The Biology of Cancer synthesizes the findings of three decades of recent cancer research and proposes a conceptual framework from which to teach about these discoveries. It provides the necessary structure, organization, and content for a course on cancer biology for advanced undergraduates and beginning doctoral students.
The book is comprehensive and offers many pedagogical features to assist teaching and learning. The text provides current information on topics such as tumor stem cells and recently introduced chemotherapeutics. State-of-the-art techniques are discussed throughout. Modern biomedical research is explored, helping readers to hone their analytical abilities and to assimilate and think clearly about complex biological processes.
This book presents current advances in the application of microarray technology to the most active areas of cancer research, elaborating on the importance of this technology for understanding the causes of cancer and future treatment possibilities. It presents the first step on the path toward key discoveries that will lead to a better understanding of the causes of cancer, new biomarkers and drug targets. Topics addressed include: spotted array production, synthesized arrays with cancer applications, tissue collection for microarrays, microarray analysis of solid tumors, and bioinformatics in micorarray expression analysis technology
This second edition is now in a larger format that has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It continues to provide a detailed overview of the process which lead to the development and proliferation of cancer cells, including the techniques available for their study. It also describes the means by which tumor suppressor genes and oncogenes may be used in the diagnosis and in determining the prognosis of a wide variety of cancers, including breast, genitourinary, lung and gastrointestinal cancer.