Cytochrome P450

Substrates

Phase I xenobiotic metabolism reactions are broadly grouped into three categories, oxidation, reduction, and hydrolysis. As most small molecule drugs are lipophilic in nature, drug metabolism converts these hydrophobic compounds into more water soluble compounds that can be excreted. Typically, oxidation is the most common phase I reaction. The hepatic cytochrome P450 system is the most important of the phase I oxidation systems.

Product #

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B5182 7-Benzyloxyquinoline ≥99% (HPLC), solid
B5057 7-Benzyloxy-4-trifluoromethylcoumarin ≥99% (HPLC), solid
D1306 Debrisoquine sulfate
E1379 7-Ethoxycoumarin
04141 7-Ethoxycoumarin-3-carbonitrile suitable for fluorescence, ≥99.0% (HPLC)
550485 3-Oxo-1-cyclopentanecarboxylic acid 97%
B1532 Resorufin benzyl ether CYP450 substrate
E3763 Resorufin ethyl ether
M1544 Resorufin methyl ether
P0928 Resorufin pentyl ether