Antibodies to Glutamate Receptors

Glutamate is an amino acid that acts as a neurotransmitter in the Central Nervous System. It is associated with neural communication, memory formation, and learning. Glutamate receptors are also implicated in a number of neurodegenerative diseases. Exposure to toxins, old age, congenital predisposition, and brain trauma can trigger glutamate receptor activation and ensuing neurodegeneration. Ionotropic glutamate receptors form the ion channel pore that activates when glutamate binds to the receptor. There are also many subtypes of extracellular glutamate receptors that bind to some chemicals more selectively than to glutamate. Sigma-Aldrich offers monoclonal and polyclonal antibodies that act on glutamate receptors. They are reactive in human, rat, and other species, with various applications.

Product #

Description

Clone

Form

Gene Symbol (ID)

Species Reactivity

Application

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A4352 Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer831) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRIA1(2890)
rat ... Gria1(50592)
rat, human
ELISA (d), IHC, IP, WB
A4477 Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer845) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRIA1(2890)
rat ... Gria1(50592)
rat, human
DB, WB
G6642 Anti-Glutamate antibody produced in rabbit polyclonal
whole antiserum
  wide range
DB
G9282 Monoclonal Anti-Glutamate antibody produced in mouse GLU-4, monoclonal
ascites fluid
  wide range
ELISA (i)
G1545 Anti-Glutamate Receptor 3, Metabotropic antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRM3(2913)
mouse ... Grm3(108069)
rat ... Grm3(24416)
human
ICC, IHC (p), WB
G1670 Anti-Glutamate Receptor 4, Metabotropic antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRM4(2914)
mouse ... Grm4(268934)
rat ... Grm4(24417)
human
IHC (p)
G1795 Anti-Glutamate Receptor 6, Metabotropic antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRM6(2916)
mouse ... Grm6(108072)
rat ... Grm6(24419)
human
IHC (p)
G1920 Anti-Glutamate Receptor 7, Metabotropic antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRM7(2917)
mouse ... Grm7(108073)
rat ... Grm7(81672)
human
IHC (p)
G2045 Anti-Glutamate Receptor 8, Metabotropic antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRM8(2918)
mouse ... Grm8(14823)
rat ... Grm8(60590)
human
IHC (p)
G9665 Anti-Glutamate Receptor 1A, Metabotropic (mGluR1A) antibody produced in rabbit polyclonal
affinity isolated antibody
mouse ... Grm1(14816)
rat ... Grm1(24414)
rat, mouse, feline
IHC (f), WB
G9790 Anti-Glutamate Receptor 2/3, Metabotropic (mGluR2/3) antibody produced in rabbit polyclonal
affinity isolated antibody
mouse ... Grm2(108068)
rat ... Grm2(24415)
mouse, feline, rat
IF, IHC (f), IP, WB
G8913 Anti-Glutamate Receptor NMDAR1 (NR1) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRIN1(2902)
mouse ... Grin1(14810)
rat ... Grin1(24408)
mouse, rat, human
WB
G0166 Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C1) antibody produced in rabbit polyclonal
affinity isolated antibody
mouse ... Grin1(14810)
rat ... Grin1(24408)
rat, mouse
IHC (f), WB
G0541 Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert N1) antibody produced in rabbit polyclonal
affinity isolated antibody
rat ... Grin1(24408)
rat
DB, IHC, WB
G9038 Anti-Glutamate Receptor NMDAR2A (NR2A) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRIN2A(2903)
mouse ... Grin2a(14811)
rat ... Grin2a(24409)
human, rat, mouse
ARR, WB
M264 Anti-Glutamate Receptor NMDAR2A (NR2A) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRIN2A(2903)
mouse ... Grin2a(14811)
rat ... Grin2a(24409)
rat, human, mouse
IHC, IP, WB
M265 Anti-Glutamate Receptor NMDAR2B (NR2B) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRIN2B(2904)
mouse ... Grin2b(14812)
rat ... Grin2b(24410)
rat, mouse, human
IHC (f), IP, WB
M266 Anti-Glutamate Receptor NMDAR2C (NR2C) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRIN2C(2905)
mouse ... Grin2c(14813)
rat ... Grin2c(24411)
human, mouse, rat
IF, IHC (f), IP, WB
WH0002890M1 Monoclonal Anti-GRIA1 antibody produced in mouse 1G10, monoclonal
purified immunoglobulin
human ... GRIA1(2890)
human
ELISA (i), WB
SAB2100974 Anti-GRIN2A antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRIN2A(2903)
mouse, horse, human, guinea pig
WB
WH0002911M2 Monoclonal Anti-GRM1 antibody produced in mouse 1F7, monoclonal
purified immunoglobulin
human ... GRM1(2911)
human
ELISA (i), WB
AV32597 Anti-GRM6 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRM6(2916)
rabbit, rat, rabbit, mouse, canine, horse, guinea pig, human
WB
SAB2900137 Anti-GRM6 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRM6(2916)
human
IHC (p)
SAB2100976 Anti-GRM6 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRM6(2916)
rabbit, mouse, canine, guinea pig, horse, rat, rabbit, human, sheep
WB
WH0002916M1 Monoclonal Anti-GRM6 antibody produced in mouse 1A11, monoclonal
purified immunoglobulin
human ... GRM6(2916)
human
ELISA (i), WB
WH0002918M6 Monoclonal Anti-GRM8 antibody produced in mouse 4A7, monoclonal
purified immunoglobulin
human ... GRM8(2918)
human
ELISA (i), WB
M2442 Anti-phospho-N-Methyl D-Aspartate NR2B Subunit (pTyr1472) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRIN2B(2904)
mouse ... Grin2b(14812)
rat ... Grin2b(24410)
mouse, human, chicken, Xenopus, rat
ELISA (i), ICC, IP, WB
HPA015701 Anti-MGLUR1 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... GRM1(2911)
human
IHC
SAB2500699 Anti-NMDAR2B/GRIN2B antibody produced in goat polyclonal
affinity isolated antibody
human ... GRIN2B(2904)
human, rat, canine, mouse
ELISA (i), WB
SAB2500698 Anti-NMDA Receptor 1/GRIN1 antibody produced in goat polyclonal
affinity isolated antibody
human ... GRIN1(2902)
human, rat
ELISA (i), WB