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Antibodies to P2X Receptors

P2X receptors are cation-permeable ion channels in the cellular membrane that open in response to the binding of extracellular ATP and some related nucleotides. All P2X receptors (purinoceptors) are permeable to small monovalent cations, and some are permeable to calcium or anions. P2X receptors are found in neurons, glia, epithelia, endothelia, bone, and muscle cells. On smooth muscles, P2X receptors respond to ATP released from sympathetic motor nerves. On the sensory nerves in some organs, they are involved in sensing tissue damage and inflammatory stimuli. Activation of certain P2X receptor types by ATP appears to be an important factor in several pain states, and is therefore an important target for the treatment of inflammatory, visceral, and possibly also neuropathic pain. Sigma-Aldrich offers polyclonal P2X antibodies that have agonist and antagonist effects on the actions of purinergic receptors. They are reactive in human, rat, and other species, with various applications.

Product #

Description

Clone

Form

Gene Symbol (ID)

Species Reactivity

Application

Add to Cart

P7857 Anti-P2X1 Purinergic Receptor antibody produced in rabbit polyclonal
affinity isolated antibody
human ... P2RX1(5023)
mouse ... P2rx1(18436)
rat ... P2rx1(25505)
human, rat
IHC (p), WB CL
P7982 Anti-P2X2 Purinergic Receptor antibody produced in rabbit polyclonal
affinity isolated antibody
rat ... P2rx2(114115)
rat
IHC (p), WB CL
P8107 Anti-P2X4 Purinergic Receptor antibody produced in rabbit polyclonal
affinity isolated antibody
rat ... P2rx4(29659)
rat
IHC, WB CL
P8232 Anti-P2X7 Purinergic Receptor antibody produced in rabbit polyclonal
affinity isolated antibody
human ... P2RX7(5027)
mouse ... P2rx7(18439)
rat ... P2rx7(29665)
rat, mouse, human
WB
AV35105 Anti-P2RX1 antibody produced in rabbit polyclonal
IgG fraction of antiserum
human ... P2RX1(5023)
human, horse, bovine, rat, pig, mouse, canine, guinea pig, rabbit
IHC, WB
AV35518 Anti-P2RX7 antibody produced in rabbit polyclonal
IgG fraction of antiserum
human ... P2RX7(5027)
rat, guinea pig, human, mouse, canine, rabbit, bovine, horse
IHC, WB
SAB2101706 Anti-P2RX7 antibody produced in rabbit polyclonal
affinity isolated antibody
human ... P2RX7(5027)
pig, rat, bovine, canine, horse, human, mouse, rabbit
WB
P9247 Anti-Purinergic Receptor P2X5 antibody produced in rabbit polyclonal
affinity isolated antibody
mouse ... P2rx5(94045)
rat ... P2rx5(113995)
rat
WB
P4746 Anti-Purinergic Receptor P2X6 antibody produced in rabbit polyclonal
affinity isolated antibody
rat ... P2rx6(25041)
rat
WB
P9122 Anti-Purinergic Receptor P2X7 (extracellular) antibody produced in rabbit polyclonal
affinity isolated antibody
human ... P2RX7(5027)
mouse ... P2rx7(18439)
rat ... P2rx7(29665)
mouse, human, rat
WB
P8997 Anti-Purinergic Receptor P2X7 (extracellular)−FITC antibody produced in rabbit polyclonal
affinity isolated antibody
human ... P2RX7(5027)
mouse ... P2rx7(18439)
rat ... P2rx7(29665)
rat, human, mouse
FACS
P0120 Anti-Purinergic Receptor P2Y13 antibody produced in rabbit polyclonal
affinity isolated antibody
rat ... P2ry13(310444)
rat
WB