Excipients for R&D Use Only

Excipients are materials used in the pharmaceutical industry that do not provide a pharmacological benefit but are used to improve the formulation or delivery of drug compounds. Because these materials are physically functional with minor or no biological activity, their characteristics can also be applied to diverse research problems. Excipients do not directly impact the metabolism of drug compounds in vivo and in vitro, but help to solubilize, form gels or suspensions, stabilize, or protect active substances. Some polymeric excipients are suitable for controlled release of active substances for extended dosage. The pharmaceutical industry uses excipients in the manufacture of tablets, capsules, solutions, and gels for medicinal applications. In life science research, excipients are primarily used to improve small molecule solubility, as matrix substances, and to stabilize and protect biomolecules from hostile environmental conditions.

Note: These products are for research and development use only. Not for manufacturing or uses requiring cGMP reagents. See Terms and Conditions of Sale for complete information.

Binders & Fillers

Binders are used as matrix-forming, stabilizing, and thickening agents. Some binders are suitable for use in sustained-release formulations of active substances.

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02286 Kollidon® 25 PVP Polyvidone Polyvinylpyrrolidone Povidone The Kollidon products consist of soluble and insoluble grades of polyvinylpyrrolidone (PVP) of various molecular weights and particle sizes. It is used as dry binders, film-formers, stabilizers in suspensions, dispersants for pigments, enzyme stabilisiers and bioavailablility improvers.
Kollidon SR is a blend of polyvinyl acetate and povidone (K 30) in the ratio 8:2 for use as matrix-forming agent. This research grade product is intended for use in R&D and development only.
79911 Kollidon® SR Polyvinyl acetate-Polyvinylpyrrolidone mixture Kollidon SR is a blend of polyvinyl acetate and povidone (K 30) in the ratio 8:2 used in the pharmaceutical industry as a matrix-forming agent. This research grade product is intended for use in R&D and development only.

Coatings

Coating substances help to protect biomolecules from environmental degradation and can control the release of the active ingredient component. Kollicoat® polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release, enteric, or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance.

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30549 Kollicoat® IR Macrogol-poly(vinyl alcohol) graft-copolymer Polyvinyl alcohol-polyethylene glycol graft-copolymer Kollicoat IR is used in the pharmaceutical industry as a binder, pellets, and particulate matter. This research grade product is intended for use in R&D and development only.
61354 Kollicoat® MAE 100 P 43.2-47.6% methacrylic acid basis (calc. on dried substance) Methacrylic acid-ethyl acrylate copolymer (1:1) Kollicoat MAE can be employed as film coatings (intelligent surfaces). Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.
Kollicoat® MAE 100 P has been used for the production of encapsulated recombinant cytokine (recombinant tumor necrosis factor α).
42385 Kollicoat® MAE 30 DP 46.0-50.6% methacrylic acid basis (calc. on solids content) Methacrylic acid copolymer dispersion Methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30 % Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.
39298 Kollicoat® Protect Polyvinyl alcohol-polyethylene glycol graft-copolymer and polyvinyl alcohol (PVA) Kollicoat Protect is a ready-to-use moisture barrier system for use in combination with pigments. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.
96329 Kollicoat® SR 30 D 28.5-31.5% solids basis Poly(vinyl acetate) dispersion 30 % Poly(vinyl acetate) stabilized with polyvinylpyrrolidone and sodium lauryl sulfate Kollicoat SR is use as a controlled-release coating or as a matrix. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.

Solubilizers & Emulsifiers

Solubilizers and emulsifiers are used to improve the solubilization of hydrophobic substances and to increase bioavailability. They are also used to stabilize suspensions and prepare colloids and gels.

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95921 Eumulgin® B25 ~100% active ingredients basis Macrogol (25)-cetostearyl ether Polyethylene glycol 1100 mono(hexadecyl/octadecyl) ether Eumulgin® B 25 is an oil-in-water emulsifier that is used for the production of ointments, creams, liquid emulsions, gels and other cosmetic formulations. It is supplied in the form of free-flowing, non-dusting micro-granules, and is an efficient protective colloid that can increase the stability of dispersed systems. This research grade product is intended for use in R&D only.
15759 Kolliphor® P 188 Lutrol® F68 Poloxamer 188 Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) Kolliphor P 188 has been widely used as a thickening agent and gel binder.
This research grade product is intended for use in R&D and development only.
78973 Kolliphor® P 188 micro Lμtrol® micro 68 Poloxamer 188, micronized Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) Lμtrol micro F68 has been widely used as a thickening agent and gel binder.
This research grade product is intended for use in R&D and development only.
62035 Kolliphor® P 407 oxyethylene 71.5-74.9 % Lutrol® F 127 Poloxamer 407 Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) Kolliphor P 407 has been widely used as a thickening agent and gel binder.
This research grade product is intended for use in R&D and development only.
50246 Kolliphor® P 407 micro Lμtrol® micro 127 Poloxamer 407, micronized Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) The Kolliphor P grades are poloxamers from the extensive line of Pluronic block copolymers. They are widely used as thinkening agent and gel binder.
This research grade product is intended for use in R&D and development only.
C5135 Kolliphor® EL pH-range 6.0 - 8.0 Cremophor® EL Macrogolglycerol ricinoleate PEG-35 castor oil Polyoxyl 35 hydrogenated castor oil Polyoxyl-35 castor oil Kolliphor® EL has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.
Used to emulsify and solubilize oils and other water-insoluble substances. Cremophor is the brand name for a range of non-ionic polyethoxylated detergents. It was originally developed for use as solubilizers and emulsifiers.
This research grade product is intended for use in R&D and development only.
30906 Kolliphor® ELP Cremophor® ELP PEG-35 castor oil Polyoxyl 35 Hydrogenated Castor oil Polyoxyl-35 castor oil Kolliphor is used to emulsify and solubilize oils and other water-insoluble substances. Similar to Kolliphor EL but with lower water content and differences in viscosity.
42966 Kolliphor® HS 15 Macrogol (15)-hydroxystearate Polyethylene glycol (15)-hydroxystearate Polyoxyethylated 12-hydroxystearic acid Solutol® HS 15 Non-ionic solubilizer and emulsifier.
This research grade product is intended for use in R&D and development only.
07076 Kolliphor® RH 40 Cremophor® RH 40 Macrogolglycerol hydroxystearate PEG-40 castor oil Polyoxyl 40 hydrogenated castor oil Kolliphor RH 40 is used to solubilize vitamins, water insoluble active substances and essential oils in water or mixtures of water and alcohol.
This research grade product is intended for use in R&D and development only.
91462 Kollisolv® PEG E 300 Lutrol® E 300 Macrogol 300 PEG Poly(ethylene glycol) Polyethylene glycol 300 Kollisolv polyethylene glycols are used as thickening agents and gel binders in the pharmaceutical industry.
This research grade product is intended for use in R&D and development only.
06855 Kollisolv® PEG E 400 Lutrol® E 400 Macrogol 400 PEG Poly(ethylene glycol) Polyethylene glycol 400 Kollisolv polyethylene glycols are used as thickening agents and gel binders in the pharmaceutical industry.
This research grade product is intended for use in R&D and development only.
16758 Poloxamer 407 purified, non-ionic Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) Do you have application information on this product that you would like to share?