Lipoxygenase

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205546 Caffeic Acid - CAS 331-39-5 - Calbiochem A natural dietary compound reported to have anti-carcinogenic and anti-inflammatory properties. C₉H₈O₄
239802 Curcumin, Curcuma longa L. - CAS 458-37-7 - Calbiochem A cell-permeable and irreversible antitumor and anti-inflammatory agent that acts as an inhibitor of 5-lipoxygenase (IC₅₀ = 8 µM) and cyclooxygenase (IC₅₀ = 52 µM). C₂₁H₂₀O₆
420600 Ketoconazole - CAS 65277-42-1 - Calbiochem An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. C₂₆H₂₈Cl₂N₄O₄
434741 ETYA - CAS 1191-85-1 - Calbiochem Inhibits arachidonic acid uptake and the activities of arachidonic acid specific and non-specific acyl-CoA synthetases. C₂₀H₂₄O₂
475889 MK-886 - CAS 118414-82-7 - Calbiochem A cell-permeable, orally active NSAID that blocks cellular Cox pathway PGE2 production by inhibiting COX-1 and mPGES-1, but not COX-2, activity, as well as suppresses cellular 5-LO pathway activation by inhibiting FLAP, rather than 5-LO, activity. C₂₇H₃₃ClNO₂S · Na
479975 NDGA - CAS 500-38-9 - Calbiochem A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC₅₀ = 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC₅₀ = 100 µM). C₁₈H₂₂O₄
557550 Ro106-9920 A cell-permeable tetrazolopyridazine-phenylsulfoxide compound that displays anti-inflammatory properties. C₁₀H₇N₅OS
567305 SKF-86002 - CAS 72873-74-6 - Calbiochem A cell-permeable, reversible, and ATP-competitive cytokine-suppressive anti-inflammatory drug (CSAID). C₁₆H₁₂FN₃S
D8008 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid ≥95% C22H40O2
E1768 5,8,11,14-Eicosatetraynoic acid ≥97% C20H24O2
N5023 Nordihydroguaiaretic acid ≥90% (HPLC), from Larrea divaricata (creosote bush) C18H22O4
O5636 9,12-Octadecadiynoic acid ≥98% C18H28O2