 | Z703761 | G Protein Coupled Receptor-Protein Interactions | This exciting volume elucidates how GPCRs organize signal transduction and control intracellular activities. Chapters written by the recognized expert in each respective topic offer state-of-the-art updates on the principles and technology, as well as stepwise protocols for methods currently applied to the analysis of protein-receptor interactions
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 | Z704148 | G Protein Coupled Receptors Handbook | Authors describe the knowledge of GPCR receptor structure and function, the different mechanisms involved in the regulation of GPCR function, and the role of pharmacological chaperones in GPCR folding and maturation. They also present new findings about how GPCR dimerization/ oligomerization modifies the properties of individual receptors and show how recent developments are leading to significant advances in drug discovery, such as the detection of ligands for orphan GPCRs. Also discussed are the most recent developments that could lead to new drug discoveries: role of GPCRs in mediating pain, development of receptor-type selective drugs based on the structural plasticity of receptor activation, and identification of natural ligands of orphan GPCRs (deorphanization) as possible drug targets.
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 | M5565 | G Protein Pathways Part B, G Proteins and their Regulators, Methods in Enzymology Vol 344 | This volume covers topics such as the structure and identification of functional domains of G proteins, and activation of G proteins by receptors or other regulators. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modelling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume.
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 | M5440 | G Protein Pathways, Part A Receptors, Methods in Enzymology Vol 343 | G Protein Pathways is the first of three volumes examining the nature of heterotrimeric G proteins. The text takes an integrated approach to studying common experimental questions at many different levels related to G proteins. Methods related to G proteins using molecular modeling, systems biology, protein engineering, protein biochemistry, cell biology, and physiology are all accessible in the same volume.
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 | Z701416 | G Protein Signaling: Methods and Protocols | The involvement of G protein coupled systems in a range of biological processes in organisms from yeast to man has generated a large degree of interest. Due to the interdisciplinary nature of G protein coupled systems the types of techniques used to study their functions varies considerably. The methods contained in this text contain complementary biochemical, molecular biological and cell biological approaches to addressing questions so that they can be studied from multiple perspectives and adopted by different types of laboratories. These methods are of interest to scientists studying physiological roles of G protein systems, the signal transduction systems associated with these G proteins systems as well as the molecular nature of G proteins themselves.
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 | G1540 | G Protein-Coupled Receptors | Covering recently developed methods in membrane-bound receptors, this book emphasizes receptor structure and function, knowledge of which is essential to the study of signal transduction. G Protein-Coupled Receptors has utilized contributors from domestic and international sources, providing a broad base of knowledge. Some topics covered are the regulation of receptors; phosphorylation of G-protein-coupled receptors and ion channel receptors; desensitization studies using electrophysiological or confocal microscopic methods and the search for endogenous ligands for orphan receptors.
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 | G2415 | G Proteins: Techniques of Analysis | This book covers essential methods - with a commitment to those techniques of proven and current utility. This title includes expression and functional analysis of G proteins; evaluation of covalent modifications and other regulatory phenomena; and, mapping pathways established among receptors, G proteins, and effectors. Includes contributors from key institutions. Each author offers clear instructions to establish a synthesized, concise and consistent approach to each chapter, beneficial to all.
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 | G3543 | GTPase Protocols: The Ras Superfamily | This is a collection of techniques to probe the function of these ubiquitous proteins both in vitro and in vivo. Each technique includes step-by-step instructions, tips on avoiding pitfalls and troubleshooting, and ancillary notes explaining how to adapt each procedure in the event of problems. The methods cover the spectrum of core techniques required for the five major GTPase subfamilies (Ras, Rho, Rab, Arf, and Ran) and permit a diversity of applications ranging from structural studies on a GTPase to real time in vivo analysis. This book illuminates the techniques used to study this family of proteins.
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 | G9403 | GTPases | GTPases are proteins that act as molecular switches to control biochemical pathways within a cell. This book provides a complete guide to the properties and cellular roles of all the major families of GTPases, including the heterotrimeric G proteins and the small GTPases Ras, Rho, Rab, Arf and Ran. These proteins have caught the attention of those studying control of proliferation, differentiation, cell polarity, cell movement and vesicle and protein trafficking.
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 | Z412546 | Gardner’s chemical Synonyms and Trade Names, 11th ed. | This essential reference contains some 35,000 entries, many of which have been added for the first time. Features a comprehensive selection of chemicals including bulk inorganic chemicals, major pesticides, dyestuffs, surfactants, metals, and alloys. Entries, whenever possible, contain detailed information on definitions, classifications, chemical composition, functions, applications, and suppliers. A feature new to this Edition is the inclusion of physical properties data for pure chemicals. Data that has been provided, as available, include the melting point, boiling point, density or specific gravity, refractive index, optical rotation, ultraviolet absorption, solubility, and acute toxicity.
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 | Z528188 | Gas Chromatography Simulation & Optimization Software | Use GC-SOS to develop high efficiency capillary gas chromatography methods on your PC. This easy-to-use program provides an efficient and effective way to develop fully optimized GC methods. Off-line simulations can be rapidly and accurately performed to determine the effects of varying temperature, pressure, and/or column size conditions on your separations. Faster method development along with substantially improved separations can result in considerable cost savings along with increased run performance. Also serves as an invaluable tool for learning GC retention principles.
•Enter run conditions and retention data from actual data
•Import your chromatogram directly into GC-SOS
•Auto-Optimization feature finds an optimized set of run conditions for your separation
•Detailed printouts serve as a convenient method documentation tool
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 | Z271756 | Gas Chromatography, 2nd ed. | This book presents an introduction to gas chromatography, including examples of applications. Shows readers malfunctions that can occur enabling them to recognize and fix faults.
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 | Z651974 | Gastrulation: From Cells to Embryo | Gastrulation is the complex process of cell differentiation, following the division of a fertilised embryo, during which tissue layers are formed and the overall body plan is established. This book is the definitive guide to this vitally important period in embryonic development, providing authoritative and up to date information that includes the first comprehensive interspecies comparison, cell movements and patterning events, the roles of individual genes and gene families, and the evolution of gastrulation.
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 | G4647 | Gel Electrophoresis of Proteins: A Practical Approach, 3rd ed. | | pricing |
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| | Z357413 | Gel Electrophoresis: Essential Data Series | This volume presents comprehensive data on gel electrophoresis of proteins, nucleic acids, nucleoproteins and carbohydrates. Also presented are sections on electrophoresis chemicals, types of apparatus, troubleshooting, and manufacturers and suppliers.
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 | Z730351 | Gene Cloning: Principles and Applications | The ability to successfully clone genes underlies the majority of our knowledge in molecular and cellular biology. Existing textbooks describe what has been learnt from cloned genes but include little detail on how the cloning was achieved and how the techniques involved are carried out in the laboratory. Gene Cloning introduces the diverse array of techniques available to clone genes and how they can be used effectively both in the research laboratory, to gain knowledge about the gene, and for use in biotechnology, medicine, the pharmaceutical industry, and agriculture. It shows how cloning genes is an integral part of genomics and underlines its relevance in the post-genomic age, as a tool required to test predictions experimentally.
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| | G2777 | Gene Construction Kit Brochure | Allows graphic manipulation of DNA Sequences and sophisticated plasmid drawing options. It has an award winning interface design that allows graphic manipulation of DNA sequences in addition to providing sophisticated drawing capabilities. GCK was named the "Best Plasmid Mapping Software" by the Biotechnology Software.
• Ideal for planning and tracking complex construction projects
• Manipulate actual DNA sequences through a unique and innovative graphical interface
• View construct either as a text sequence or graphically, linear or circular
• Automatically monitor and adjust DNA fragment ends during cutting and pasting
• Define thickness, pattern, shape, direction, and color for each DNA segment
• Search, download and import GenBank and EMBL files with all GenBank feature table items translated automatically into GCK features.
• Unique Chronography feature tracks the history of any given DNA segment and maintains alternative views
• Cut and paste DNA fragments from one construct to another (including segment history)
• View predicted electrophoresis patterns of restriction digests including partial digests
• Show DNA with protein sequence and/or with restriction enzyme or other sites of interest
• Create illustrations containing multiple constructs, gels, sequence listings, free text, legends and other graphics
• Create silent mutations to add or remove a restriction site from a sequence without changing the coding information
• Mark restriction sites using one or more completely editable and expandable enzyme lists
• Find Open Reading Frames using any codon table you specify
• Display the name of any region within the construct window
• Frame segments of DNA in the sequence display. Frames can encompass the site markers, sequence, and/or regions of a construct.
• Display and manipulate multiple constructs in the same illustration window
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| | G0667 | Gene Construction Kit For Windows | Allows graphic manipulation of DNA Sequences and sophisticated plasmid drawing options. It has an award winning interface design that allows graphic manipulation of DNA sequences in addition to providing sophisticated drawing capabilities. GCK was named the "Best Plasmid Mapping Software" by the Biotechnology Software.
• Ideal for planning and tracking complex construction projects
• Manipulate actual DNA sequences through a unique and innovative graphical interface
• View construct either as a text sequence or graphically, linear or circular
• Automatically monitor and adjust DNA fragment ends during cutting and pasting
• Define thickness, pattern, shape, direction, and color for each DNA segment
• Search, download and import GenBank and EMBL files with all GenBank feature table items translated automatically into GCK features.
• Unique Chronography feature tracks the history of any given DNA segment and maintains alternative views
• Cut and paste DNA fragments from one construct to another (including segment history)
• View predicted electrophoresis patterns of restriction digests including partial digests
• Show DNA with protein sequence and/or with restriction enzyme or other sites of interest
• Create illustrations containing multiple constructs, gels, sequence listings, free text, legends and other graphics
• Create silent mutations to add or remove a restriction site from a sequence without changing the coding information
• Mark restriction sites using one or more completely editable and expandable enzyme lists
• Find Open Reading Frames using any codon table you specify
• Display the name of any region within the construct window
• Frame segments of DNA in the sequence display. Frames can encompass the site markers, sequence, and/or regions of a construct.
• Display and manipulate multiple constructs in the same illustration window
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 | Z702358 | Gene Expression Profiling: Methods and Protocols | Leading scientists in gene expression methodology and bioinformatics data analysis describe readily reproducible methods for measuring RNA levels in cells and tissues. The techniques presented include new methods for applying the Affymetrix GeneChip, SAR-SAGE, StaRT-PCR, SSH, the Invader Assay, and ADGEM. The authors also provide critical bioinformatics insight and resources for data analysis and management. By distilling the basic underlying principles of many methods to a few straightforward concepts, investigators can easily choose the method most appropriate to their application
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 | Z373974 | Gene Isolation and Mapping Protocols: Methods in Molecular Biology, Vol. 68 | A collection of the most up-to-date techniques for gene isolation and mapping, including the latest methods for gene characterization using data base analyses. Also, numerous time-saving techniques and informative explanations about certain steps are included.
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 | G5916 | Gene Knockout Protocols | Highly skilled investigators in gene targeting and mouse genetics describe their best techniques for the design of targeting constructs and for the analysis of the mouse phenotype. These include embryo transplantation, in vitro embryonic stem cell differentiation, creation of aggregation chimeras, mouse pathology, embryo cryopreservation, and transplantation. State-of-the-art and highly practical, it constitutes an invaluable source of readily reproducible techniques for genetic researchers today.
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 | Z730165 | Gene Mapping, Discovery, and Expression: Method and Protocols | A collection of cutting-edge computational tools and experimental techniques to study how genes are regulated, and to reconstruct the regulatory networks through which various cell-types are produced. On the computational side, web-based technologies to localize genes, to access and retrieve data from microarray databases, to conduct comparative genomics, and to discover the potential “codes” in genomic DNA that may control the expression of protein-coding genes. Detailed experimental techniques described include methods for studying chromatin structure and allele-specific gene expression, methods for high-throughput analysis to characterize the transcription factor binding elements, and methods for isolating and identifying proteins that interact with DNA.
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| | Z306177 | Gene Probes 1 | Over 85 key protocols for the synthesis, labeling, detection, and quantification of DNA, RNA, oligodeoxynucleotide, and antibody probes are provided. It brings together key practical advice and step-by-step protocols for all of the major methods of probe labeling and detection.
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 | Z306185 | Gene Probes 2 | Over 100 protocols for using DNA, RNA, oligodeoxynucleotide, and antibody probes in screening gene libraries, mapping, gene structure determination, analysis of gene expression, and mutational studies, are presented.
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 | G1793 | Gene Probes: Principles and Protocols | Volume 179 of the Methods in Molecular Biology series contains an outstanding collection of time-tested protocols for designing and using genes probes in wide variety of applications. The applications covered range from searching for specific genes in the human chromosome to the detection of microorganisms and their toxins in the environment and in food samples, as well as in the diagnosis of human disease. Helpful tutorials explain the principles of gene probe design, labeling, detection, target formation, and hybridization conditions
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 | Z730327 | Gene Regulation 5th ed. | Gene regulation is an essential process in the development and maintenance of a healthy body. This Fifth Edition provides a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview. For this edition, in addition to updating of existing material, sections on important methodologies have been expanded, and a new section included on regulation by small interfering RNAs. More detail has been added on the role of multi-protein complexes in transcriptional activation, and to the discussion of the regulation of transcription factor activity by specific modifications, to include acetylation and ubiquitination, as well as phosphorylation. The final chapter on gene regulation and human disease now includes additional novel examples, and a new section on the therapeutic potential of gene regulation.
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 | Z340790 | Gene Targeting: A Practical Approach, 2nd Edition | This updated version includes the major new techniques and tried-and-tested practical protocols. It concentrates on gene targeting in mouse ES cells, but the techniques can be adapted to applications in tissue culture, including human cells.
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 | G9291 | Gene Therapy: Therapeutic Mechanisms and Strategies | This reference covers all aspects of gene therapy, including viral and nonviral delivery systems, targeted diseases, regulatory issues, and FDA requirements. It investigates genetic bullets to block HIV-1 replication and genetic guns to deliver antiviral agents. It examines donor cells, vector systems, and functional genes; defines extra- and intracellular pathways and barriers for gene delivery; addresses the interaction of micelles and liposomes with nucleic acids; describes the formulations, pharmacology, and toxicology of oligonucleotides; considers RNA catalysis and decoy RNAs; and outlines hematopoietic stem cell procurement.
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 | G8416 | Gene Transfer Methods: Introducing DNA Into Living Cells and Organisms | A critical aspect of the molecular revolution is that DNA frequently must be re-introduced into living cells to determine activity. The goal of this book is to compile a core set of numerous DNA transfer methods within a single volume. Chapters discuss DNA transfer into cells of bacterial, fungal, and mammalian origin, as well as into the germlines of flies, mice, and plants. Each chapter includes supplementary information such as common problems and specific troubleshooting suggestions. Progress and hurdles in the field of human gene therapy are presented.
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 | Z703729 | Gene Transfer to Animal Cells | Gene transfer to animal cells was first achieved more than 30 years ago. Since then, transformation technology has developed rapidly, resulting in a multitude of techniques for cell transformation and the creation of transgenic animals. As with any expanding technology, it becomes difficult to keep track of all the developments and to find a concise and comprehensive source of information that explains all the underlying principles. This book describes the principles behind gene transfer technologies, how gene expression is controlled in animal cells and how advanced strategies can be used to add, exchange or delete sequences from animal genomes in a conditional manner. The final chapter provides an overview of all the applications of animal cell transformation.
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 | Z730033 | Gene Transfer: Delivery and Expression of DNA and RNA, A Laboratory Manual | Understanding gene function and regulation requires rigorous testing in live cells and organisms. Recent advances have provided a variety of new strategies for delivering DNA and RNA into cells and probing their expression, as well as new clinical applications that rely upon the introduction of genetic material. The vast number of available techniques for clinical and laboratory research often makes selecting the optimal method a difficult process. This book provides the first comprehensive guide to technical approaches for delivering nucleic acids into cells and organisms and of ensuring (even manipulating) appropriate expression. The detailed, step-by-step protocols include viral and nonviral methods of gene delivery, transgenic approaches, strategies for the regulation of transgene expression, and modification of the host response.
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 | Z702617 | Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, 2nd ed. | This edition offers current data on delivery systems and therapeutic strategies, gene expression and detection, and disease targets and therapeutic strategies. It presents results and prospects in gene therapy clinical trials, other cell-based therapies and trials, and regulatory issues. Topics include optimization of non-viral gene therapeutics, gene therapy for cancer, and DNA vaccines.
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| | P5980 | Gene cloning and analysis by RT-PCR | This new laboratory protocols manual provides investigators with up-to-date RT-PCR based methods for gene cloning and analysis. Since RT-PCR was first described for the detection of low-abundance mRNAs, the method has been extended to quantitative measurements of relative and absolute levels of single and multiple mRNAs. Methods for obtaining RNA for RT-PCR have also been extended to include analysis of mRNA levels in clinical samples and even in single cells.
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 | Z700991 | Generation of cDNA Libraries:Methods and Protocols | Expert researchers and inventors in the field describe their own proven techniques for generating cDNA/mRNA libraries to identify the functions of specific decoded gene sequences. A wide variety of techniques is presented for enhancing the generation of complete and full-length libraries, and for confirming the quality of the cDNAs generated. Among the applications detailed are electrophoresis, Northern blotting, single cell microarray analysis, subtractive hybridization, subtractive cloning, gene cloning, and peptide library generation. Each method includes background information, step-by-step instructions, a list of reagents, operational tips, and notes on instrumentation.
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 | Z702420 | Genes VIII | Two decades ago Benjamin Lewin's Genes revolutionized the teaching of molecular biology and molecular genetics by introducing a unified approach to bacteria and higher organisms. Genes has remained at the cutting edge of molecular biology, covering gene structure, organization, and expression. Originally the text opened with the genetic code and worked toward genome structure. Genes VIII changed the approach to begin with the sequence of the human and other genomes and starts with complete coverage of recent advances in genomics. The coverage of genomics is then integrated throughout the text.
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 | G6292 | Genes and Signals: Imposing Specificity on Enzymes by Recruitment | Many cellular functions require the orderly switching on and off of gene transcription, often in response to signals from other cells or the environment. This concise, attractively illustrated volume is a textbook on gene regulation and its importance in development and evolution. But the book also argues that understanding how transcription-related enzymes are controlled will reveal much about the regulation of enzymes in other biological processes as well.
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| | Z369500 | Genetic Analysis of Pathogenic Bacteria: A Laboratory Manual | Five years' progressive refinement in the Cold Spring Harbor course in Advanced Bacterial genetics has produced a manual that teaches theoretical and practical molecular genetic approaches to bacterial pathogenicity. Chapters on concepts, technologies and applications are followed by 15 multifaceted experiments.
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 | Z700177 | Genetic Library Construction and Screening | This volume is designed to provide an easily accessible introduction to core strategies in the application of modern recombinant DNA technology. The first chapters directly address the applications of polymerase chain reaction to a variety of problems in DNA cloning that are, or have been, extremely challenging using more traditional approaches and technologies. These include cDNA cloning and transcript mapping, mutagenesis as well as the cloning of very long transcripts and protocols using limiting amounts of total RNA. Further chapters describe approaches to subtractive cloning technologies and specialized expression cloning and library screening strategies.
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 | Z703516 | Genetic Variance Detection: Nuts & Bolts of DHPLC in Genomics | Studies of sequence variation are an integral part of genome research, because of differences in the genomic sequences between individuals. Variations in mammalian genomic sequences occur at an estimated frequency of at least one base per thousand bases. In the case of the human genome, this totals more than three million variances. These variances are typically present in the form of single nucleotide polymorphisms (SNPs). The relationship between the variability in the sequence of specific genes among individuals to their susceptibility to disease is the key to understanding gene function. This book focuses on a technology used for screening of unknown sequence variants, namely denaturing high-performance liquid chromatography (DHPLC).
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| | Z730947 | Genetic Variation: A Laboratory Manual Hardback | This manual is the first compendium of protocols specifically geared towards genetic variation studies, and includes thorough discussions on their applications for human and model organism studies. It covers the complete spectrum of genetic variation-from SNPs and microsatellites to more complex DNA alterations, including copy number variation. The early sections of the manual are devoted to study design and generating genotype data, the use of resources such as HapMap and dbSNP, as well as experimental, statistical, and bioinformatic approaches for analyzing the data. The final sections include descriptions of genetic variation in model organisms and discussions of recent insights into human genetic ancestry, forensics, and human variation.
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 | Z704601 | Genetics for Dummies | Reveals the connections between genetics and specific diseases. Understand the science and the ethics behind genetics. Want to know more about genetics? This non-intimidating guide gets you up to speed on all the fundamentals. From dominant and recessive inherited traits to the DNA double-helix, you get clear explanations in easy-to-understand terms. Plus, you'll see how people are applying genetic science to fight disease, develop new products, solve crimes, and even clone cats. Discover: What geneticists do; How traits are passed on; How genetic counseling works; The basics of cloning; The role of DNA in forensics; The scoop on the Human Genome Project
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 | G7416 | Genetics: Analysis of Genes and Genomes | Genetics: Analysis of Genes and Genomes represents the most current, comprehensive, and progressive introduction to genetics and genomics. Keeping pace with the latest developments in genetics, the authors treat classical, molecular, and population genetics as distinct but unified subjects that illuminate and reinforce each other throughout the text. This integrated approach to teaching genetics is a logical progression in an era when the various subdisciplines of genetics are so closely interwoven.
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 | Z378410 | Genome Analysis: Laboratory Manual Series Volume 1: Analyzing DNA | This volume presents exhaustive coverage of techniques for: purifying genomic DNA; manipulating high-molecular weight DNA; several specialized DNA sequencing methods; and computational analysis of DNA and protein sequences. Appendices include recipes for common reagents, basic procedures, safety, and a compilation of ″useful facts.″
Assuming only a basic knowledge of molecular biology, these manuals explain how to clone, manipulate, analyze, and sequence large segments of DNA, and relate sequence to phenotype variation. Techniques, written for human as well as other animal genomes, deal plainly with sources of failure and how to avoid them. Protocols are written by experts, often by those who created the methods. The series is an excellent complement to the bible of recombinant DNA, Molecular Cloning.
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 | Z382663 | Genome Analysis: Laboratory Manual Series Volume 2: Detecting Genes | Topics include Strategies for gene discovery in mammalian systems; Constructing and screening normalized cDNA libraries; Direct cDNA selection; Exon trapping; and Detection of DNA variation
Assuming only a basic knowledge of molecular biology, these manuals explain how to clone, manipulate, analyze, and sequence large segments of DNA, and relate sequence to phenotype variation. Techniques, written for human as well as other animal genomes, deal plainly with sources of failure and how to avoid them. Protocols are written by experts, often by those who created the methods. The series is an excellent complement to the bible of recombinant DNA, Molecular Cloning.
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 | G5039 | Genome Analysis: Laboratory Manual Series Volume 3: Cloning Systems | Assuming only a basic knowledge of molecular biology, these manuals explain how to clone, manipulate, analyze, and sequence large segments of DNA, and relate sequence to phenotype variation. Techniques, written for human as well as other animal genomes, deal plainly with sources of failure and how to avoid them. Protocols are written by experts, often by those who created the methods. The series is an excellent complement to the bible of recombinant DNA, Molecular Cloning.
Topics include Bacterial Cloning Systems; Cosmids; Cloning into Bacteriophage P1 Vectors; OBacterial Artificial Chromosomes; and Yeast Artificial Chromosomes
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 | Z382698 | Genome Analysis: Laboratory Manual Series Volume 4, Mapping Genomes | Topics include
Meiotic Mapping in Humans;
Genetic and Comparative Mapping in Mice;
Identification and Analysis of DNA Polymorphisms;
DNA Markers for Physical Mapping;
Representational Difference Analysis;
Somatic Cell Genetics and Radiation Hybrid Mapping;
Fluorescence In Situ Hybridization
Assuming only a basic knowledge of molecular biology, these manuals explain how to clone, manipulate, analyze, and sequence large segments of DNA, and relate sequence to phenotype variation. Techniques, written for human as well as other animal genomes, deal plainly with sources of failure and how to avoid them. Protocols are written by experts, often by those who created the methods. The series is an excellent complement to the bible of recombinant DNA, Molecular Cloning.
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 | G7541 | Genome Visualization by Classic Methods in Light Microscopy | In a two column format, the author investigates the classic techniques employed in the visualization of nucleic acids by light microscopy. The book discusses the chemical structure of nucleic acids, general principles of staining, nuclear dyes, and histochemical methods. Each chapter features different methods of staining, along with chemical principles and protocols. It also contains a color section with examples of observations.
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 | Z730335 | Genomes 3 | Genomes 3 builds on the achievements of the previous two editions by putting genomes, rather than genes, at the center of molecular genetics teaching. Recognizing that molecular biology research was being driven more by genome sequencing and functional analysis than by research into genes, this approach has gathered momentum in recent years. The artwork has been entirely re-drawn with the emphasis throughout on simplicity and scientific consistency. This edition includes two new chapters on genome anatomies, covering the latest sequencing achievements; new chapter on genome function, to describe the latest technologies used in studying the transcriptome and the proteome; new chapter on recombination, providing expanded coverage of genome evolution; Free CD-ROM of the artwork supplied with every copy.
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 | G0793 | Genomics Protocols | This book contains a comprehensive generic set of protocols for gene hunting and genome analysis. Drawing on emerging technologies in the fields of bioinformatics and proteomics, these protocols cover traditional genomics, and early therapeutic approaches exploiting the potential of gene therapy. Highlights include methods for the analysis of differential gene expression, SNP detection, comparative genomic hybridization, and the functional analysis of genes, as well as the use of bioinformatics for gene identification and the prediction of protein function.
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 | Z379662 | Glycoanalysis Protocols (2nd ed.): Methods in Molecular Biology, Vol. 76 | A compendium of structure elucidation techniques for scientists in the areas of glycoproteins, lipoproteins, proteoglycans, and complex carbohydrates. Includes oligosaccharide profiling, macromolecular structural analysis, and microorganism structure determination. Special attention is given to analysis of recombinant glycoproteins as therapeutics.
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 | Z730130 | Glycobiology Protocols | A panel of experts reviews the importance of glycobiology. This book highlights important methodological progress that has been made in the field of glycobiology, helping scientists to answer specific questions on glycoprotein structures, on the biosynthesis of glycoconjugates, and on the functions of lipid- or protein-bound carbohydrates. This book contains specific methods for the analysis of the structures or functions of glycoconjugates, as well as of glycosyltransferases and glycosidases involved in the biosynthesis of glycans. The methods described for specific systems can be modified for investigations of similar biomolecules and tissues or cell types. This book provides researchers with a solid basis for studying the many aspects of glycobiology with state-of-the-art methods.
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 | G2793 | Gold and Silver Staining: Techniques in Molecular Morphology | Immunogold silver staining is one of the most sensitive techniques for visualizing the location of antibodies and nucleotide probes. Contributors cover the latest developments and a range of applications from highly sensitive detection of antigens to single copy detection of DNA and RNA. This book presents descriptions that allow visualization of molecules never localized before. It also provides a selection of protocols with high sensitivity; presents techniques for cytochemistry, histochemistry, in situ hybridization, and immunoblotting applications; discusses the applications to cancer research; offers suggestions, tips, and guidelines to avoid unspecific precipitations; analyzes advantages and drawbacks of staining methods.
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 | G9528 | Golden Helix: Inside Biotech Ventures | This candid narrative by Nobel laureate, Arthur Kornberg, chronicles the saga of a small biotech firm’s start-up, the key players, the painstaking development of the perfect product, and the forces affecting its resulting success or failure. Kornberg's razor-sharp wit and provocative opinions make this book a compelling page turner, whether he is decrying the current fashion in scientific funding or delving into the hotly contested PCR patent trial.
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 | G6417 | Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 10th ed. | Thoroughly updated by authors who are experts, this edition continues the tradition of being the best available text and reference source for information on the actions and uses of drugs. Well organized, extensively indexed, and reference to the most up-to-date literature in the field. It remains the premier reference for physicians, pharmacists, and medical pharmacy students. New edition covers the latest developments in molecular pharmacology and clinical developments on the newest agents.
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 | G9524 | GraFit™ | GraFit 6.0 combines presentation-quality scientific graphs with comprehensive data fitting. The result is a powerful package that is easy to use, produces stunning output, and can also fulfil the needs for quantitative data analysis. Data can be fitted using various types of theoretical models, and your own equations can easily be added to those supplied with the program. Comprehensive graph plotting facilities allow you to display your data on-screen and edit the graphs interactively.
GraFit provides the experimental scientist with a tool for visualization and analysis of their data. For the occasional user, GraFit can be configured to perform routine analyses with minimal intervention. In many cases it is possible just to enter the data and allow GraFit to calculate the results and plot the graphs in the background. Advanced users can utilize the full power of GraFit for analyzing complex equations, and may create custom fitting templates for routine data processing.
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| | Z359777 | Grant application writer’s handbook | This book illustrates how to plan and develop a good proposal and explains what reviewers look for in applications. Information is provided on private foundation proposals and on oral presentations. Advice presented will be useful for writing many types of grant applications, business plans, journal articles and research reports.
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 | Z730653 | Green Chemistry and Engineering | Green Chemistry is the utilization of a set of principles that reduces or eliminate the use or generation of hazardous substances in design of chemical processes. Due to extravagant costs needed to managing these wastes, tens of billions of dollars a year, there is a need to propose a way to create less waste. Emission and treatment standards continue to become more stringent, which causes these costs to continue to escalate. This book describes both the science (theory) and engineering (application) principles of Green Chemistry that lead to the generation of less waste. It explores the use of milder manufacturing conditions resulting from the use of smarter organic synthetic techniques and the maintenance of atom efficiency that can temper the effects of chemical processes. By implementing these techniques means less waste, which will save industry millions of dollars over time.
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 | G3793 | Green Fluorescent Protein: Applications and Protocols | This book demonstrates the power and the versatility of the green fluorescent protein (GFP) marker with a cutting-edge collection of readily reproducible GFP techniques. These include methods for detecting and imaging GFP (FRET, BRET, and whole-body imaging); for using GFP to create and select for transgenic organisms, for its use as a biosensor; and for studying viruses. A valuable companion CD-ROM displays many color figures and videos from over half the chapters.
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 | Z705217 | Green Fluorescent Protein: Properties, Applications and Protocols, 2nd ed. | This text tackles both theory and practice, offering numerous case studies, examples, illustrations, and troubleshooting tips. It examines how Ps are tailored for specific systems and used to maximize expression, and how variants are generated with altered properties. The text also explores new ways to use FPs and methods for enhancing detection in a variety of organisms and cell types. This updated and expanded edition places emphasis on the rise of FPs and their applications in industry and biosensor research. It provides new chapters on FPs, biosensors, and advances in the use of FPs in the biotechnology and pharmaceutical industries, detailed information about protocols using FPs, and three-dimensional structure, and molecular biology and mutation of FPs.
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 | Z705942 | Greene’s Protective Groups in Organic Synthesis 4th ed. | Greene's Protective Groups in Organic Synthesis, Fourth Edition, provides the only comprehensive guide to this topic available. Techniques for formation and cleavage of protective groups are provided, along with a useful reactivity chart and sections on potential undesired side reactions. The Fourth Edition has been updated to include 1,350 protective groups and over 8,000 references to the primary literature. It is an indispensable reference for any practicing synthetic organic or medicinal chemist.
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| | Z510726 | Grignard Reagents: New Developments | Details new reactions and applications of organomagnesium compounds. Focuses on stereoselective reactions, industrial applications, and strategy.
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| | G4789 | Growth Factors and Receptors: A Practical Approach | Provides comprehensive protocols for studies of growth factors and their interactions with receptors. Describes important novel approaches, such as the use of RNA aptamers as receptor antagonists, and the development of receptor superantagonists. Covers a wide range from simple analytical techniques to sophisticated in vivo applications including:
• RT-PCR and immunocytochemistry for detection of growth factors and receptors
• Production and purification of recombinant growth factors and receptors
• Labeling of growth factors for binding studies
• Yeast two-hybrid assay of protein-protein interactions
• Analysis of important factor domains using chimeric proteins
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| | Z350044 | Growth Factors: A Practical Approach | This manual is a step-by-step guide to studying growth factors from the initial search for and characterization of new activities, to sophisticated in vivo analysis and molecular biology approaches, such as DNA cloning.
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 | Z701920 | Growth and Lactogenic Hormones: Neuroimmune Biology Vol. 2 | For seventy years evidence has accumulated documenting the existence of a bi-directional communication network between growth hormone and the immune system. In the past twenty years there has been a tremendous proliferation of information detailing the workings of the growth hormone and insulin-like growth factor axis. A multitude of growth factors and binding proteins have been identified. More evidence supporting the important role of the growth hormone IGF network in the well functioning of the normal immune system has been documented. The challenge today is not to prove, but to understand, the neuroimmune regulatory role of GLH in its entire complexity.
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 | Z702544 | Guide to Analysis of DNA Microarray Data, 2nd ed. | Written for those who don't have any special training in data analysis and statistics, this book begins where DNA array equipment leaves off: the image produced by the microarray. The text deals with the questions that arise starting at this point, providing an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond. This book offers practitioners reliable information using concrete examples and a clear style. This edition features entirely new chapters on Image analysis; Experiment design; Automated analysis, integrated analysis, and systems biology; Interpretation of results .
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| | Z285803 | Guide to Materials Characterization and Chemical Analysis, 2nd ed. | Written both for the novice and for the experienced scientist, this miniature encyclopedia concisely describes over one hundred materials methodologies, including evaluation, chemical analysis, and physical testing techniques. Each technique is presented in terms of its use, sample requirements, and the engineering principles behind its methodology. Real life industrial and academic applications are also described to give the reader an understanding of the significance and utilization of technique. There is also a discussion of the limitations of each technique.
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 | Z369268 | Guide to Spectroscopic Identification of Organic Compounds | This is a practical “how-to” book for determining molecular structure from spectral data obtained MS, IR, NMR or UV spectrophotometers. Representative compounds are analyzed and examples are solved. A picture of the relationship of structure to physical properties, as well as spectral features, is provided.
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 | Z700452 | Guide to Yeast Genetics and Molecular and Cell Biology, Part B, Methods in Enzymology Vol 350 | This volume and its companion, Volume 351, are specifically designed to meet the needs of graduate students as well as researchers, by providing all the up-to-date methods necessary to study genes in yeast. Procedures are included that enable anyone to set up a yeast laboratory and to master basic manipulations. Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines. Specific topics addressed in this book include basic techniques, making mutants, genomics, and proteomics.
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 | Z700460 | Guide to Yeast Genetics and Molecular and Cell Biology, Part C, Methods in Enzymology Vol 351 | This volume and its companion, Volume 350, are specifically designed to meet the needs of researchers, by providing all the up-to-date methods necessary to study genes in yeast. Procedures are included that enable anyone to set up a yeast laboratory and to master basic manipulations. Relevant background and reference information given for procedures can be used as a guide to developing protocols in a number of disciplines. Specific topics addressed in this book include cytology, biochemistry, cell fractionation, and cell biology.
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 | Z379972 | Guide to the Polyamines | A comprehensive survey of the physiological and structural functions of biological polyamines. Both normal and pathological functions are covered, the latter represented especially by cancer, viral infection, and protozoan parasitism. There is extensive coverage of the role of polyamines in polynucleotide organization.
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 | Z378070 | Guidebook to Protein Toxins and Their Use in Cell Biology | Toxins are presented in groups according to their modes of action and cellular effects. Groups include membrane-permeabilizing toxins, toxins affecting signal transduction and protein synthesis, cytoskeletal toxins, toxins affecting membrane traffic, toxins that target ion channels, and presynaptic toxins.
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| | Z364215 | Guidebook to the Secretory Pathway | Addresses many aspects of the secretory pathway with almost two hundred entries. Provides succinct, up-to-date information with short bibliographies regarding cell-cycle control and membrane traffic.
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