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Stimulants

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Biochem/physiol Actions

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M200 (±)-N-Methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine hydrochloride solid Non-hallucinogenic; CNS stimulant. Analog of MDMA
H2O: soluble
F112 (+)-Fenfluramine hydrochloride (+)-Fenfluramine is a serotonin uptake inhibitor; anoxexic. (+)-Fenfluramine is neurotoxic on prolonged administration or at high dosage. (+)-Fenfluramine releases serotonin from axon terminals by a nonexocytotic mechanism.
H2O: soluble10 mg/mL
M8750 (+)-Methamphetamine hydrochloride Sympathomimetic with more potent central effects than amphetamine. It is transported into terminals via the monoamine transporters and induces release of dopamine, norepinephrine, epinephrine, and serotonin. Dopamine release is important for the addictive properties of methamphetamine while norepinephrine and epinephrine release are important for the cardiovascular effects. Serotonin neurotoxin.
H2O: soluble
ethanol: soluble
E2750 (+)-Pseudoephedrine hydrochloride ≥98% Non-selective adrenergic agonist; decongestant
 
M5037 2-(Methylamino)propiophenone hydrochloride Potent amphetamine-like stimulant; dimethylpropion metabolite.
 
A5880 D-Amphetamine hemisulfate salt Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake.
H2O: soluble
ethanol: soluble
M6935 L-threo-Methylphenidate hydrochloride solid Central nervous system stimulant. Less potent enantiomer.
H2O: soluble32 mg/mL
C222 Cathine hydrochloride Anorexic; with pharmacological effects similar to those of the amphetamines.
0.1 M HCl: soluble
H2O: soluble15 mg/mL, clear
ethanol: soluble
C8912 Cocaine free base Inhibits the dopamine, norepinephrine, and serotonin transporters with Kis of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.
 
C5776 Cocaine hydrochloride Inhibits the dopamine, norepinephrine, and serotonin transporters with Kis of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.
 
H1392 Harmaline hydrochloride dihydrate ≥95% CNS stimulant; may act through NMDA receptors
 
M2892 Methylphenidate hydrochloride CNS stimulant; releases catecholamines; potent inhibitor of dopamine reuptake
 
C3196 S(−)-Cathinone hydrochloride Alkaloid that is the major central nervous system stimulant of the Khat shrub. Like amphetamine, it is a potent releaser of norepinephrine and dopamine from their intracellular stores.
H2O: soluble
ethanol: soluble