Cathepsin L

Preferential cleavage:

Xaa = any amino acid residue
hydrophobic = Ala, Val, Leu, Ile, Phe, Trp, Tyr
aromatic = Phe, Trp, His, Tyr
↓ = cleavage site
 P6P5P4P3P2P1P1′P2′P3′P4′
 XaaXaaXaahydrophobicPheArgXaaXaaXaaXaa
 XaaXaaXaaaromaticPheArgXaaXaaXaaXaa
 XaaXaaXaahydrophobicArgArgXaaXaaXaaXaa
 XaaXaaXaaaromaticArgArgXaaXaaXaaXaa

Amino Acids Reference Chart

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Description

EC Number

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C6854 Cathepsin L from human liver ≥0.5 units/mg protein, solution 3.4.22.15  ( BRENDA | IUBMB )