Long-established as the gold standard in the field, this sixth edition equips one with an unsurpassed treatment of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline. This classic book includes a full discussion of toxicokinetics; how each body system responds to poisons; and the specific effects of a wide range of toxic agents pesticides to radiation. It covers recent advances in molecular biology, pharmacogenetics, clinical toxicology, and behavioral/clinical research.
An updated collection of detailed procedures used to degrade and dispose of a broad range of hazardous chemicals whether in bulk quantities, solutions in various solvents or spills. This edition features new chapters on the removal of metal ions and biological stains from solution; the degradation of mycotoxins, enzyme inhibitors, polycyclic heterocyclic hydrocarbons and highly reactive reagents such as butyllithium, peracids and phosgene as well as the use of much less hazardous reagents including molecular sieves. A list of hazardous compounds indexed by name, molecular formula and CAS Registry Number offers ready access to the data.
A valuable reference tool for those seeking detailed information and guidance on specific safety and health issues, Handbook of Laboratory Health and Safety, Second Edition is also much more. By providing a set of clear, easy-to-follow guidelines that serve as a rational framework for creating site-specific health and safety requirements, it, in effect, arms laboratory managers with a solid foundation upon which to build—or reengineer—a comprehensive program for identifying, managing, and controlling health and safety hazards in the laboratory. All of the authors′ recommended guidelines are clearly presented in the section entitled "Suggested Laboratory Health and Safety Guidelines." Each chapter of the handbook refers to the relevant sections of the Suggested Guidelines, explains the basis for the recommendations, and provides guidance on how to comply. Offering a feasible, easily implemented approach to designing and maintaining a safe workplace, Handbook of Laboratory Health and Safety is an indispensable tool for all those responsible for safeguarding the health and safety of lab workers and the residents of the ambient community
This volume updates and combines two National Academy Press bestsellers--Prudent Practices for Handling Hazardous Chemicals in Laboratories and Prudent Practices for Disposal of Chemicals from Laboratories--which have served for more than a decade as leading sources of chemical safety guidelines for the laboratory. Developed by experts from academia and industry, with specialties in such areas as chemical sciences, pollution prevention, and laboratory safety, Prudent Practices for Safety in Laboratories provides step-by-step planning procedures for handling, storage, and disposal of chemicals. The volume explores the current culture of laboratory safety and provides an updated guide to federal regulations. Organized around a recommended workflow protocol for experiments, the book offers prudent practices designed to promote safety and it includes practical information on assessing hazards, managing chemicals, disposing of wastes, and more. Prudent Practices for Safety in Laboratories is essential reading for people working with laboratory chemicals: research chemists, technicians, safety officers, chemistry educators, and students.
This is a slim, benchtop reference collection of tips and warnings on the safe handling of chemicals and biologicals, listed alphabetically by compound. Extracted from a wide range of Cold Spring Harbor Laboratory Press manuals, this valuable information is presented in a handy format designed for easy use. The volume also includes helpful charts and tables.
Since the 1950′s, this book has been the number one resource for those who need to evaluate the hazard of substances used in commerce. The eleventh edition contains extensive data on approximately 26,000 substances, including 2000 new entries. The three-volume set includes Immediately Dangerous Life or Health (IDHL) levels for approximately 1000 chemicals, proving essential for designing adequate ventilation systems and selection of respiratory protection. Other highlights include: A special appendix containing information of nerve gases and biological agents that might appear in the workplace as a result of terrorist activity; the only reference that combines, for so many substances, data on toxicological, fire, reactivity, explosive potential, and regulatory information; Regulatory data covers exposure level classifications for a number of regulatory agencies, from OSHA to the U.S. Department of Transportation.
Different from other books, this unique volume presents basic toxicology principles and applications in a sophisticated yet nontechnical style. It provides an understanding of both the strengths and limitations of the discipline of toxicology and its benefits. This primer is valuable for virtually any non-toxicologist.