ADME/Tox

Sigma-Aldrich provides an extensive range of products and services for ADME and Toxicology studies. This includes innovative genetically engineered cell lines and validated assays designed to improve drug metabolism, transporter, and safety testing, as well as reagents, consumables, and labware.

 

Permeability & Transporter Assays
For the prediction of permeability and transporter interactions of therapeutics.

Products

Caco-2 cell line models
HepaRG™ transporter KO
  cell line models

Kidney transporter KO cell line models
SOLVO® Membrane Vesicle
  Transporter Assays

LOPAC small molecule collections
Transwell plates


 

 

Toxicology Assays
For the prediction of toxicity of therapeutics.

Products
HepaRG™ 5F cell line model
Kidney SA7K cell line model
Cytotoxicity, Proliferation and
   Viability Reagents

iPSC-derived neural cell line models
idMOC plates




 

ADME/Tox Learning Center  
View additional resources including technology spotlights, technical bulletins, reviews, posters and publications.
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