Progranulin

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SRP6059 Progranulin from mouse recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)  
SRP6022 Progranulin human recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE), ≥90% (HPLC), FLAG-tagged  
SRP8014 Progranulin human recombinant, expressed in HEK 293 cells, untagged, >95% (SDS-PAGE) Progranulin (PGRN) is a widely expressed pluripotent growth factor, which plays a crucial role in various processes such as development, cell cycle progression, cell motility, wound repair and inflammation. Additionally, It is also implicated in early embryogenesis, host defense, cartilage development and degradation. Mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). PGRN expression is associated with the development of various type of cancer such as breast cancer, ovarian carcinoma, and multiple myeloma. Overexpression of PGRN has been observed in neurodegenerative diseases such as microglia of Creutzfeldt-Jacob patients and in spinal cord of amyotrophic lateral sclerosis (ALS) patients.
SRP8015 Progranulin mouse recombinant, expressed in HEK 293 cells, untagged, >95% (SDS-PAGE)  
SRP8016 Progranulin mouse recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE)  
SRP8017 Progranulin rat recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE)