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IgY Antibodies

Sigma® Life Science offers a portfolio of IgY antibodies for use in common research applications such as immunofluorescence, immunohistochemistry, immunocytochemistry, Western blotting, flow cytometry, proteomic analysis studies and ELISA. There are many benefits to using an immunoglobulin Y antibody. In immunological studies, using immunoglobulin Y antibodies against a mammalian antigen produces less cross-reactivity and background than systems in which the antibody/antigen complex are both from mammalian sources. Moreover, the chicken immunoglobulin Y antibody demonstrates effective affinity to highly conserved regions across mammalian species.

Since chicken IgY antibodies are not recognized by Fc cell surface receptors, the use of immunoglobulin Y antibodies in cell surface protein detection, a common practice in flow cytometry, helps to minimize errant readings and high background. Additionally, our Seppro® protein deletion products use Immunoglobulin Y technology for the removal of highly abundant human plasma proteins making the remaining low abundant human proteins available for proteomic analysis of biomarkers.

Our IgY antibodies from chicken demonstrate species reactivity to a variety of human, mouse, rat, and plant antigens. We also offer immunoglobulin Y antibodies conjugated to peroxidase, alkaline phosphatase and fluorescent molecules. Each IgY antibody is covered by our Bioguarantee so that you can evaluate our antibodies with complete peace of mind.