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Z703028B Cell Protocols Recent advances in genetics, synergized by many exciting developments in cellular and molecular biology, have provided powerful new experimental tools for the study of not only B-lymphocyte development and function, but also the physiology and pathology of the immune system in higher animals. This book is a diverse collection of protocols ranging from the latest inventions and applications to some classic, but still frequently used, methods in B cell biology. These readily reproducible protocols follow the successful Methods in Molecular Biology series format.
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B7157Baculovirus Expression Vectors: A��Laboratory Manual This laboratory manual simplifies the selection of the most appropriate vector design for a given problem and describes each step in the implementation process from vector construction to large-scale protein production.
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Z731293Bailey & Scott’s Diagnostic Microbiology 12th ed. The 12th edition features the same comprehensive, authoritative content and adds new and updated material throughout. Detailed hands-on procedures make the content more interesting and relevant by describing exactly what takes place in the micro lab. There are 3 new chapters along with general considerations and applications of information provided in Bacterial Sections of Part III which explains the criteria for organism inclusion and how it should be used. This guide to Part III includes gram reaction, shape, arrangement, atmosphere preferred, oxidase and catalase reactions, among other decision points for various pathogens, creating a visual method of identifying and cross referencing organisms.
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B7058Bailey & Scott’s Diagnostic Microbiology, 11th ed. The classic text known as the 'gold standard' in microbiology is now revised, reorganized, and up-to-date. Always comprehensive and current, this edition features even more new information on hot topics such as identification systems, quality control organisms, antiparasitic agents, HIV viral load testing, HIV genotyping, Hepatitis C virus, antivirals, and a new procedure for the motility test. The additional and revised material reflects the latest advances and developments. New clinical case studies challenge students to think critically and apply what they've learned in realistic situations.
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Z702919Basic Cell Culture Protocols 3rd ed. This third edition offers today's most comprehensive collection of easy-to-follow, cutting-edge protocols for the culture of a wide range of animal cells. Its authoritative contributors provide explicit, step-by-step instructions, along with extensive notes and tips that allow both experts and beginners to successfully achieve their desired results. Topics range from basic culture methodology to strategies for culturing previously uncultured cell types and hard-to-culture differentiated cells. Methods are also provided for the analysis of living cells by FACS, video microscopy, and confocal microscopy. This book should be in every cell culture laboratory and be of use to all who use cell cultures in research
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B2183Basic Cell Culture: A Practical Approach, 2nd ed. This book is a guide to all those areas which are currently basic to the performance of animal (including human) cell culture. Experienced and novice researchers should find this book useful as a source of reference, when entering a new field, or when setting up a new laboratory.
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 500003Basic Gas Chromatography This book is a product of three basic gas chromatographic courses that Varian Aerograph offers throughout the world. Useful data are presented, including calibration factors for detectors, chemical structures of liquid phases, and methods for preparing liquid phases and packing columns. The authors hope readers will confirm their belief that a major advantage of GC is its simplicity.
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 Z406406Basic Gas Chromatography: Techniques in Analytical Chemistry Offers thorough coverage of basic principles and techniques of modern gas chromotography, serving as a primer/working reference for bench chemists and as a text for upper-level undergraduate and graduate students. Theoretical issues are explained without complicated equations and derivations and always in terms of how they relate to practical operating principles. Coverage includes both capillary column and packed column chromotography, as well as cutting-edge topics such as chiral analysis and solid phase microextraction. Includes step-by-step guidelines and trouble shooting tips, reference appendices, and use of new IUPAC terms cross-referenced to traditional terms and symbols. From Book News, Inc., Portland, OR
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 Z350281Basic Laboratory And Industrial Chemicals: A��CRC Quick Reference Handbook This handbook presents data on 1,000 high profile chemical substances commonly used in the laboratory and workplace. It provides information on physical, thermodynamic, and transport properties of chemicals.
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B4931Basic Methods in Antibody Production and Characterization This manual uses a cookbook approach to presenting the methods for the production, characterization, and use of antibodies. Antibodies described include polyclonal and monoclonal and those made by the phage display. It focuses on specific aspects of antibodies and takes readers on a step-by-step process from antigen preparation to immunizations, adjuvants, screening, purification, storage, and applications. Ample references provide researchers with many applications pertaining to the technology.
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Z719102Basic Methods in Microscopy Imaging has become a vital tool for researchers in all aspects of biology. Recent advances in microscope technology, labeling techniques and gene and protein manipulation methods have led to breakthroughs in our understanding of biological processes. In order to take advantage of these techniques, biologists need to understand the fundamental techniques of microscopy. The methods found here, drawn from the popular laboratory standard manuals Cells: A Laboratory Manual and Live Cell Imaging provide a solid course in the basics of using the microscope in a biology laboratory. This book provides an essential guide to light microscopy, fluorescence microscopy, confocal microscopy, multiphoton microscopy and electron microscopy, preparation of tissues and cells, labeling of specimens and analysis of cellular events.
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 Z357332Basic Methods in Molecular Biology, 2nd��ed. pricing
 B5678Basic Molecular Biology: Essential Techniques Begins with a brief overview and then focuses on simple step-by-step protocols of the core techniques. It provides not only a theoretical outline, but also valuable advice on real-world problems and estimates on how much time is required to perform each technique.
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Z703311Basic One- and Two-Dimensional NMR Spectroscopy, 4th Completely revised edition A classic among NMR textbooks, this thoroughly enlarged and updated fourth edition includes polymer solid state NMR, analysis of biopolymers, and applications of Magnetic Resonance Tomography and Magnetic Resonance Spectroscopy. Written by an NMR expert with long-standing teaching experience, this text provides students and professionals with a lucidly written introduction to NMR spectroscopy. The book forms an excellent bridge between the very simple texts on spectral interpreataion and more specialist works with an emphasis on mathematical theory.
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Z704903Beacon Designer Beacon Designer helps design successful SYBR™ Green, TaqMan™, LNA spiked TaqMan, molecular beacon for both standard and NASBA assays and FRET assays by interpreting BLAST results for specificity and locating oligos avoiding template structures.
SYBR Green Primer Design- Highly specific primers are designed by avoiding significant homologies found by automatically interpreting BLAST search results. Primer efficiency is enhanced by avoiding template secondary structures identified by connecting to the Mfold server.
Dual Labeled Probe Design: Dual-labeled fluorescent TaqMan, molecular beacon or FRET probes can be designed with the help of Beacon Designer. For these assays, you can design new primers and probes or find probes compatible with previously designed SYBR Green assays and save on synthesis costs.
TaqMan probes and Molecular Beacon Multiplex experiments- Multiplex assays are designed by avoiding homologies with all primers and probes in the pool. This prevents competition in multiplex real time PCR reactions and assures high signal strength.
Allelic Discrimination- Design both wild and mutant probes for SNP genotyping assays.
LNA Probe Design- In addition to standard TaqMan probes, Beacon Designer also designs the increasingly popular LNA or Locked Nucleic Acid substituted TaqMan probes to improve real-time PCR assay success.
NASBA Assays- Beacon Designer designs molecular beacon probes for NASBA assays for single template, multiplex or alleleic discrimination.
BLAST Search- Both primers and templates/amplicons can be BLAST searched against genomic databases available at NCBI or against local custom databases. This function helps verify the primer specificity.
Avoid Template Structures- Automatically avoid secondary structures in the template identified by connecting to the Mfold server while designing primers.
Generate Report- Generate an attractively formatted
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B3184Before & Beyond Patents This guide provides answers to frequently asked questions on topics such as - Becoming an inventor; Managing inventions and discoveries - step-by-step; Inventions - Rights of collaborators and young scientists; Rights of co-inventors; Effects of disclosing research results before protecting patent rights; How sharing and transfer of biological materials affects patent rights; Inventions and how to go about setting up a business.
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Z700843Beginner’s Guide to Microarrays The manufacture, experimental design, and analysis of microarrays are not always straightforward, and researchers run into roadblocks that hinder progress. This book is directed to the core facility manager who produces, hybridizes, and scans arrays, and the research scientist who will be performing the analysis and interpreting the results. It provides a user friendly coverage and protocols for the technical steps and procedures involved in many facets of microarray technology, including: Coating glass slides; Designing oligonucleotide probes; Troubleshooting spotting problems; Normalizing background signal and controlling for systematic variance; Analyzing data with statistical procedures.
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B0411Bergey’s Manual of Determinative Bacteriology, 9th��ed. Based on the data contained in the four-volume Bergey's Manual of Systematic Bacteriology, this book also includes new genera and species, new combinations, and new taxa published through the January 1992 issue of the IJSB. Users will find short general descriptions that encompass all organisms by Groups; shape and size, Gram reaction, other pertinent morphological features, motility and flagella, relations to oxygen, basic type of metabolism, carbon and energy sources, habitat and ecology. BMDB-9 also includes discussions of difficulties in identification, keys or tables to genera and species, genus descriptions, synonyms, other nomenclatural changes, and numerous illustrations.
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B8305Beyond Neurotransmission This book provides the foundations for understanding the cellular and molecular basis for neuromodulatory effects. It illustrates key examples of the roles played by neuromodulation in sensory processing, neuromuscular transmission, generation of motor behaviors, and learning. The book also underscores the importance of information processing by the nervous system in future studies. By spanning the levels of analysis from sub-cellular mechanisms through cellular properties and neuronal systems to behavior, the book provides a framework for understanding this field.
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Z730084Binding and Kinetics for Molecular Biologists This handbook offers a practical guide to the principles of quantitative analysis in biological experiments. The material is primarily aimed at working molecular biologists, but the scope and clarity of presentation make it equally suitable for students. Topics covered range from the basics—such as measuring the concentrations of macromolecules—through considerations of binding constants and the kinetics of molecular interactions. The book ends with a thorough consideration of data analysis.
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Z702625Bio conjugation Protocols: Strategies and Methods Experts update the classic bioconjugation methods and introduce techniques that go beyond pure biomedical applications to include elements from organic synthesis, molecular biology, and materials science. These methods cover the preparation of protein conjugates using covalent and noncovalent conjugation, the synthesis of nucleic acid conjugates using a variety of labeling techniques, and approaches to semisynthetic conjugates of proteins. Additional chapters address on-chip synthesis to generate microarrays for the high-throughput analysis of RNA and DNA.
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Z700541BioNMR in Drug Research This book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids. BioNMR spectroscopy offers a universal tool for examining the binding of an active substance to its target protein. Its use benefits the rational development of drugs. This interaction can now be investigated and displayed in 3D - an important prerequisite for the targeted development of new active substances. The latest methods for characterizing substance-receptor complexes are demonstrated backed by case studies from pharmaceutical research. This guide contains basic information, application strategies and real-life examples.
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Z702951Bioanalytical Chemistry Bioanalytical Chemistry reviews all relevant aspects of using analytical methodology to solve biological problems. Each chapter in the book begins with coverage of basic concepts, then progresses to applications that involve real samples. This book covers: Spectroscopic methods for matrix characterization; Structural and functional properties of antibodies; Principles of electrophoresis; Centrifugation methods; Mass spectrometry of biomolecules; Quantitation of enzymes and their substrates; Design and implementation of enzyme assays; Isoelectric focussing; Chromatography of biomolecules; and Validation of new bioanalytical methods.
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Z704768Biocatalysts and Enzyme Technology A comprehensive overview of current knowledge of biocatalysis and enzyme technology. Following an introduction to the history of enzyme applications and the motivations for using these highly selective and environmentally friendly methods, the book goes on to cover enzyme mechanisms and kinetics, production, recovery, characterization and their design, including recombinant methods. Alongside the application of soluble and immobilized biocatalysts, including whole-cell systems, the authors treat the use of non-aqueous reaction systems, applications in organic synthesis, bioreactor design and reaction engineering. In line with the book's didactic approach, a number of case studies further exemplify the advantages of enzyme processes. Each topic includes exercises, designed to facilitate access to this area of research.
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B1933Biochemical Methods:A Concise Guide for Students and Researchers This book is the completely revised and updated English version of the very successful German language textbook, Methoden der Biochemie. It refers to laboratory equipment and safety aspects and explains how to obtain relevant biochemical information. It provides an introduction into physical-chemical processes and mathematical methods required for the interpretation of data. Principles of expensive instrumental analysis are also explained. In particular the presentation of safety considerations and regulatory issues has been adapted according to international requirements. It also contains a CD-ROM on quantitative analysis of biochemical experiments.
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B9911Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology This truly unique road map to modern biochemistry is an atlas of multi-step reactions in biological systems. The book graphically represents this network of reactions with a series of chemical formulas along with two-dimensional spatial arrangements demonstrating each molecule's cellular, organic, and structural aspects. It is an encyclopedic, comprehensive, and clearly organized reference for any biochemist.
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B6308Biochemistry of Cell Signalling This will serve as a reliable map through the maze of cell signaling pathways and help the reader understand how malfunctions in these pathways can lead to disease. Part 1 describes the machinery of signal transduction starting with the properties of signals, receptors (including receptor activation), regulators, and the molecules that link receptor and regulator. Part 2 describes the implementation of the signaling cascades focusing on the effect on gene transcription. Part 3 studies the global cellular regulatory programs for the control of cell growth and proliferation. Part 4 considers loss of regulatory control and its consequences with respect to the molecular basis of cancer.
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Z701297Biochemistry of Signal Transduction and Regulation, 3rd ed. This book has become the "gold standard" in the field of signal transduction and offers unmatched quality from the pen of a single author. The author succeeds in balancing comprehensive coverage with a clear and didactic style. The new edition is completely updated. 50% of the content has been rewritten to incorporate recent findings, and many illustrations have been redrawn and are now presented in full color.
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Z731390Biochemistry of Signal Transduction and Regulation, 4th ed. This all-new edition of a best-selling text has been thoroughly updated to keep pace with the rapid progress in signal transduction research. With skill and clarity, the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis is made transparent for everyone with a basic knowledge in biochemistry or molecular biology. "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)
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B6933Biochemistry, 5th ed. With the addition of two new co-authors, Biochemistry takes a new direction, as it becomes the first text to fully reflect the revolution that has taken place in biomedical science in the past ten years, culminating in the human genome project. A key focus of the new edition is the unifying features of protein structure and function that have been revealed by the incredible progress in gene sequencing. The fifth edition is the first edition to be fully integrated with multimedia. The Conceptual Insights and Structural Insights Tutorials, written by Neil D. Clarke, as well as the Living Figures are all identified in the text by a special media icon
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Z700444Biochemistry:The Chemical Reactions of Living Cells, 2nd ed., Vol. 1 The most comprehensive textbook/reference ever to cover the chemical basis of life, the "Green Bible of Biochemistry" has been a well-respected contribution to the field for more than twenty years. The complex structures that make up cells are described in detail, along with the forces that hold them together, and the chemical reactions that allow for recognition, signaling and movement. There is ample information on the human body, its genome, and the action of muscles, eyes, and the brain. The complete set deals with the natural world, treating the metabolism of bacteria, toxins, antibiotics, specialized compounds made by plants, photosynthesis, luminescence of fireflies, among many other topics.
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Z703559Biocomputing: Computer Tools For Biologists BioComputing: Computer Tools for Biologists contains a selection of BioTechniques' best Biocomputing papers from 1996-2002 augmented with original author updates. This comprehensive collection provides researchers with simple programs and open source code that can be used as models to study, copy, and modify for developing new computer programs. It also contains useful tools and insights into how to design better queries and interpret results more carefully, thus making more effective use of websites such as BLAST and PubMed.
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Z374210Bioconjugate Techniques A practical guide to modification and cross-linking technology for research, diagnostics and therapeutics. Contains detailed information on the chemistry, reagent systems and practical applications for creating labeled or conjugated molecules.
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 Z269662Biodegradable Hydrogels for Drug Delivery This book provides an in-depth investigation of recent advances in biodegradable hydrogels. Based on extensive research and experience, the book is the first to deal exclusively with this important area in drug delivery. A valuable guide for all, the book begins with a detailed introduction to current biodegradable hydrogel technology. Following chapters present advanced R&D, delivery systems, and more. It covers the mechanisms of biodegradation, types of biodegradable hydrogels, chemical and physical gels, chemical and enzymatic degradation, and examples of biodegradable drug delivery systems.

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Z705004Biofunctionalization of Nanomaterials Nanotechnologies for the Life Sciences (NtLS) is the first comprehensive source covering the convergence of materials and life sciences on the nanoscale. Tailor-made nanomaterials find widespread new opportunities in diagnostic and monitoring microdevices, microsurgery tools and instruments, tissue engineering, drug delivery artificial organs and any more. NtLS is essential reading for all scientists working in this field from medicine and biology through chemistry, materials science and physics to engineering. Volume 1 brings together the synthetic methods and materials aspects of instilling biocompatibility and desirable properties into nanomaterials, covering numerous types and methods.
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B5056Bioinformatics Basics: Applications in Biological Science and Medicine Scientists use an extensive databank to access structural information on proteins and nucleic acids and a specialized form of software to analyze the hybridization pattern of DNA chips. The success of biotechnology and pharmaceutical industries has been a result of technical advancements in genomics, proteomics, and bioinformatics. This book describes the organization of public domain databases with a tutorial for the services described. It concentrates on three major database clusters and relevant software tools that are maintained in the US, Europe, and Japan.
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Z704415Bioinformatics and Drug Discovery A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates. The authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situations. Because these technologies are still emergent, each chapter contains an extended introduction that explains the theory and application of the technology and techniques described.
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Z701718Bioinformatics and Functional Genomics Encompassing the field of bioinformatics, from sequence analysis, gene expression, microarrays, and proteomics to molecular phylogenics and whole genome studies, this text shows how bioinformatics applies to biological questions at different levels, such as gene/protein, disease, and protein structures. The author emphasizes practical skills, such as how to analyze genes and proteins, how to make trees using phylogenic software, how to extract data, and how to identify genes and proteins implicated in disease. It provides a systematic three-part format, beginning with the analysis of biological sequence data, continuing with functional genomics (from microarrays to proteomics), and ending with coverage of genomes.
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Z730386Bioinformatics for Dummies 2nd ed. Explore the human genome and analyze DNA — without leaving your desktop! All it takes is the basics of molecular biology and the wealth of information in this friendly guide. You'll discover the online tools and useful tips you need to ask the right questions, analyze sequences, and compare results. It's a plain-English introduction to the field! Discover how to do biological research online; Use gene-centric databases; Visualize proteins in 3-D; Interpret and analyze sequences; Produce and publish results.
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Z703591Bioinformatics: A Guide to the Analysis of Genes and Proteins, 3rd ed. Using relevant biological examples, the book provides background on and strategies for using many of the most powerful and commonly used computational approaches for biological discovery. This new edition features new chapters on genomic databases, predictive methods using RNA sequences, sequence polymorphisms, protein structure prediction, intermolecular interactions, and proteomic approaches for protein identification. It contains detailed worked examples illustrating the use of the concepts presented. Special topic boxes and appendices highlighting experimental strategies and advanced concepts are included with annotated reference lists, comprehensive lists of relevant Web resources, and an extensive glossary of commonly used terms in bioinformatics, genomics, and proteomics
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B2931Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, 2nd ed. The second edition covers the broad spectrum of topics in bioinformatics, ranging from Internet concepts to predictive algorithms used on sequence, structure, and expression data. It includes: (a) all new end-of-chapter Web resources, bibliographies, and problem sets, (b) accompanying Website containing the answers to the problems, as well as links to relevant Web resources, (c) new coverage of comparative genomics, large-scale genome analysis, sequence assembly, and expressed sequence tags, (d) a glossary of commonly used terms in bioinformatics and genomics.
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B8308Bioinformatics: From Genomes to Drugs, 2 Volume Set Bioinformatics promises to revolutionize the process of drug discovery and development. This book provides an application-oriented overview of this technology. In addition, the state-of-the-art in bioinformatics is evaluated from a global view by introducing real application scenarios such as genome projects that require the use of a whole set of bioinformatics tools. The knowledge on bioinformatics presented enables readers to go beyond a mere push-button approach to using bioinformatics software and interpreting the data generated, but also to assess the potential and limitations of today's bioinformatics software and future challenges.
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 Z730866Bioinformatics: Methods Express The book provides the clear advice and explicit protocols that non-bioinformaticians need in order to understand what to do - and how to avoid common pitfalls. Each chapter guides you through the major databases and tools with worked examples - all accompanied by sample data files available online.Topics covered include:*data access, *sequence searches and alignments, *identification and annotation of features, *the transcriptome, *protein structure and function, *comparisons and phylogeny. This book is a comprehensive manual for all wet-bench scientists who need to use bioinformatics - from postgraduate student to principal investigator.
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Z651923Bioinformatics: Sequence and Genome Analysis, 2nd Edition As more species’ genomes are sequenced, computational analysis of these data has become increasingly important. The second, entirely updated edition of this widely praised textbook provides a comprehensive and critical examination of the computational methods needed for analyzing DNA, RNA, and protein data, as well as genomes. The book has been rewritten to make it more accessible to a wider audience, including advanced undergraduate and graduate students. New features include chapter guides and explanatory information panels and glossary terms. New chapters in this second edition cover statistical analysis of sequence alignments, computer programming for bioinformatics, and data management and mining. Practically oriented problems at the ends of chapters enhance the value of the book as a teaching resource. The book also serves as an essential reference for professionals in molecular biology, pharmaceutical, and genome laboratories.
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B8161Bioinformatics: Sequence, Structure and Databanks, A Practical Approach Covers practical important topics in the analysis of protein sequences and structures. It compares amino acid sequences to structures comparing structures to each other, and presents searching information on entire protein families as well as searching with single sequences. It shows how to set up and use the SRS molecular biology database management system. There are chapters on multiple sequence alignment and protein secondary structure prediction.
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 BIO1Biokit: A��Journey to Life This text-and-puzzle-kit presents essential features of the "Central Dogma of Biochemistry"-replication, transcription, translation, the genetic code−using simple diagrams and analogies to everyday experience. The companion Biodisc, bound in each copy, includes a pair of super-imposable disks representing codons, etc.
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 Z350095Biological Data Analysis: A��Practical Approach This volume provides guidance for planning the correct strategy for a variety of different statistical approaches and modelling problems and interpreting the results. It describes how to analyze biological data, with commonly available software packages, without making errors which can invalidate results.
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 Z269670Biologically Active Peptides: Design, Synthesis, and Utilization Investigation into basic and advanced peptide design, synthesis, evaluation and utilization. New therapeutic approaches from experimental systems.
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B7183Biologist’s Guide to Analysis of DNA Microarray Data This is the first authoritative text to focus on microarray analysis (as opposed to technology) in diverse biological and medical applications. Written for biologists without special training in data analysis and statistics, the Guide takes over where the image analysis software that accompanies DNA array equipment typically leaves off-with a file of signal intensities and fold changes compared to a control. The broad spectrum of established analysis approaches is covered, including cluster analysis, function prediction, and principal component analysis. A thorough, critical review of software programs is presented.
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Z730343Biology of Cancer The Biology of Cancer synthesizes the findings of three decades of recent cancer research and proposes a conceptual framework from which to teach about these discoveries. It provides the necessary structure, organization, and content for a course on cancer biology for advanced undergraduates and beginning doctoral students. The book is comprehensive and offers many pedagogical features to assist teaching and learning. The text provides current information on topics such as tumor stem cells and recently introduced chemotherapeutics. State-of-the-art techniques are discussed throughout. Modern biomedical research is explored, helping readers to hone their analytical abilities and to assimilate and think clearly about complex biological processes.
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B4556Biology of Phosphoinositides This review of current lipid signaling research places emphasis on the integration of the use of lipid signals in signal transduction and membrane trafficking. The regulation of phospholipase C, phospholipase D, phosphoinositide-3-kinases, chloride channel conductance by inositol (3,4,5,6) tetraphosphate, and of cytoskeletal protein activity by inositol lipids are covered in depth. There is specific discussion of the PH and FYVE lipid domains that allow lipids to control the movement, location, and activation-state of membrane proteins.
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Z379565Bioluminescence Methods and Protocols: Methods in Molecular Biology, Vol.��102 A collection of methods for using luciferase and green fluorescent protein in analytical biochemistry, molecular toxicology, and cell-based assays. The contributors are those who have developed and perfected their methods. The wide variety of illustrative applications ranges from specific molecular titer to microbial detection and analysis. Other topics include the manipulation of the lux, luc, and gfp genes and construction of recombinant organisms. Cutting-edge techniques, detailed instructions, and diverse examples should make this book a standard reference.
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Z730432Biomaterials Science: An Introduction to Materials in Medicine, 2nd ed. The second edition provides the most up-to-date comprehensive review of all aspects of biomaterials science. It integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials.
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Z705012Biomaterials for Delivery and Targeting of Protein and Nucleic Acids This book introduces the principles of polymer science and chemistry, as well as the basic biology required for understanding how biomaterials can be used as drug-delivery vehicles. No book to date combines a discussion of high-tech biomaterials-based delivery of protein and nucleic acid drugs with the pharmaceutical or biocompatibility aspects. Featuring contributions from leading experts from around the world, this text discusses physiochemical parameters used for design, development, and evaluation of biotechnological dosage forms for delivery of proteins, peptides, oligonucleotides, and genes. The authors also present biological barriers to extravasation and cellular uptake of proteins and nucleic acids.
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Z703079Biomedical Applications of Proteomics The first book to provide an overview over applications of proteomics in the discovery of new diagnostic, prognostic and therapeutic targets. Examples of applications are presented for the most important diseases like heart and cardiovascular disorders, cancer, infectious diseases and diseases of the nervous system. Aspects of pharmatoxicology as well as bioinformatics are also included. Authors form the U.S., Europe and Australia contribute with their specific expertise.
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 Z288179Biomedical Frontiers of Fluorine Chemistry pricing
B8674Biomembrane Transport Considers recent advances in transport protein structure and function, along with established concepts. It distinguishes the similarities and differences in the mechanisms of action of transport proteins, and details the importance of biomembrane transport to regulation and interorgan nutrient flows and metabolism. Contains a classification scheme for all known transport proteins according to their functions and amino acid residue sequence similarities.
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 Z272272Biomolecular NMR Spectroscopy NMR spectroscopy is an important tool for the understanding of the structure and, ultimately, the function of biomolecules. This book explains the signficant features of biological NMR spectroscopy. It makes use of the classical vector method in explaining the bewildering array of pulse sequences available. The book covers two-dimensional, three-dimensional, and four-dimensional NMR, and their application to protein and DNA structure determination. A unique feature is the coverage of the biological aspects of solid-state NMR spectroscopy. The author provides many selected examples from the research literature, illustrating the applications of NMR spectroscopy to biological proteins. It includes multidimensional NMR spectroscopy as applied to proteins, enzymes, membranes, and DNA, and covers protein folding.
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 Z369985Bioorganic��Chemistry: Nucleic Acids This inaugural volume in a major new series focuses on nucleic acids from an organic chemical viewpoint. From the structure and function of DNA and RNA to chemical and enzymatic synthesis to alternative structures and structures of macromolecular complexes, this unique approach offers important insights into biology at the molecular level.
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 Z378305Bioseparation of Proteins: Unfolding/Folding and Validation A detailed critical review of literature on effectiveness, economics, and validation of bioseparation processes for drugs and other biological products. Key contents include: stability under various separation conditions case studies on methods development protein refolding and inactivation mechanisms. Coverage includes classical as well as modern bioseparation techniques.
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B4681Bioseparations Engineering: Principles, Practice and Economics Opportunities are growing to apply separation science to the production of therapeutic compounds, specialty biochemicals, functional food ingredients, environmentally friendly biocatalysts and new bioproducts from renewable sources. This book covers methods, theory and materials that reduce the science of bioseparations to practice in the lab or plant. Examples address purification of biomolecules ranging from recombinant proteins to gene therapy products, with footnotes detailing economics of the products. Topics cover isocratic and gradient chromatography; sedimentation, centrifugation and filtration; membrane system; and precipitation and crystallization.
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B7178Biotech Entrepreneur’s Glossary This glossary of terms is essential for anyone working in the biotechnology industry. Over 1600 terms covering accounting, auditing, advertising, biotechnology, business management, computers and the internet, human resources, business law, patents and patent law, quality assurance/control, marketing and sales. Appendices include abbreviations and acronyms, biotech recruiters, venture capital firms, and federal laws affecting biotech firms.
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Z701106Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs This book defines biotechnology from the perspective of pharmaceuticals. The first section focuses on the process of transforming a biologic macromolecule into a therapeutic agent, while the second section provides a brief overview of each class of macromolecule with respect to physiological role and clinical application. Additional detail is also provided in the second section for each FDA approved, recombinantly derived biopharmaceutical for each category of macromolecule. The final section looks to the future and the new advances that will enhance our ability to develop new macromolecules into effective biopharmaceuticals. This last section discusses various drug delivery strategies while also describing gene and cell therapy strategies.
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 Z286346Biotechnology for Improved Foods and Flavors Highlights the impact of biotechnology on the food industry and discusses strategies for producing new and improved raw materials. Details the latest analytical methodology for characterizing products generated by biotechnology. Describes the generation of flavors from precursors via enzymes and microorganisms. Discusses the construction of chimeric enzymes with improved properties. Reviews the effect of new plant crop regulators on crop yield and quality.
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 B5160Biotechnology from A��to��Z, 2nd ed. Fully updated to incorporate the most currently terminology, this second edition offers an illuminating and practical introduction to the ideas of biotechnology. From ADEPT to zoonosis, this book provides a concise and readable overview of the field. It explains the usefulness of many techniques in this fascinating and controversial industry.
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Z373680Biotechnology: A��Laboratory Course, 2nd��ed. this second edition consists of a series of laboratory exercises that integrate molecular biology with protein biochemistry. New exercises on PCR and western blotting have been added, as well as new procedures on large-scale plasmid isolation and DNA quantitation. The procedures and principles demonstrated are widely applicable in the biological sciences.
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Z423319Biotransformations in Organic Chemistry: A Textbook, 4th Ed. The use of biocatalysts, employed either as isolated enzymes or whole cells, offers a remarkable arsenal of highly selective transformations for modern preparative organic chemistry. During the last decade, this methodology has now generally been accepted as a complementary method to the already existing tools. After a basic introduction into the use of biocatalysts - principles of stereoselective transformations, kinetics, enzyme nomenclature and handling - the different types of reactions are explained according to the "reaction principle". The 4th edition includes new chapters on peroxidase reactions and on handling of biocatalysts.
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 Z731463Blood Banking and Transfusion Medicine: Basic Principles and Practice Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library.
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 Z422525Boron Chemistry at the Millennium This book grew out of a workshop held at the University of Georgia in May 1998, organized by Professor R.B. King. The results presented at this conference were divided into two categories: solid-state boron chemistry and boron compounds in organic synthesis. The papers, recently published in special issues of Inorganica Chimica Acta and the Journal of Organometallic Chemistry, are now available in this single book edition. Includes a supplement on boron reagents from Aldrich Chemical Company.
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Z704660Boronic Acids: Preparation and Application in Organic Synthesis and Medicine Dennis Hall covers all aspects of this important substance class. Starting with an introduction to the structure, properties, and preparation of boronic acid derivatives, together with an overview of their reactions and applications, the book goes on to look at metal-catalyzed borylation of alkanes and arenas, coupling reactions and rhodium-catalyzed additions of boronic acids to alkenes and carbonyl compounds. There follows chapters on copper-promoted C-O and C-N cross-coupling of boronic acids, applications in organic synthesis, as well as alpha-haloalkylboronic esters in asymmetric synthesis. Later sections deal with cycloadditions, organoboronic acids, oxazaborolidines as asymmetric inducers, and boronic acid based receptors and sensors. With experimental procedures, this book is invaluable reading for organic, catalytic and medicinal chemists, and those working in organometallics.
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Z730122Bretherick’s Handbook of Reactive Chemical Hazards, 7th ed. Bretherick’s Handbook of Reactive Chemical Hazards is widely regarded as the reference work in this field — an assembly of all reported risks such as explosion, fire, toxic or high-energy events that result from chemical reactions gone astray, with extensive referencing to the primary literature. It is designed to improve safety in laboratories that perform chemical synthesis and general research, as well as chemical manufacturing plants. Entries are ordered by empirical formula and indexed under both name(s) and Chemical Abstracts Registry Numbers. This two-volume compendium focuses on reactivity risks of chemicals, alone and in combination; toxicity hazards are only included for unexpected reactions giving volatile poisons.
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 Z251933Buckminsterfullerenes The world's leading experts have contributed their expertise to this book which presents the most current and comprehensive research on spheroidal carbon clusters (fullerenes) as well as discussing current problems and possible directions in future research.
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Z362166Buffer maker Windows® version Designs buffers using the Henderson-Hasselbalch equation. Has a library of over 500 buffer recipes! Also will calculate % constituent, ionic strength, dilution values, standardization values, pH, pK, and pKa.
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Z704105Bulk Crystal Growth of Electronic, Optical and Optoelectronic Materials A valuable, timely book for the crystal growth community, written by one of the most respected members in the field. The contents cover all the important materials from silicon through the III-V and II-IV compounds to oxides, nitrides, fluorides, carbides and diamonds. An international group of contributors from academia and industry provide a balanced treatment. The text includes global interest with particular relevance to: USA, Canada, UK, France, Germany, Netherlands, Belgium, Italy, Spain, Switzerland, Japan, Korea, Taiwan, China, Australia and South Africa
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Z701017Burger’s Medicinal Chemistry and Drug Discovery® 6th ed.,Volume 1: Drug Discovery This edition of Dr. Burger’s classic helps researchers with both traditional and state-of-the-art principles and practices governing new medicinal drug research and development. Completely revised to reflect the many changes that have occurred in the field, it brings together contributions by experts in a wide range of related fields to explore recent advances in the understanding of the structural biology of drug action, as well as cutting-edge technologies for drug discovery. This volume contains new chapters on Virtual Screening, Bioinformatics and Chemical Information Computing Systems in Drug Discovery.
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