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Bioactive Small Molecules Literature References
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Cell Biology Applications Center
Bioactive Small Molecules Literature References
Looking for current application references for Bioactive Small Molecules? Look no further!
Apoptosis Publications:
Click on the title to view the abstract on PubMed.
| Title |
Author / Journal |
Product Cited |
The retinoblastoma protein regulates pericentric heterochromatin.
|
Isaac, C.E., et al.
Mol Cell Biol, 2006; 3659-71. |
A0781 |
Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton.
|
Mayanagi, T., et al.
J Biol Chem, 2008; 31183-96. |
B0560 |
Epac and phospholipase Cepsilon regulate Ca2+ release in the heart by activation of protein kinase Cepsilon and calcium-calmodulin kinase II.
|
Oestreich, E.A., et al.
J Biol Chem, 2009; 1514-22. |
B0560 |
Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development.
|
Seifert, A.W., et al.
Development, 2008; 3949-57. |
C4116 |
Inhibition of oligodendrocyte apoptosis by sublytic C5b-9 is associated with enhanced synthesis of bcl-2 and mediated by inhibition of caspase-3 activation.
|
Soane, L., et al.
J Immunol, 2008; 6132-8. |
E1383 |
Effects of chemotherapeutic agents on the function of primary human osteoblast-like cells derived from children.
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Davies, J.H., et al.
J Clin Endocrinol Metab, 2003; 6088-97. |
E1383 |
Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta.
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Abbas, T., et al.
J Biol Chem, 2004; 9970-7. |
E1383 |
Effects of quercetin on the pharmacokinetics of Etoposide after oral or intravenous administration of etoposide in rats.
|
Li, X., et al.
Anticancer Res, 2009; 1411-5. |
E1383 |
Suppression of apoptosis in the protein kinase Cdelta null mouse in vivo.
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Humphries, M.J., et al.
J Biol Chem, 2005; 9728-37. |
A0781, E1383 |
Overexpression of Eg5 causes genomic instability and tumor formation in mice.
|
Castillo, A., et al.
Cancer Res, 2007; 10138-47. |
M8515 |
Mechanics of cell spreading: role of myosin II.
|
Wakatsuki, T., et al.
J Cell Sci, 2003; 1617-25. |
N6287 |
Epigenetic programming of the rRNA promoter by MBD3.
|
Brown, S.E., et al.
Mol Cell Biol, 2007; 4938-52. |
T8552 |
Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha.
|
Yan, J., et al.
Mol Endocrinol, 2007; 1630-41. |
T8552 |
A functional link between rhythmic changes in chromatin structure and the Arabidopsis biological clock.
|
Perales, M,., et al.
Plant Cell, 2005; 2111-23. |
T8552 |
Direct and indirect regulation of cytokine and cell cycle proteins by EBNA-2 during Epstein-Barr virus infection.
|
Spender, L.C., et al.
J Virol, 2001; 3537-46. |
T8552 |
14-3-3tau associates with and activates the MEF2D transcription factor during muscle cell differentiation.
|
Choi, S.J,., et al.
Nucleic Acids Res, 2001; 2836-42. |
T8552 |
Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures.
|
Marianna, P., et al.
Haematologica, 2001; 700-5. |
T8552 |
Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.
|
Zhang, Z.K., et al.
Mol Cell Biol, 2002; 5975-88. |
T8552 |
Concurrent opposite effects of trichostatin A, an inhibitor of histone deacetylases, on expression of alpha-MHC and cardiac tubulins: implication for gain in cardiac muscle contractility.
|
Davis, F.J., et al.
Am J Physiol Heart Circ Physiol, 2008; H1477-90. |
T8552 |
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils.
|
Condliffe, A.M., et al.
Blood, 2005; 1432-40. |
T8552 |
Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone.
|
Murphy, P.J., et al.
J Biol Chem, 2005; 33792-9. |
T8552 |
Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa.
|
Chang, C.W., et al.
Mol Cell Biol, 2005; 8401-14. |
T8552 |
Histone acetylation affects expression of cellular patterning genes in the Arabidopsis root epidermis.
|
Xu, C.R., et al.
Proc Natl Acad Sci U S A, 2005; 14469-74. |
T8552 |
Histone deacetylase inhibitor pharmacodynamic analysis by multiparameter flow cytometry.
|
Chung, E.J., et al.
Ann Clin Lab Sci, 2005; 397-406. |
T8552 |
Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance.
|
Kieffer, M., et al.
Plant Cell, 2006; 560-73. |
T8552 |
Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: potential clinical applications.
|
Guan, M., et al.
Clin Cancer Res, 2006; 1412-9. |
T8552 |
Functional interplay between histone demethylase and deacetylase enzymes.
|
Lee, M.G., et al.
Mol Cell Biol, 2006; 6395-402. |
T8552 |
Ketogenic HMGCS2 Is a c-Myc target gene expressed in differentiated cells of human colonic epithelium and down-regulated in colon cancer.
|
Camarero, N., et al.
Mol Cancer Res, 2006; 645-53. |
T8552 |
Mapping of the juxtacentromeric heterochromatin-euchromatin frontier of human chromosome 21.
|
Grunau, C., et al.
Genome Res, 2006; 1198-207. |
T8552 |
An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis.
|
Zhao, L.Y., et al.
Cancer Res, 2007; 9445-52. |
T8552 |
Site-specific acetylation of p53 directs selective transcription complex assembly.
|
Roy, S., et al.
J Biol Chem, 2007; 4765-71. |
T8552 |
Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing.
|
Shimazu, T., et al.
J Biol Chem, 2007; 4470-8. |
T8552 |
The telomerase reverse transcriptase (hTERT) gene is a direct target of the histone methyltransferase SMYD3.
|
Liu, C., et al.
Cancer Res, 2007; 2626-31. |
T8552 |
Beryllium induces premature senescence in human fibroblasts.
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Coates, S.S., et al.
J Pharmacol Exp Ther, 2009; J Pharmacol Exp Ther. |
T8552 |
BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3.
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Hishiki, T., et al.
J Biol Chem, 2007; 28335-43. |
T8552 |
Histone deacetylase inhibitors suppress TF-kappaB-dependent agonist-driven tissue factor expression in endothelial cells and monocytes.
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Wang, J., et al.
J Biol Chem, 2007; 28408-18. |
T8552 |
Regulation of aryl hydrocarbon receptor expression and function by glucocorticoids in mouse hepatoma cells.
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Bielefeld, K.A., et al.
Drug Metab Dispos, 2008; 543-51. |
T8552 |
Transcription of genes encoding synaptic vesicle proteins in human neural stem cells: chromatin accessibility, histone methylation pattern, and the essential role of rest.
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Ekici, M., et al.
J Biol Chem, 2008; 9257-68. |
T8552 |
HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity.
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Gupta, M.P., et al.
J Biol Chem, 2008; 10135-46. |
T8552 |
Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer.
|
Maruyama, R., et al.
Carcinogenesis, 2007; 1312-8. |
T8552 |
Multidrug resistance-associated protein-overexpressing teniposide-resistant human lymphomas undergo apoptosis by a tubulin-binding agent.
|
Aneja, R., et al.
Cancer Res, 2008; 1495-503. |
T8552 |
Recruitment to the nuclear periphery can alter expression of genes in human cells.
|
Finlan, L.E., et al.
PLoS Genet, 2009; e1000039. |
T8552 |
c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene.
|
Wolter, S., et al.
Mol Cell Biol, 2008; 4407-23. |
T8552 |
Histone acetylation is recruited in consolidation as a molecular feature of stronger memories.
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Federman, N., et al.
Learn Mem, 2009; 600-6. |
T8552 |
Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6.
|
Gibbs, A., et al.
Proc Natl Acad Sci U S A, 2009; 16663-8. |
T8552 |
Multifunctional role of Erk5 in multiple myeloma.
|
Carvajal-Vergara, X., et al.
Blood, 2006; 4492-9. |
V116 |
Netrin-1 is a survival factor during commissural neuron navigation.
|
Furne, C., et al.
Proc Natl Acad Sci U S A, 2008; 14465-70. |
V116 |
Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance.
|
Ho, J.D., et al.
Proc Natl Acad Sci U S A, 2008; 19383790. |
V116 |
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Kinase Phosphatase Biology Publications:
Click on the title to view the abstract on PubMed.
A Phosphatidylinositol 3-kinase-regulated Akt-independent signaling promotes cigarette smoke-induced FRA-1 expression.
|
Zhang, Q., et al.
J Biol Chem, 2006; 10174-81. |
G6416 |
Neuroprotection by histone deacetylase-related protein.
|
Morrison, B.E., et al.
Mol Cell Biol, 2006; 3550-64. |
G6416 |
HIV-1 latency in actively dividing human T cell lines.
|
Jeeninga, R.E., et al.
Retrovirology, 2008; 37. |
G6649 |
Angiotensin II type 2 receptor agonist directly inhibits proximal tubule sodium pump activity in obese but not in lean Zucker rats.
|
Hakam, A.C., et al.
Hypertension, 2008; 1117-24. |
K3761 |
Cyclooxygenase-2 up-regulates CCR7 via EP2/EP4 receptor signaling pathways to enhance lymphatic invasion of breast cancer cells.
|
Pan, M.R., et al.
J Biol Chem, 1999; 11155-63. |
K3761 |
Dedifferentiation of adult human myoblasts induced by ciliary neurotrophic factor in vitro.
|
Chen, X., et al.
Mol Biol Cell, 2005; 3140-51. |
P215 |
The Grb2/Mek pathway represses Nanog in murine embryonic stem cells.
|
Hamazaki, T., et al.
Mol Cell Biol, 1995; 7539-49. |
P215 |
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment.
|
Kunath, T., et al.
Development, 2006; 2895-902. |
P2499 |
Inhibition of glycogen synthase kinase-3beta is sufficient for airway smooth muscle hypertrophy.
|
Deng, H., et al.
J Biol Chem, 2008; 10198-207. |
S3442 |
Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance.
|
Wolf, A.M., et al.
J Neurosci, 2008; 3456-67. |
S3442 |
XIAP regulates cytosol-specific innate immunity to Listeria infection.
|
Bauler, L.D., et al.
PLoS Pathog, 2008; e1000142. |
S5567 |
A protein kinase Cepsilon-anti-apoptotic kinase signaling complex protects human vascular endothelial cells against apoptosis through induction of Bcl-2.
|
Steinberg, R., et al.
J Biol Chem, 2007; 32288-97. |
S5567, U120, S7067 |
Role of MAPK phosphatase-1 in sustained activation of JNK during ethanol-induced apoptosis in hepatocyte-like VL-17A cells.
|
Venugopal, S.K., et al.
J Biol Chem, 2007; 31900-8. |
S5567, U120, S7067 |
Structural inference of native and partially folded RNA by high-throughput contact mapping.
|
Das, R., et al.
Proc Natl Acad Sci U S A, 2008; 4144-9. |
S5567, U120, S7067 |
The role of RIP2 in p38 MAPK activation in the stressed heart.
|
Jacquet, S., et al.
J Biol Chem, 2008; 11964-71. |
S8307 |
TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype.
|
Sainson, R.C., et al.
Blood, 2008; 4997-5007. |
S8307 |
Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells.
|
Chen, L.Y., et al.
Am J Physiol Lung Cell Mol Physiol, 2008; L326-35. |
S8307 |
Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation.
|
Khimji, A.K., et al.
Am J Pathol, 2008; 716-27. |
S8307 |
Epigenetic programming of the rRNA promoter by MBD3.
|
Brown, S.E., et al.
Mol Cell Biol, 2007; 4938-52. |
S8307, P215 |
Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha.
|
Yan, J., et al.
Mol Endocrinol, 2007; 1630-41. |
S8307, P215 |
A functional link between rhythmic changes in chromatin structure and the Arabidopsis biological clock.
|
Perales, M,., et al.
Plant Cell, 2005; 2111-23. |
S8307, P215 |
Short-interfering RNA-mediated Lck knockdown results in augmented downstream T cell responses.
|
Methi, T., et al.
J Immunol, 2005; 7398-406. |
U120 |
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Neuroscience Publications:
Click on the title to view the abstract on PubMed.
A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis.
|
Sato, T., et al.
Proc Natl Acad Sci U S A, 2009; 1421-6. |
D5942 |
Local suppression of Epstein-Barr virus (EBV)-specific cytotoxicity in biopsies of EBV-positive Hodgkin's disease.
|
Frisan, T., et al.
Blood, 2008; 1493-501. |
F132 |
Platelet-derived growth factor and reactive oxygen species (ROS) regulate Ras protein levels in primary human fibroblasts via ERK1/2. Amplification of ROS and Ras in systemic sclerosis fibroblasts.
|
Svegliati, S., et al.
J Biol Chem, 2005; 36474-82. |
F132 |
Desvenlafaxine succinate: A new serotonin and norepinephrine reuptake inhibitor.
|
Deecher, D.C., et al.
J Pharmacol Exp Ther, 2006; 657-65. |
F132 |
Chronic fenfluramine administration increases plasma serotonin (5-hydroxytryptamine) to nontoxic levels.
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Zolkowska, D., et al.
J Pharmacol Exp Ther, 2006. |
F132 |
Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells.
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Accioly, MT., et al.
Cancer Res, 2008; 1732-40. |
F132 |
AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b.
|
Procino, G., et al.
J Cell Sci, 2008; 2097-106. |
F132 |
Influenza virus and poly(I:C) inhibit MHC class I-restricted presentation of cell-associated antigens derived from infected dead cells captured by human dendritic cells.
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Frleta, D., et al.
J Immunol, 2009; 2766-76. |
G154 |
Glycine inhibitory dysfunction induces a selectively dynamic, morphine-resistant, and neurokinin 1 receptor- independent mechanical allodynia.
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Miraucourt, LS., et al.
J Neurosci, 2005; 2519-27. |
G154 |
Na+/H+ exchange inhibition in hypertrophied myocardium subjected to cardioplegic arrest: an effective cardioprotective approach.
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Kevelaitis, E., et al.
Eur J Cardiothorac Surg, 2005; 111-6. |
H9523 |
The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics.
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Meredith, E.J., et al.
FASEB J, 2005; 1187-9. |
F132, H9523 |
Characterization of single channel currents from primary cilia of renal epithelial cells.
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Raychowdhury, M.K., et al.
J Biol Chem, 2007; 34718-22. |
F132, H9523 |
Intra-amygdaloid injection of kainic acid in rats with genetic absence epilepsy: the relationship of typical absence epilepsy and temporal lobe epilepsy.
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Gurbanova, A.A., et al.
J Neurosci, 2008; 7828-36. |
K0250 |
Sex differences in caspase activation after stroke.
|
Liu, F., et al.
Stroke, 2009; 1842-8. |
K0250 |
Global gene expression analysis reveals a role for the alpha 1 integrin in renal pathogenesis.
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Sampson, N.S., et al.
J Biol Chem, 2001; 34182-8. |
M0896 |
Intracellular Zn2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia.
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Medvedeva, Y.V., et al.
J Neurosci, 2009; 1105-14. |
M0896 |
Binding and crosslinking of 125I-labeled recombinant human tumor necrosis factor to cell surface receptors.
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Yoshie, O., et al.
J Biochem, 1986; 531-41. |
S180 |
Soluble expression of recombinant human secondary lymphoid chemokine (SLC) in E. coli and research on its in vitro and in vivo bioactivity.
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Chun, L., et al.
J Biochem, 2004; 769-76. |
S180 |
Cytosolic stress reduces degradation of connexin43 internalized from the cell surface and enhances gap junction formation and function.
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VanSlyke, J.K., et al.
Mol Biol Cell, 2005; 5247-57. |
S180 |
Electroporation-based methods for in vivo, whole mount and primary culture analysis of zebrafish brain development.
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Hendricks, M., et al.
Neural Dev, 2006; 6. |
S180 |
International Union of Pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and disease states.
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Jensen, R.T., et al.
Pharmacol Rev, 2005; 1-42. |
S180 |
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