Cyclooxygenase

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236005 COX-1 Inhibitor, FR122047 - CAS 130717-51-0 - Calbiochem The COX-1 Inhibitor, FR122047, also referenced under CAS 130717-51-0, controls the biological activity of COX-1. This small molecule/inhibitor is primarily used for Cell Signaling applications. C₂₃H₂₅N₃O₃S • HCl
236007 COX-1 Inhibitor IV, TFAP - CAS 1011244-68-0 - Calbiochem The COX-1 Inhibitor IV, TFAP, also referenced under CAS 1011244-68-0, controls the biological activity of COX-1. This small molecule/inhibitor is primarily used for Cell Signaling applications. C₁₃H₁₀F₃N₃O
236011 COX-2 Inhibitor I - CAS 416901-58-1 - Calbiochem The COX-2 Inhibitor I, also referenced under CAS 416901-58-1, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. C₁₈H₁₆ClNO₄S
236012 COX-2 Inhibitor II - CAS 181696-33-3 - Calbiochem The COX-2 Inhibitor II, also referenced under CAS 181696-33-3, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. C₁₆H₁₂F₂N₂O₃S
236013 COX-2 Inhibitor III - CAS 1177728-24-3 - Calbiochem The COX-2 Inhibitor III, also referenced under CAS 1177728-24-3, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. C₂₀H₂₁Cl₂N₃OS
236015 COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem The COX-2 Inhibitor V, FK3311, also referenced under CAS 116686-15-8, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. C₁₅H₁₃F₂NO₄S
239783 Cyclooxygenase Inhibitor Set - Calbiochem The Cyclooxygenase Inhibitor Set controls the biological activity of Cyclooxygenase. This small molecule/inhibitor is primarily used for Cell Signaling applications.  
239802 Curcumin, Curcuma longa L. - CAS 458-37-7 - Calbiochem A cell-permeable and irreversible antitumor and anti-inflammatory agent that acts as an inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (IC₅₀ = 52 µM). C₂₁H₂₀O₆
287840 Diclofenac Sodium - CAS 15307-79-6 - Calbiochem A cell-permeable, non-selective cyclooxygenase inhibitor (IC₅₀ = 60 nM and 200 nM for ovine COX-1 and COX-2 respectively) and potent non-steroidal anti-inflammatory drug with analgesic activity. C₁₄H₁₀Cl₂NO₂ · Na
344079-M Flurbiprofen - CAS 5104-49-4 - Calbiochem A mixture of S(+) and R(-) enantiomers. C₁₅H₁₃FO₂
349254 NS-398 - CAS 123653-11-2 - Calbiochem A cell-permeable selective inhibitor of COX-2 in vitro. C₁₃H₁₈N₂O₅S
401003 (±)-Ibuprofen - CAS 15687-27-1 - Calbiochem A nonsteroidal anti-inflammatory drug (NSAID) that acts as a reversible and competitive inhibitor of cyclooxygenase 1 (COX-1) (IC₅₀ = 4.85 µM). C₁₃H₁₈O₂
405268 Indomethacin - CAS 53-86-1 - Calbiochem A non-steroidal anti-inflammatory, cell permeable, antipyretic agent. C₁₉H₁₆ClNO₄
420345 Kaempferol - CAS 520-18-3 - Calbiochem A cell-permeable phytoestrogen that inhibits topoisomerase I-catalyzed DNA religation in HL-60 cells. C₁₅H₁₀O₆
434741 ETYA - CAS 1191-85-1 - Calbiochem Inhibits arachidonic acid uptake and the activities of arachidonic acid specific and non-specific acyl-CoA synthetases. C₂₀H₂₄O₂
444800 Meloxicam - CAS 71125-38-7 - Calbiochem A cell-permeable, non-steroidal anti-inflammatory drug (NSAID) of the oxicam family which preferentially inhibits the inducible isoform of COX-2 (IC₅₀ = 4.7 µM) relative to COX-1 (IC₅₀ = 36.6 µM). C₁₄H₁₃N₃O₄S₂
484100 5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem Potent Cl⁻ channel blocker (IC₅₀ = 100 nM-100 µM), depending on channel subtype and assay method. C₁₆H₁₆N₂O₄
523310 Pterostilbene, Pterocarpus marsupium - CAS 537-42-8 - Calbiochem A cell-permeable methoxylated analog of Resveratrol that displays antioxidant, antiproliferative, and hypoglycemic properties. C₁₆H₁₆O₃
553400 Radicicol, Diheterospora chlamydosporia - CAS 12772-57-5 - Calbiochem C₁₈H₁₇ClO₆
554325 Resveratrol - CAS 501-36-0 - Calbiochem A phenolic product found in both grape skins and wines. C₁₄H₁₂O₃
565610 SC-560 - CAS 188817-13-2 - Calbiochem A cell-permeable, highly potent and selective inhibitor of COX-1 (IC₅₀ = 9 nM). C₁₇H₁₂CIF₃N₂O
567305 SKF-86002 - CAS 72873-74-6 - Calbiochem A cell-permeable, reversible, and ATP-competitive cytokine-suppressive anti-inflammatory drug (CSAID). C₁₆H₁₂FN₃S
567630 Sodium Salicylate - CAS 54-21-7 - Calbiochem A cell-permeable, non-steroidal anti-inflammatory agent that interferes with TNF-induced NF-κB activation by inhibiting phosphorylation and subsequent degradation of the IκB-α protein. C₇H₅O₃ · Na
574102 Sulindac Sulfide - CAS 32004-67-4 - Calbiochem A cell-permeable, active metabolite of Sulindac. C₂₀H₁₇FO₂S
A1224 N-(4-Acetamidophenyl)indomethacinamide ≥98%, crystalline C27H24N3O4Cl
A5376 Acetylsalicylic acid ≥99.0% C9H8O4
A3537 5-Aminosalicylic acid ≥99% C7H7NO3
B7263 N-tert-Butyl-α-phenylnitrone ≥98% (GC) C11H15NO
D6899 Diclofenac sodium salt C14H10Cl2NNaO2
E1768 5,8,11,14-Eicosatetraynoic acid ≥97% C20H24O2
F0429 Flunixin meglumine ≥98% (HPLC) C14H11F3N2O2·C7H17NO5
F8514 Flurbiprofen cyclooxygenase inhibitor C15H13FO2
F7553 FR 122047 hydrochloride ≥98% (HPLC), powder C23H25N3O3SHCl
SMB00441 Geniposidic acid ≥98% (HPLC) C16H22O10
I4883 Ibuprofen ≥98% (GC) C13H18O2
I7378 Indomethacin ≥99% (TLC) C19H16ClNO4
I7904 Indomethacin heptyl ester methyl acetate solution, ≥98% (HPLC) C26H30ClNO4
K1751 Ketoprofen ≥98% (TLC) C16H14O3
K1136 Ketorolac tris salt ≥99%, crystalline C15H13NO3 · C4H11NO3
M3935 Meloxicam sodium salt hydrate ≥98% (HPLC) C14H12N3NaO4S2 · xH2O
M1275 Naproxen sodium 98.0-102.0% C14H13NaO3
N0630 Niflumic acid C13H9F3N2O2
N1016 Nimesulide C13H12N2O5S
N5023 Nordihydroguaiaretic acid ≥90% (HPLC), from Larrea divaricata (creosote bush) C18H22O4
N194 NS-398 ≥98% (HPLC), solid C13H18N2O5S
O5636 9,12-Octadecadiynoic acid ≥98% C18H28O2
O9637 Oxaprozin solid C18H15NO3
P8386 Phenylbutazone C19H20N2O2
P0740 N-(2-Phenylethyl)indomethacinamide C27H25N2O3Cl
P5654 Piroxicam ≥98% (TLC) C15H13N3O4S
P0865 N-(3-Pyridyl)indomethacinamide ≥98% C24H20N3O3Cl
R5010 Resveratrol ≥99% (HPLC) C14H12O3
S8139 Sulindac ≥98.0% C20H17FO3S
S3131 Sulindac sulfide ≥98% (HPLC), solid C20H17FO2S
V2889 Valeryl Salicylate ≥98% (HPLC) C12H14O4