Polylysine and Polyornithine Attachment Factors

Polyamino acids facilitate the attachment of cells and proteins to solid surfaces in biological applications. In cell cultures normal attachment, growth, and development of many cell types are dependent on attachment factors and extracellular matrix components. While some cells are able to synthesize these components, others require an exogenous source, particularly when grown in serum-free culture. To help facilitate attachment, cell spreading, growth, morphology, differentiation, and motility of your cells, Sigma offers a number of sterile, cell culture tested polyamino acids. In histochemical applications both polymers of D- and L-lysine are used to coat slides to promote attachment of cells. Poly-L-lysine has also been reported to improve protein coating of ELISA plates.

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P0296 Poly-D-lysine hydrobromide mol wt 1,000-5,000
P6403 Poly-D-lysine hydrobromide mol wt 4,000-15,000
P7886 Poly-D-lysine hydrobromide mol wt 30,000-70,000
P7280 Poly-D-lysine hydrobromide average mol wt 30,000-70,000, lyophilized powder, γ-irradiated, BioReagent, suitable for cell culture
P0899 Poly-D-lysine hydrobromide mol wt 70,000-150,000
P6407 Poly-D-lysine hydrobromide mol wt 70,000-150,000, lyophilized powder, γ-irradiated, BioReagent, suitable for cell culture
P1149 Poly-D-lysine hydrobromide mol wt 150,000-300,000
P1024 Poly-D-lysine hydrobromide mol wt ≥300,000
P7405 Poly-D-lysine hydrobromide mol wt >300,000, lyophilized powder, γ-irradiated, BioReagent, suitable for cell culture
P8954 Poly-L-lysine hydrobromide mol wt 500-2000
P0879 Poly-L-lysine hydrobromide mol wt 1,000-5,000
P6516 Poly-L-lysine hydrobromide mol wt 4,000-15,000 by viscosity Green Alternative
P7890 Poly-L-lysine hydrobromide mol wt 15,000-30,000 by viscosity
P2636 Poly-L-lysine hydrobromide mol wt 30,000-70,000
P9155 Poly-L-lysine hydrobromide mol wt 30,000-70,000, lyophilized powder, γ-irradiated, BioXtra, suitable for cell culture
P1274 Poly-L-lysine hydrobromide mol wt 70,000-150,000 by viscosity
P6282 Poly-L-lysine hydrobromide mol wt 70,000-150,000, lyophilized powder, γ-irradiated, BioXtra, suitable for cell culture
P1399 Poly-L-lysine hydrobromide mol wt 150,000-300,000
P1524 Poly-L-lysine hydrobromide mol wt ≥300,000
P5899 Poly-L-lysine hydrobromide mol wt ≥300,000, lyophilized powder, γ-irradiated, BioXtra, suitable for cell culture
P4707 Poly-L-lysine solution mol wt 70,000-150,000, 0.01%, sterile-filtered, BioReagent, suitable for cell culture
P4832 Poly-L-lysine solution mol wt 150,000-300,000, 0.01%, sterile-filtered, BioReagent, suitable for cell culture
P8920 Poly-L-lysine solution 0.1 % (w/v) in H2O
P4957 Poly-L-ornithine solution mol wt 30,000-70,000, 0.01%, sterile-filtered, BioReagent, suitable for cell culture