natural gas, but also includes less common processes which give rise to profitable specialty products.
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Z271748
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Logic Of Chemical Synthesis 2nd ed.
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This book provides a detailed description of the general principles and strategies for solving chemical synthesis problems of complex organic molecules. It is the only book to deal systematically with the fundamental principles of synthetic problem solving.
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Z705950
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March’s Advanced Organic Chemistry, 6th ed. M. Smith, John Wiley & Sons, 2006, 2528 pp., hard cover
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The Sixth Edition clearly explains the theories and examples of organic chemistry, providing the most comprehensive textbook in organic chemistry available. Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. The Sixth Edition carries on the tradition of excellence with such new features as: • More than 25,000 references to the literature to facilitate further research • Revised mechanisms, where required, that explain concepts in clear modern terms • Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries • A revised Appendix B to facilitate correlating chapter sections with synthetic transformations
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Z703435
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Metal Catalyzed Cross-Coupling Reactions, 2nd Completely revised edition A. de Meijere and F. Diedrich, ed., John Wiley & Sons, 2004, 938 pp., hard cover
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In this second edition, the editors bring together in two comprehensive volumes everything of importance related to C-C and C-N cross-coupling reactions. The range of applications covered extends from the synthesis of complex natural materials via supramolecular chemistry right up to materials science. Internationally renowned experts pass on to the reader the current level of knowledge, while critical analyses of the latest developments and applications allow users to quickly decide for themselves on which strategies are available for solving their synthesis problems. In particular the experimental guidelines for key reactions developed by the authors for the widest possible range of applications testify to the practical advantages this handbook offers every organic chemist.
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Z731145
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Methods and Reagents for Green Chemistry P. Tundo, et al., ed., John Wiley & sons, 2007, 314 pp., hard cover
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This book aims to stimulate and promote the wide-ranging aspects of green chemistry and its major role in ensuring sustainable development. It covers the following areas: green chemistry; green reagents and atom economy; safeguarding the atmosphere; industrial green catalysis; alternative reaction conditions; biocatalysis and green chemistry. This book is based on the third edition of the Collection of Lectures of the Summer Schools on Green Chemistry held in Venice, Italy in the summers of 1998-2003.
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Z704210
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Name Reactions and Reagents in Organic Chemistry, 2nd ed. the premier name resource in the field
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This Second Edition is the premier name resource in the field. It provides a handy resource for navigating the web of named reactions and reagents. Reactions and reagents are listed alphabetically, followed by relevant mechanisms, experimental data (including yields where available), and references to the primary literature.
The text also includes three indices based on reagents and reactions, starting materials, and desired products. Organic chemists working in academia, industry, government, and other laboratories, will all find this book to be an invaluable reference.
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Z731277
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Name Reactions for Functional Group Transformations provides all the detailed information that researchers need
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This practical, well-organized reference delves deeply into functional group transformations, to provide all the detailed information that researchers need. Topics are organized into the following sections: oxidation, reduction, asymmetric synthesis, and functional group manipulations.
Each section includes a description of the functional group transformation, the historical perspective, mechanisms, variations and improvements on the reaction, synthetic utilities and applications for the reaction, experimental details, and references to the primary literature. Contributors are well-known and respected for their work on the specific name reactions.
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Z703125
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Name Reactions in Heterocyclic Chemistry this book provides a one-stop repository for this important field of organic chemistry
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The chemistry of heterocyclic compounds and methods for their synthesis form the bedrock of modern medicinal chemical and pharmaceutical research. This book provides a one-stop repository for this important field of organic chemistry.
The primary topics include three- and four-membered heterocycles, five-membered heterocycles including indoles, furans, thiophenes, and oxazoles, six-membered heterocycles including quinolines, isoquinolines, and pyrimidines, and other heterocycles.
Each name reaction is summarized in seven sections: Description; Historical perspective; Mechanism; Variations and improvements; Synthetic utility; Experimental; and References.
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Z209015
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Organic Chemistry of Drug Synthesis Volume 4
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This series is a guide to virtually all syntheses used in the preparation of compounds given generic names.
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Z253367
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Organic Chemistry of Drug Synthesis Volume 5
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This series is a guide to virtually all syntheses used in the preparation of compounds given generic names.
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Z569801
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Organic Chemistry, 10th Edition emphasizes the relationship between structure and reactivity
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A central theme of the authors’ approach to organic chemistry is to emphasize the relationship between structure and reactivity. To accomplish this, the text is organized in a way that combines the most useful features of a functional group approach with one largely based on reaction mechanisms.
The authors’ philosophy is to emphasize mechanisms and their common aspects as often as possible, and at the same time to use the unifying features of functional groups as the basis for most chapters. The structural aspects of the authors’ approach show students what organic chemistry is. Mechanistic aspects of their approach show students how it works. And wherever an opportunity arises, the authors’ show students what it does in living systems and the physical world around us.
In the 10th edition, virtually every aspect of the teaching and learning solution has been revisited and redesigned to assist students in comprehending the fundamentals of organic chemistry. The authors’ thoroughly explain and illustrate each new idea when it is first introduced and then reinforce the new idea or concept by having students work related problems.
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Z289434
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Organic Reaction Mechanisms 1995
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Surveys research on organic reaction mechanisms as described in the literature. This annual series on organic reaction mechanisms research provides concise, comprehensive coverage of the year′s literature as well as discussions of important results. The present volume either discusses or lists all published work dated from December to November inclusive, that deals significantly with any aspect of organic reaction mechanisms.
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Z404950
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Organic Reactions in Aqueous Media
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Rather than using hazardous substances, chemists are now looking to using water as a solvent in synthesis. This book provides readers with a general understanding of the current thinking in the field, from basic theory to synthetic application. It presents information necessary for designing efficient synthesis using water.
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Z204811
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Organic Reactions Volume 36
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Nitrone Olefin Cycloaddition Presents critical discussions of widely used organic reactions from a preparative view point.
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Z204846
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Organic Reactions Volume 37
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Chiral Synthons Presents critical discussions of widely used organic reactions from a preparative view point.
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Z221678
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Organic Reactions Volume 40
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Pauson-Khand Cycloaddition Reaction. Presents critical discussions of widely used organic reactions from a preparative view point.
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Z224103
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Organic Reactions Volume 41
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Divinylcylopropane--Cycloheptadiene Rearrangement Presents critical discussions of widely used organic reactions from a preparative view point.
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Z234311
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Organic Reactions Volume 42 Birch Reduction
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Presents critical discussions of widely used organic reactions from a preparative view point.
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Z243957
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Organic Reactions Volume 43
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Carbonyl Methylenation Presents critical discussions of widely used organic reactions from a preparative view point.
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Z245658
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Organic Reactions Volume 44 Unsaturated Carbonyl Compounds
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Presents critical discussions of widely used organic reactions from a preparative view point. Unsaturated Carbonyl Compounds
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Z251666
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Organic Reactions Volume 45
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Nazarov Cyclization Presents critical discussions of widely used organic reactions from a preparative view point.
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Organic Reactions Volume 46
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Presents critical discussions of widely used organic reactions from a preparative view point. Tin (II) Enolates .
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Organic Reactions Volume 47
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Lateral LIthiation Reactions Presents critical discussions of widely used organic reactions from a preparative view point.
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Organic Reactions Volume 48
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Asymmetric Epoxidation Presents critical discussions of widely used organic reactions from a preparative view point.
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Organic Reactions Volume 49
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Presents critical discussions of widely used organic reactions from a preparative view point. Vilsmeier Reaction
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Organic Reactions Volume 50
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Presents critical discussions of widely used organic reactions from a preparative view point. Stille Reaction
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Organic Reactions Volume 51
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Asymmetric Aldol Reactions Presents critical discussions of widely used organic reactions from a preparative view point.
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Z400947
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Organic Syntheses via Boranes Vol. 1, H.C.Brown
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Reprint of H.C. Brown′s 1975 title containing a detailed discussion of organoboranes in organic synthesis.
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Z400955
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Organic Syntheses via Boranes Vol. 2, H.C. Brown
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Provides an account of recent developments in organoborane chemistry. Topics include Hydroboration with Borane, and with Borane Derivatives, Organoborane Conversions to Functional Groups, and Carbon-Carbon Bond Formation via Organoboranes. Each survey chapter is followed by a chapter providing detailed experimental procedures.
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Z209031
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Organic Syntheses, 2nd ed. Collective Volume 7
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Volumes 60-64 Reflecting the increased pace of research and the many recent advances in organic chemistry, this series serves as a single-source compendium of the most up-to-date and significant procedures currently in use.
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Z244007
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Organic Syntheses, 2nd ed. Collective Volume 8
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Volumes 65-69 Reflecting the increased pace of research and the many recent advances in organic chemistry, this series serves as a single-source compendium of the most up-to-date and significant procedures currently in use.
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Z220965
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Organic Syntheses, 2nd ed. Reaction Guide
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Z253456
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Organic Synthesis, Volume 71
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Consists of 30 checked and edited experimental procedures that illustrate new synthetic techniques or describe the preparation of particularly useful chemicals. Features procedures exemplifying important methods for preparing enantiomerically pure substances by asymmetric catalysis; details a reliable zirconium-based process for the coupling of alkynes and enones; concludes with the preparation of four useful starting materials. A section on waste disposal information is included.
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Z233927
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Oxford Chemistry Primers No. 1, Organic Synthesis: The Roles of Boron and Silicon
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Compounds of boron and silicon play a vital role in organic synthesis and the study of their properties and reactions is an important feature of undergraduate courses in organic chemistry. As part of the new, user-friendly Oxford Chemistry Primer Series, the essential chemistry of organoboranes and organosilanes is presented here with clarity and simplicity, emphasizing how these compounds can be used to provide simple solutions to a range of synthetic problems. With helpful study questions at the end of each part, and many suggestions for more advanced reading, this concise text provides undergraduates with an invaluable summary of an important topic in synthetic organic chemistry.
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Z245682
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Oxford Chemistry Primers No. 10: Mechanisms of Reactions at Transition Metal Sites
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Understanding the mechanisms of the reactions at transition metal sites is a key component in designing synthetic methods, developing industrial homogeneous catalysts, and investigating metalloenzymes. These mechanisms are therefore an essential part of undergraduate chemistry courses. This primer provides a broad-based, systematic guide to the fundamentals of transition-metal mechanistic chemistry, including substitution, electron transfer, and reations of ligands. It serves as an ideal text for undergraduate students with a foundation in basic inorganic chemistry but who are new to inorganic reaction mechanisms
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Z250848
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Oxford Chemistry Primers No. 11: Applications of Artificial Intellegence in Chemistry
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Artificial intelligence is not just about making machines think; it is also a powerful problem-solving tool. Many scientific problems can be solved only with difficulty using conventional methods, yet these same problems may be ideally suited to attack using artificial intelligence. This book, for college-level students in any science discipline, introduces these intriguing and powerful techniques, and discusses their growing impact upon science
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Z250856
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Oxford Chemistry Primers No. 12: Organometallics 1 Complexes with Transition Metal-Carbon Sigma Bonds
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The field of organometallic chemistry has seen explosive growth over the last forty years. On a fundamental level, new structural and bonding concepts have been discovered, while applications range from catalysis to new synthetic methods. This succinct text outlines the main classes of transition metal organometallic complexes and introduces the reader to the chemistry of compounds with metal-carbon bonds: metal carbonyls, metal alkyls, and metal alkylidenes and alkylidynes. The synthetic methods leading to each class of compounds are illustrated with pertinent examples, followed by the discussion of characteristic structures and reactivity patterns. The book stresses general principles and relates the material to specific applications such as catalytic processes. This book is ideal for supplying a quick overview of the discipline to students of chemistry
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Z251585
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Oxford Chemistry Primers No. 13: Organometallics 2: Complexes with Transition Metal-Carbon Pi-Bonds
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The interaction of transition metals with unsaturated molecules has led to fundamental insights in the nature of the chemical bond which, in turn, has provided the basis of important present-day applications such as transition metal mediated synthesis or homogeneous and heterogeneous catalysis. This slim volume outlines the chemistry and discusses the bonding in of some of the most important classes of organometallic compounds: the complexes of transition metals with Pi-ligands such as alkenes, alkynes, arenes, and cyclopentadienyl and allyl ligands. The material covered follows on from Organometallics I which covers the chemistry of complexes with metal-carbon delta-bonds. Synthetic and reactivity aspects of each class of compounds are illustrated with pertinent examples from the recent chemical literature. Highlighted excursions relate the fundamental chemistry to current synthetic or catalytic applications. Undergraduates, graduate students and lecturers will find this book to be a wonderful resource.
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Z251607
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Oxford Chemistry Primers No. 14: Cluster Molecules of the p-Block Elements
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This concise text is the first to survey clusters of the elemental state (P4 and C60) as well as compounds, including boranes, cubanes, etc. The text is a balanced survey with worked examples. Graduate chemistry students working with main group and cluster chemistry courses will find it indispensable
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Z251615
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Oxford Chemistry Primers No. 15: Chemical Bonding
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This short text is intended for first year undergraduates and introduces some concepts of chemical bonding in a clear, descriptive and essentially non-mathematical fashion. The text will find a place alongside textbooks containing more detailed formal coverage and mathematical descriptions. This book could form the basis of an introductory course on chemical bonding. The book addresses aspects of atomic orbital structure and uses this to develop a discussion of the bonding in diatomic and polyatomic molecules using Lewis dot structures, hybrid orbital, and molecular orbital methods. The prediction of molecular shape is addressed through the VSEPR method. It is valuable for students in first-year chemistry courses, as well as non-chemistry students requiring a readable introduction to chemical bonding.
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Z251623
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Oxford Chemistry Primers No. 16: Periodicity and the p-Block Elements
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The chemistry of the p-block elements is extremely diverse and is often viewed by students as a subject of daunting vastness. This text shows students that most, if not all, of the basic knowledge needed to master the subject can be made more manageable if a number of general principles are understood. The text begins with an introduction to the electronic structures of atoms and shows how a general understanding of those structures is useful in comprehending why the periodic table has the form that it does. The periodic aspects of element properties such as ionization energies and electronegativity are covered and are used to understand the diverse physical nature of p-block elements themselves. A survey of physical properties of p-block element compounds is also included, providing a basis for understanding the nature of the compounds which the p-block elements form between themselves. The text concludes with an account of structural trends and of periodic trends in acidity and basicity. Throughout the text suitable examples are chosen to illustrate the concepts involved.
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Z251631
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Oxford Chemistry Primers No. 17: Bifunctional Compounds
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Most important organic molecules contain more than one functional group, and very often the interaction between these groups determines the chemical and biological behaviour of the compounds. This concise text outlines some of the methods used to prepare bifunctional compounds and then surveys the chemistry of some of the more important classes. Problems - with solutions - and suggestions for further reading are provided, and students who are familiar with the reactions of monofunctional compounds will find this text an invaluable introduction to the more advanced aspects of organic chemistry.
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Z252085
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Oxford Chemistry Primers No. 18: Oscillation, Waves and Chaos in Chemical Kinetics
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The phenomena of oscillations, travelling waves, and chaos in reacting chemical systems began as curiosities but now support an active, international research field. This book shows how these "exotic" patterns arise from the underlying chemical mechanisms. The origin of"chemical feedback" is revealed using three example reactions: the isolate-reductant (Landolt) reaction, the Belousov-Zhabotinsky reaction, and the combustion of hydrogen. Thermal feedback is also discussed. These mechanisms lead to clock reactions and travelling reaction fronts, thermal runaway, and flames; to oscillations and excitability; to target patterns, spiral and scroll waves; to bistability, ignition, extinction, and hysteresis; and to complex oscillations and chaos in flow reactors. These phenomena are related to important processes in biology, including the development of cardiac arrhythmias, nerve signal transmission, and animal coat patterning
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Z252093
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Oxford Chemistry Primers No. 19: Atomic Spectra
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This primer provides a systematic and rigorous introduction to the spectra and electronic structure of atoms in the gas phase. Throughout the book, the author explains observed spectra in terms of underlying quantum mechanical principles while at the same time illustrating experimental aspects and chemical applications. The book begins with a review of elementary quantum mechanics as applied to spherically symmetric problems and a discussion of electromagnetic radiation properties. It goes on to detail the spectra of hydrogenic atoms, the alkali metals, the helium atoms, and many-electron atoms at all stages. Topics such as spin-orbit coupling, the Zeeman effect, spin-correlation and the Pauli Principle, Russel-Saunders, and jj-coupling are included. Modern applications and techniques such as lasers and cooling of atoms are briefly discussed. Many topics are covered at two levels in separate sections, so that a newcomer can gain qualitative understanding by omitting some sections and then return later for a more detailed quantitative picture
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Z233935
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Oxford Chemistry Primers No. 2, Aromatic Heterocyclic Chemistry
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Focuses on synthetic aspects, rather than properties, and it covers the essential details and basic principles with reference to all the important classes of heterocyclic compounds. Instructional problems are included as an aid to comprehension, and references to more detailed texts are provided.
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Z252107
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Oxford Chemistry Primers No. 20: Chemical Aspects of Biosynthesis
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This introductory text describes and explains the chemistry involved in the biosynthesis of secondary metabolites. The book emphasizes the pharmacological and toxicological significance of the compounds, and the final chapter reviews their ecological role. Suggestions for further reading are provided
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Z252115
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Oxford Chemistry Primers No. 21: Modern Liquid Phase Kinetics
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The world is not at equilibrium, and the events that give vitality and movement are transitions towards equilibrium from the present state of imbalance. This text examines the chemical transformations that often contribute fundamentally to this process. The book begins with a basic introduction to the kinetics of simple and complex reaction systems in solution. It goes on to present a treatment of the more advanced topics such as solvent effects, fast reaction techniques, and heterogeneous liquid-liquid two-phase systems. An overview of currently active and important research areas in solution kinetics concludes the text. Industrial chemists and students will welcome this superb introduction to a challenging and important topic.
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Z252654
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Oxford Chemistry Primers No. 22: Fractals in Chemistry
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The patterns of frost on a cold window, eroded landscapes, and particles grown in an aerosol all have forms that are conventionally regarded as irregular, with little or no symmetry. In Fractals in Chemistry, the reader is introduced to the fractal dimension, a concept that allows for a unified description of such diverse and irregular objects, and implies that they all possess heretofore unperceived symmetries. The text explains how the growth of such objects is controlled by similar, simple processes, and how modest experiments bring to life the principles involved. Topics include fractal forms, fractal growth, characterizing fractals, and chemistry in fractal environments. Throughout, the text emphasizes the relevance of fractal concepts to the structure and chemistry of porous solids and to the growth of polymers and colloids in liquid and gaseous phases. Concise and easy-to-read, this book is ideal for students and researchers in chemistry, physics, and materials science
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Z252662
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Oxford Chemistry Primers No. 23: Inorganic Materials Chemistry
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Although the chemistry of solid inorganic materials has become increasingly central to chemistry research, the subject has long been inadequately covered. This inexpensive and well-illustrated primer fills the gap with a comprehensive introduction to the subject. Topics include: transition metal oxides, non-stoichiometry, zeolites, layer compounds chemistry, high temperature superconductors, and fullerides. Syntheses of these compound types are presented as well. The book also details powder x-ray diffraction, the major experimental technique used to study and characterize the chemistry of solid inorganic materials. The basis for the method and associated, relevant crystallography is discussed. The experimental data gleaned from the technique is used to illustrate key topics throughout the primer. This tying together of an experimental method and the chemistry is a much needed approach, reflecting the true need of the chemist and the method by which chemistry is taught
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Z258946
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Oxford Chemistry Primers No. 24: Chemical Instrumentation
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Instrumentation lies behind many of the most interesting aspects of contemporary chemistry. Some techniques - such as NMR - owe their existence to electronic instrumentation; others have been made simpler, more reliable, and more precise. Yet undergraduates reading chemistry often have only the most rudimentary understanding of the way in which electronics and allied disciplines have provided powerful tools that enable creative experimentation to be performed. This text introduces students to the devices used in R&D and provides a basic understanding of how the instrumentation works
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Z258954
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Oxford Chemistry Primers No. 25: Bicoordination Chemistry
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The role of transition metals in various biological systems is of great interest to chemists; the specific properties of these metals often define the biological function of the proteins and systems these metals are found in. This volume introduces readers to a number of topics, including the transport and storage of metals; their functions in dioxygen interactions, electron transfer, and enzyme activity; the therapeutic uses of coordination compounds; and the role that small-molecule models can play in advancing our knowledge of the structure and function of transition metals contained in metallobiosites.
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Z258962
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Oxford Chemistry Primers No. 26: Energy Levels in Atoms and Molecules
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An understanding of energy levels in atoms and molecules is an essential foundation for the study of physical chemistry. This book provides the reader with a clear and accessible introduction to electronic structure and quantitized energy levels. It introduces the general principles and lays the groundwork for the further study of quantum mechanics and spectroscopy.
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Z258970
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Oxford Chemistry Primers No. 27: d-Block Chemistry
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Many students find the array of structural types displayed by d-block metal complexes somewhat bewildering when they encounter them for the first time. In this primer, Mark Winter uses clear text and consistently presented molecular structures to help overcome this problem and to provide a concise text for first courses in transition metal chemistry. His student-friendly approach will make the subject more accessible for many, and the clear progression of chemistry employed lays the foundations for more advanced courses at a later date.
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Z271438
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Oxford Chemistry Primers No. 28: Essentials of Inorganic Chemistry 1
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Beginners in chemistry often find the terminology bewildering, and basic concepts difficult to summarize. This primer provides an alphabetical listing of concepts encountered up to a first year undergraduate inorganic chemistry course. Each entry provides more information than can be found in current chemistry dictionaries, and is written in accessible, student-friendly style. Whether using the primer to cram for exams or for quick explanations of unfamiliar topics, every chemistry student should have a copy at their desks
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Z271446
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Oxford Chemistry Primers No. 29: Computational Chemistry
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The uses of computers in chemistry are many and varied, from the modelling of solid state systems to the design of complex molecules which can be used as drugs. This text provides an introduction to the many methods currently used by practising computational chemists and shows the value of computers in modern chemical research. The authors describe the various computational techniques available and explain how they can be applied to single molecules, to assemblies of molecules, and to molecules undergoing reaction. An introductory chapter outlines the hardware and software available, and looks at some applications and developments. Subsequent chapters cover quantum mechanics, molecular mechanics, statistical mechanics, the modelling of biomolecules, and drug design. While emphasizing the use of computers to model biological systems, the authors explain how the methods can be applied to a wide range of chemical problems
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Z271454
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Oxford Chemistry Primers No. 30: Process Development: Fine Chemicals From Grams to Kilograms
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Process development bridges the gap between the laboratory synthesis of an organic compound and its industrial manufacture on a large scale. This concise and readable text uses real examples and case histories from ICI/Zeneca Pharmaceuticals to show the problems which may be encountered in scaling up chemical synthesis, and the ways these problems may be overcome. It shows how it is possible to synthesize multi-kilogram quantities of a new organic compound which has been made in the laboratory only in the milligram scale. A wide range of aliphatic, aromatic, and heterocyclic compounds is covered. This book will be invaluable both to the research chemist involved in the development phase of novel compounds, and the advanced undergraduate interested in the fine chemicals industry.
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Z271462
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Oxford Chemistry Primers No. 31: Organic Synthesis
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This practical book uses a wide range of examples in a versatile approach to the design of effective syntheses. Retrosynthetic analysis--a method of identifying simple starting materials for a synthesis--is introduced with emphasis on the importance of bond polarity and functional group interconversions. The next section discusses how an effective route to a target molecule containing more than one functional group can be followed, while later chapters review methods for the control of chemo-, regio-, and stereoselectivity, and include a discussion of protecting groups. Finally, four syntheses of pyrrolidine alkaloids are compared using previously described principles.
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Z271470
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Oxford Chemistry Primers No. 32: Nuclear Magnetic Resonance
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Nuclear magnetic resonance spectroscopy is an enormously powerful and versatile physical method for investigating the structure and dynamics of molecules. This text provides a clear, concise introduction to the physical principles of NMR, and the interactions that determine the appearance of NMR spectra. It describes and explains how nuclear spins interact with a magnetic field (the chemical shift) and with each other (spin-spin coupling); how NMR spectra are affected by chemical equilibria (exchange) and molecular motion (relaxation); and concludes with an outline of the workings of some simple one- and two-dimensional Fourier transform NMR experiments. The ways in which NMR may be used to study the structures, motions and reactions of molecules are illustrated and discussed. Only essential mathematics and theory are presented. The emphasis throughout is on understanding the basic principles
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Z277673
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Oxford Chemistry Primers No. 39: Photochemistry
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The fascinating subject of photochemistry is explained in a basic and comprehensive manner in this new primer. Aimed at an undergraduate audience, the text describes the `new′ chemistry that follows the absorption of light, and explains how light has this extraordinary influence on chemical behaviour. Examples of established principles are presented examining the way in which life and the other natural processes depend on photochemistry, and also how photochemistry can be used in a variety of applications.
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Z233951
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Oxford Chemistry Primers No. 4, Aromatic Chemistry
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All the basic principles of the field of aromatic chemistry are clearly presented in this important account. Many compounds of industrial and biological significance are used as examples with consideration given to structure, reactions, and properties. Topics such as thermodynamic versus kinetic control and pericyclic reactions are also introduced. In addition to benzene and the classes of aromatic compounds derived from it, the text covers polycyclic arenes, and the small and large ring systems which are embraced by the wider definition of aromaticity. The text will be especially useful for courses in organic chemistry.
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Z233978
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Oxford Chemistry Primers No. 5, Polar Rearrangements
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The general principles of polar rearrangements are brought together in this text, which deals with all the major rearrangements involving electron-deficient atoms or charged intermediates. Reactions involving migration to electron-deficient carbon, nitrogen, oxygen and sulfur, and sigmatropic rearrangements involving polar species, are thus treated in a coherent and consistent manner. Clear discussions of the reaction mechanisms are followed by examples of synthetic applications providing a concise yet comprehensive account of the nature of and importance of these processes
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Z402230
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Oxford Chemistry Primers No. 50: Heat Transfer
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This primer follows a classical approach to the study of heat transfer with main chapters on conduction, forced convection, natural convection and radiation. Practical problems, however, do not normally divide neatly into purely conduction problems, purely forced convection and so on, although texts often assume this. To overcome this barrier, the author demonstrates in examples and problems that more than one aspect of heat transfer may be needed to solve a single practical problem. The book covers the essential material of a text twice its length, making it easier for the reader to find and understand key principles. It will be of particular interest to undergraduate students in engineering, especially in mechanical and chemical engineering, and to professional engineers working on heat transfer.
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Z513806
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Oxford Chemistry Primers No. 6: Oxidation & Reduction in Organic Synthesis
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The manipulation of functional groups by oxidative or reductive processes is central to organic chemistry. Despite the importance of these reactions, no existing text has attempted to summarize them simply for students. Together with a later volume in the series, this book provides a clear and comprehensive summary of oxidative and reductive processes, emphasizing general principles and common factors, and showing the applications of these compounds in organic synthesis.
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Z238953
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Oxford Chemistry Primers No. 8: Reactive Intermediates
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Neutral reactive intermediates -- radicals, carbenes, nitrenes, and aryenes -- occupy a fascinating place in the history of organic chemistry. First regarded as mere curiosities, neutral reactive intermediates ultimately came under the intense scrutiny of physical organic chemists from a mechanistic point-of-view. This concise text concentrates on how these electron-deficient species now play a key role in synthetic chemistry research. Important reactions are clearly and simply laid out with carefully chosen examples that illustrate their use in organic synthesis. Each chapter includes problems as well as suggestions for further reading. Undergraduates will find Reactive Intermediates an invaluable summary of this important topic in organic chemistry--one that fills a gap created by the superficial treatment accorded these valuable compounds in most chemistry textbooks.
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Z238961
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Oxford Chemistry Primers No. 9: Foundations of Organic Chemistry
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Advanced high-school and beginning undergraduate students will find this book a readable and stimulating summary of the fundamentals of organic chemistry. The first three chapters introduce basic physical chemistry and lay the groundwork for the mechanistic organic chemistry covered later in the book. The importance of bonding and mechanisms are stressed throughout, and students are encouraged to apply their chemical knowledge in new and unfamiliar situations in order to develop and sustain their interest. The wide range of examples includes natural products and pharmaceuticals, with the final chapter exploring some new developments and providing an introduction to current research.
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Z288608
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Oxidations in organic chemistry
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A complete source of information on oxidations of organic compounds, with emphasis on preparative aspects and results. Important features include: discussions on oxidizing agents and on oxidation reactions using them; correlation tables showing what oxidizing agents are suitable for conversions of particular compounds to their oxidation products; and a collection of typical laboratory procedures for the main types of oxidations. All information is supported by examples, thorough referencing, and indexing.
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Z730203
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Palladium in Heterocyclic Chemistry: A Guide for the Synthetic Chemist, 2nd ed. the method of choice for the synthesis of a wide range of biaryls and heterobiaryls
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Heterocycles are of paramount importance in the pharmaceutical industry and palladium chemistry is one of the most novel and efficient ways of making heterocycles. Today, palladium-catalyzed coupling is the method of choice for the synthesis of a wide range of biaryls and heterobiaryls. The number of applications of palladium chemistry to the syntheses of heterocycles has grown exponentially.
These developments highlight the need for a monograph dedicated solely to the palladium chemistry in heterocycles and this book provides a comprehensive explanation of the subject. The principal aim of the book is to highlight important palladium-mediated reactions of heterocycles with emphasis on the unique characteristics of individual heterocycles. This book comprises a compilation of important preparations of heteroaryl halides, boranes and stannanes for each heterocycle.
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Z272280
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Phase-Transfer Catalysis: Fundamentals, Applications, and Industrial Perspectives
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This book is the definitive reference on phase-transfer catalysis (PTC). This first practical guide to performing PTC in industry, includes key information and analyses found in no other publication. The book provides a thorough introduction to the fundamentals of PTC as a synthetic organic chemistry technique, including reaction mechanisms, selectivity, rates and kinetics. It gives specific guidelines on how to optimize catalyst, solvent, base, hydration, and more, based on reaction characteristics. The section on applications includes nucleophilic displacement reactions, oxidation and reduction reactions, and such special topics as insoluble PTC (triphase catalysis), polymerization, chiral catalysis, applications in environmental and analytical chemistry, and transition metal co-catalyzed PTC. Throughout the book, PTC applications in key industries are discussed--including organic chemicals, polymers, pharmaceuticals, agrichemicals, monomers, petrochemicals, flavors and fragrances, additives, dyes, and specialty chemicals.
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Z258792
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Physical Organic Chemistry, 2nd ed.
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Covers the underlying principles of reaction pathways, physical forces, and techniques for mechanistic investigations.
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Z287768
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Preparative Carbohydrate Chemistry
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Offers relevant chapters on reactions and derivative forms of carbohydrates, including commonly used methods as well as new experimental procedures. Also contains insightful chapter commentaries and succinct topic histories.
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Z249491
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Protocols For Oligonucleotide Conjugates: Synthesis and Analytical Techniques
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Leading researchers provide the latest protocols for synthesizing oligonucleotide conjugates and explain the latest techniques for analyzing them. These techniques are widely used by pharmaceutical companies as part of the permit process for new drugs. They are also useful to molecular biologists and antisense researchers. Each protocol includes an introduction, a list of materials (including suppliers), step-by-step instructions, and notes for avoiding pitfalls and achieving the best results
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Z405418
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Radicals, Ion Radicals, and Triplets: The Spin-Bearing Intermediates of Organic Chemistry
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This overview of all major types of spin-bearing radicals was written by an internationally acknowledged expert in the field with over two decades′ research experience with radicals--important intermediates in organic reactions. While many new synthetic methods involving radicals have been developed and discussed in the past five years, this is the only book focusing on the physical-organic aspects of radical chemistry.
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Z251976
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Reflections On Symmetry In Chemistry And Elsewhere
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Z703354
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Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design F. Dorwald, John Wiley & Sons, 2005, 389 pp., soft cover
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Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds.
This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia.
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Z514799
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Stereochemistry
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Stereochemistry is defined as the study of the three-dimensional structure of molecules. Stereochemical considerations are important in both isomerism and studies of the mechanisms of chemical reactions. Implicit in a mechanism is the stereochemistry of the reaction: in other words, the relative three-dimensional orientation of the reacting particles at any time in the reaction. Concentrating on organic chemistry, early chapters deal mainly with definitions of terms such as chirality, enantiomers, diastereoisomers and racemisation, complete with suitable examples to illustrate key concepts. Use of a polarimeter and associated definitions are described, together with two different conventions d, l and R, S for specification of configuration. Chirality without a stereogenic center, in molecules such as allenes for example, is also covered. The distinction between conformation and configuration is developed to include assignment of configurations to di-substituted cyclohexanes and to the decalins. The conventions E, Z and Re, Si are introduced for sp2 hybridised carbons as found in alkenes and carbonyl compounds. Diastereotopic groups are discussed. Aspects of stereochemistry are explored through consideration of addition reactions to alkenes and carbonyl groups, nucleophilic substitution, and reactions (and interactions) involved in the resolution of racemic mixtures.
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Z247952
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Stereochemistry Of Organic Compounds
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Long awaited by the chemistry community, here is the most important work on stereochemistry--the study of molecules in 3D--by the leading authorities in the field. It is the first comprehensive review of this important field in 30 years, since Eliel′s original groundbreaking work, Stereochemistry of Carbon Compounds, was published. The book provides a thorough, organized treatment of modern stereochemistry as applied to organic compounds, covering both basic principles and practical aspects. Includes over 1,000 illustrations and chemical structures, numerous tables including ones on conformational energies and physical properties, over 2,500 references, and a glosssary of terms.
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Z261750
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Stereoselective Synthesis
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Introduces a new, simplified classification for stereoselective reactions based on changes in the number of chiral centres taking place, emphasizing the three-dimensional representations of transition states in which stereoselectivity is determined. Using stereochemical vocabulary in accordance with IUPAC rules, it covers analysis of factors in which asymmetric induction occurs, the interplay between steric and electronic effects, the importance of conformational control, advantages of intramolecularity and the majority of important reaction types used in modern stereoselective synthesis.
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Z251917
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Tactics Of Organic Synthesis
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This reference emphasizes the tactical considerations needed to optimize synthetic results in the laboratory--an area most books neglect. Bringing together information that currently lies scattered throughout the literature, it approaches synthesis from a modern point of view. Ho presents both the general aspects of molecular assembly and important new reactions and reaction combinations. Includes over 500 flowcharts and illustrations that clearly demonstrate the subjects discussed.
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Z273147
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Theoretical & Physical Principles Of Organic Reactivity
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This book covers the important topic of organic reactivity - how and why molecules react with each other - presenting both theory and applications. Places particular emphasis on valence bond theory.
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Z287458
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Total Synthesis Of Natural Products Volume 10 Acyclic and Monocyclic Sesquiterpenes, Part A
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This is the latest volume in a series on the reported total syntheses of various groups to natural products, with commentary on the strategy involved and with emphasis on any stereochemical control. Volume Ten focuses on acyclic and monocyclic compounds and sheds light on the structure and makeup of this important class of hydrocarbons. A useful and practical tool for researchers interested in locating any of the major classes of sesquiterpene compounds, the author will also provide, if needed, a database to the more than 1,600 articles on sesquiterpene synthesis. The ultimate index to the newest experimental work in synthetic chemistry, this latest volume in The Total Synthesis of Natural Products series is also a glossary to the new language of chemistry in the next century.
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Z233757
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Total Synthesis Of Natural Products Volume 9
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Offers the first definitive reference for total synthetic approaches to a wide variety of natural products. The authors of the individual chapters are experts in their respective fields and each of them has produced an up-to-date description of the state-of-the-art of total synthesis in their area.
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Z421804
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Transition Metals in the Synthesis of Complex Organic Molecules, 2nd ed.
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Written for organic chemists, this all-new second edition offers an easy entry into the field of organotransition metal chemistry without requiring a background in inorganic chemistry. The book first covers the basics of transition metal chemistry and gives a practical introduction to the mechanisms by which organometallic reactions occur. The organic chemistry of transition metals is then presented by class of metal complex, with many examples of applications in the synthesis of natural products, pharmaceuticals, polymers, and materials. Ideal for advanced undergraduate and graduate students as well as all practicing synthetic organic chemists.
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Z203947
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Vogel’s Textbook of Practical Organic Chemistry, 5th Ed. A. Vogel, et al., ed., Prentice Hall, 1996, 1552 pp., hard cover
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This edition retains the comprehensive, reference-text character, updated, with the introduction of new reagents and techniques as well as the development of a philosophy of organic synthesis, integrating mechanistic theory with the strategy and methodology of synthesis. Chapters deal with experimental techniques, and spectroscopic methods, as well as specific aliphatic, aromatic, alicyclic, heterocyclic, and organic compounds.
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