Janus Kinase (JAK)

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420097 InSolution™ JAK Inhibitor I - CAS 457081-03-7 - Calbiochem InSolution™ JAK Inhibitor I, CAS 457081-03-7, is a 10 mM solution in DMSO. A highly potent, ATP-competitive inhibitor of JAK. (IC50 = 15, 1, 5 & 1 nM for JAK1, 2, 3 & Tyk2, respectively)., The InSolution™ JAK Inhibitor I, also referenced under CAS 457081-03-7, controls the biological activity of JAK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420099 JAK Inhibitor I - CAS 457081-03-7 - Calbiochem JAK Inhibitor I, CAS 457081-03-7, is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK 1 (IC₅₀ = 15 nM), JAK2 (IC₅₀ = 1 nM), JAK3 (Ki = 5 nM) and Tyk2 (IC₅₀ = 1 nM).
420101 JAK3 Inhibitor I - CAS 202475-60-3 - Calbiochem The JAK3 Inhibitor I, also referenced under CAS 202475-60-3, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420104 JAK3 Inhibitor II - CAS 211555-04-3 - Calbiochem The JAK3 Inhibitor II, also referenced under CAS 211555-04-3, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420112 JAK3 Inhibitor, Negative Control - CAS 153437-07-1 - Calbiochem The JAK3 Inhibitor, Negative Control, also referenced under CAS 153437-07-1, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420121 JAK3 Inhibitor IV - CAS 58753-54-1 - Calbiochem The JAK3 Inhibitor IV, also referenced under CAS 58753-54-1, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420122 JAK3 Inhibitor V - CAS 932258 - Calbiochem The JAK3 Inhibitor V, also referenced under CAS 932258, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420126 JAK3 Inhibitor VI - CAS 856436-16-3 - Calbiochem The JAK3 Inhibitor VI, also referenced under CAS 856436-16-3, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420132 JAK2 Inhibitor II - CAS 1837-91-8 - Calbiochem The JAK2 Inhibitor II, also referenced under CAS 1837-91-8, controls the biological activity of JAK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420139 JAK2 Inhibitor IV - CAS 1110502-30-1 - Calbiochem The JAK2 Inhibitor IV, also referenced under CAS 1110502-30-1, controls the biological activity of JAK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420141 JAK2 Inhibitor V, Z3 - CAS 195371-52-9 - Calbiochem The JAK2 Inhibitor V, Z3, also referenced under CAS 195371-52-9, controls the biological activity of JAK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420145 JAK3 Inhibitor VII, AD412 - CAS 796041-65-1 - Calbiochem The JAK3 Inhibitor VII, AD412, also referenced under CAS 796041-65-1, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420146 JAK3 Inhibitor VIII, NSC114792 - Calbiochem The JAK3 Inhibitor VIII, NSC114792 controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
420148 JAK3/GSK-3β/PKCα Inhibitor - CAS 1260181-14-3 - Calbiochem The JAK3/GSK-3β/PKCα Inhibitor, also referenced under CAS 1260181-14-3, controls the biological activity of JAK3/GSK-3β/PKCα. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
573098 JAK2 Inhibitor III, SD-1029 The JAK2 Inhibitor III, SD-1029, also referenced under CAS 118372-34-2, controls the biological activity of JAK2.
658408 AG 490, m-CF₃ - CAS 581797-29-7 - Calbiochem A cell-permeable, reversible, substrate competitive, m-trifluoromethyl derivative of AG 490 that displays apoptotic and antiproliferative properties.
SML1505 AZD1480 ≥98% (HPLC)
C8499 Cucurbitacin B hydrate ≥97% (HPLC)
C4493 Cucurbitacin I hydrate ≥95% (HPLC), solid
SML0455 1,2,3,4,5,6-Hexabromocyclohexane ≥98% (HPLC)
SRP0335 Jak1 active human recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)
SML0069 NSC 33994 ≥98% (HPLC)
PZ0304 PF-04965842 ≥98% (HPLC)
PZ0324 PF-06263276 ≥98% (HPLC)
PZ0316 PF-06651600 ≥98% (HPLC)
PZ0345 PF-06700841 tosylate salt ≥98% (HPLC)
PZ0017 Tofacitinib citrate ≥98% (HPLC)
T3434 Tyrphostin AG 490 solid
SML1024 WHI-P154 ≥98% (HPLC)
Z4626 ZM 39923 hydrochloride >98% (HPLC)