High affinity for mammalian vasoactive intestinal peptide 2 (VIP2) receptor having equal potency and efficacy for stimulating cAMP production compared to mammalian vasoactive intestinal peptide (VIP) or pituitary adenylate cyclase activating polypeptide (PACAP).
Vasoactive Intestinal Peptide human, porcine, rat ≥95% (HPLC), powder
Neuropeptide that is widely distributed in the central and peripheral nervous systems. It is a vasodilator, bronchodilator and smooth muscle relaxant. It modulates the activity of many immune system cell types. It is a mitogen for embryonic sympathetic neurons. Its neuroprotective actions are mediated by the release of activity-dependent neurotrophic factors from glial cells.
Vasoactive Intestinal Peptide human, porcine, rat from synthetic, ≥95% (HPLC), powder
Neuropeptide that is widely distributed in the central and peripheral nervous systems. It is a vasodilator, bronchodilator and smooth muscle relaxant. It modulates the activity of many immune system cell types. It is a mitogen for embryonic sympathetic neurons. Its neuroprotective actions are mediated by the release of activity-dependent neurotrophic factors from glial cells.
VIP receptor antagonist. Blocks VIP neurotransmission in the exocrine pancreas, but does not block the effects of PACAP, which shares 68% homology with VIP. In contrast, it blocks both VIP- and PACAP-stimulated cyclic AMP accumulation in an osteoblast-like cell line.
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