Topoisomerase I

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189400 Aurintricarboxylic Acid - CAS 4431-00-9 - Calbiochem A cell-permeable polyanionic, polyaromatic compound used as a powerful inhibitor of cellular processes that are dependent on the formation of protein-nucleic acid complexes. C₂₂H₁₄O₉
208925 Camptothecin, Camptotheca acuminata - CAS 2114454 - Calbiochem A cell-permeable DNA topoisomerase I inhibitor. C₂₀H₁₆N₂O₄
251800 Daunorubicin, Hydrochloride - CAS 23541-50-6 - Calbiochem Potent cell-permeable anticancer agent whose potential target site may be mitochondrial cytochrome c oxidase. C₂₇H₂₉NO₁₀ · HCl
324683 Ellagic Acid, Dihydrate - CAS 476-66-4 - Calbiochem A cell-permeable, reversible, potent antioxidant that has anti-mutagenic and anti-carcinogenic properties. C₁₄H₆O₈ · 2H₂O
324688 Ellipticine - CAS 519-23-3 - Calbiochem A cell-permeable antitumor alkaloid that acts as an inhibitor of topoisomerase II and acts as an intercalative agent that stimulates topoisomerase II-mediated DNA breakage. C₁₇H₁₄N₂
324905 Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem A cell-permeable antitumor antibiotic. C₂₇H₂₉NO₁₁ · HCl
341205 Etoposide - CAS 33419-42-0 - Calbiochem Etoposide, CAS 33419-42-0, is cell-permeable inhibitor of topoisomerase II inhibitor (IC50 = 59.2 µM). Displays anti-tumor activity., A cell-permeable derivative of podophyllotoxin that acts as a topoisomerase II inhibitor (IC₅₀ = 59.2 µM) has major activity against a number of tumors, including germ cell neoplasms, small cell lung cancer, and malignant lymphoma. C₂₉H₃₂O₁₃
390238 Camptothecin, 10-Hydroxy-, Camptotheca acuminata - CAS 64439-81-2 - Calbiochem A cell-permeable powerful DNA topoisomerase I inhibitor. C₂₀H₁₆N₂O₅
445800 Merbarone - CAS 97534-21-9 - Calbiochem A cell-permeable anticancer drug that inhibits the catalytic activity of topoisomerase II (topo II) without damaging DNA or stabilizing DNA-topo II cleavable complexes. C₁₁H₉N₃O₃S
574625 Suramin, Sodium Salt - CAS 129-46-4 - Calbiochem A reversible and competitive inhibitor of protein tyrosine phosphatases. C₅₁H₃₄N₆O₂₃S₆ . 6Na
614852 Topoisomerase IIα Inhibitor, TSC24 - Calbiochem The Topoisomerase IIα Inhibitor, TSC24 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications. C₁₃H₁₄N₄S
614853 Topoisomerase II Inhibitor, BNS-22 - Calbiochem The Topoisomerase II Inhibitor, BNS-22 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications. C₂₄H₂₅NO₅
A3145 Apigenin ≥97% (TLC), from parsley, powder C15H10O5
H0165 7-Ethyl-10-hydroxycamptothecin ≥98% (HPLC), powder C22H20N2O5
I1406 Irinotecan hydrochloride topoisomerase inhibitor C33H38N4O6 · HCl
K0133 Kaempferol ≥90% (HPLC), powder C15H10O6
L2037 β-Lapachone ≥98% (TLC) C15H14O3
L4045   Luotonin A ≥98% (HPLC)  
L5045   Luotonin B ≥98% C18H11N3O2
L4920   Luotonin E ≥98% C19H13N3O2
R4900 Rebeccamycin solid, ≥98% (HPLC), from Saccharothrix aerocolonigenes C27H21Cl2N3O7
R3655 Rubitecan C20H15N3O6