This edition contain revisions, updates, and expansions include Structure and Functions of Common Drugs, Solubility Parameters of Polymers, Major World Earthquakes, and Equilibrium Constants of Selected Enzyme Reactions. It adds major updates to several more, including Threshold Limits for Airborne Contaminants, Mass Spectral Peaks of Common Organic Solvents, and Properties of the Solar System.
Casarett and Doull’s Toxicology: The Basic Science of Poisons, 7th edition
The new edition discusses areas of apoptosis, cytokines, growth factors, oncogenes, cell cycling, transcription factors, signaling pathways, and genomics.
This book is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by an expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs.
Green Chemistry is the utilization of a set of principles that reduces or eliminate the use or generation of hazardous substances in design of chemical processes. Due to extravagant costs needed to managing these wastes, tens of billions of dollars a year, there is a need to propose a way to create less waste. Emission and treatment standards continue to become more stringent, which causes these costs to continue to escalate. This book describes both the science (theory) and engineering (application) principles of Green Chemistry that lead to the generation of less waste. It explores the use of milder manufacturing conditions resulting from the use of smarter organic synthetic techniques and the maintenance of atom efficiency that can temper the effects of chemical processes. By implementing these techniques means less waste, which will save industry millions of dollars over time.
This handbook compiles the most comprehensive information on over 200 water-based and solvent-based indicators. Organized alphabetically, entries include: common name, other names, CA index name, CAS registry number, Merck index number, chemical structure, chemical/dye class, molecular formula, molecular weight, pH range, color change at pH, pKa, physical form, solubility, UV-visible, melting point, and boiling point. This resource also offers unique coverage including protocols for synthesizing indicator compounds; data relating to adverse effects, toxicity, and major applications for each indicator. The handbook contains practical information for applications that include semiconductors, fuel cells, sensors, surface coatings, adhesives, agricultural chemicals, textiles, personal care products, pharmaceuticals, and detection of disease.
This book presents the latest research and technology in the field and considers major issues and challenges in the production of commercial-scale polymers. It reviews fundamental concepts in polymer chemistry including the polymerization mechanisms, catalysts, monomers, solvents, and agents to prepare a variety of different types of polymers, and also studies the reaction parameters that are key to the control of polymerization rates, polymer molecular weight, molecular weight distribution, and structural stability This second edition examines the advantages and limitations of a variety of polymerization applications and procedures, as well as new approaches and innovative strategies from the most prominent industry and academic laboratories.
This handbook contains comprehensive information on more than 5,500 trade names and generic chemicals and materials that are used in a broad range of formulations to prevent the contamination and decomposition of end products. Product degradation can be caused by exposure to oxygen, ozone, bacteria, molds, yeast, mildew, and fungi. The industries that depend on the proper selection of preserving chemicals and materials are diverse and include: plastics, elastomers, construction, paper/pulp, agriculture, textiles, paints and coatings, pharmaceutical, cosmetics, food, beverages.
This handbook contains comprehensive information on preservatives available from chemical manufacturers and will expedite the material selection process for chemists, formulators and purchasing agents by providing the answers to these questions:
• Is the agent capable of inhibiting the detrimental effects of oxygen, ozone, or microbes to the extent necessary? • Is the agent's overall physical and chemical attributes compatible with the product or system being protected? • Can the agent remain stable under storage conditions and for the application requirements? • Is its safety in production and handling acceptable? • Does its level of toxicity meet environmental regulations? • Does it meet cost requirements?
Trade name entries contain detailed information provided by the manufacturers and are cross referenced by chemical composition, application, CAS and EINECS numbers. Generic chemicals that either function as preservatives or are part of the trade name product's composition are also included with extensive monographs. Suppliers of the trade names and chemicals are listed with full contact information
The 15th Edition is a compilation of technical data and descriptive information covering thousands of chemicals and chemical phenomena, trade name products, processes, reactions, products, and related terminology. It includes updates and expands the coverage from the previous edition, adds entries for notable chemists and Nobel Prize winners, equipment and devices, natural forms and minerals, named reactions, and chemical processes. It provides concise, condensed, and prompt definitions of terms and phenomena in chemistry, biology, biochemistry, and more. This book is ideal for those with only minutes to devote to any given chemical substance or topic
In this delightfully designed book, K. C. Nicolaou introduces the world's most important molecules and shows in a fascinating way the role certain compounds have to play in our everyday lives in the fields of drugs, aromatics or vitamins. For example, he tells the story of Aspirin, beginning 3,500 years ago in Egypt, through to its first synthesis and various applications with many entertaining facts and details. Printed in full color throughout and with its oversize format, this is a must for every chemist, natural scientist and anyone interested in the sciences.
Readers will find that this highly acclaimed book offers a balanced approach to functional groups and mechanisms. The clear, accessible presentation of key concepts will help them master basic skills. Throughout the pages, the focus is placed on the important ideas of organic chemistry and backs them up with illustrations and challenging problems. The new ninth edition also incorporates more biomedical examples and modern reactions, as well as integrated media for practice and assessment.
This reference guide will lead you to the most important recent developments like how scientists can now prepare ketones by directly combining aldehydes with terminal alkenes. Also, detailed analysis of more than twenty total syntheses, including the Davies Synthesis of (-)-Colombiasin A and (-)-Elisapterosin B, the Overman Synthesis of (-)-Sarain A, and the Sorensen Synthesis of (-)-Guanacastepene E.
This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book
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