Caspase 3

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A0835 N-Acetyl-Asp-Glu-Val-Asp-al ≥95%, powder Reversible inhibitor of IL-1β converting enzyme (ICE); inhibits poly(ADP-ribose) polymerase cleavage by apopain (caspase 3).
A1341 N-Acetyl-Glu-Ser-Met-Asp-al ≥90% (HPLC), powder In the caspase-3 precursor, procaspase-3, the ESMD amino acid sequence has been identified as a cleavage site for producing the p17 and p12 subunits of mature caspase 3; Ac-ESMD-CHO has been shown to inhibit the protease that cleaves procaspase-3 at this site. Ac-ESMD-CHO binds caspase-7 and inhibits with a Ki of approximately 1300 nM, which makes it a weaker inhibitor than other inhibitor tetrapeptide analogs.
A1216 N-Acetyl-Ile-Glu-Thr-Asp-al ~99% (TLC), powder Caspase 8 inhibitor; blocks the cleavage of the 32 kDa caspase 3 precursor into the p12 and p20 subunits, thus blocking the formation of active caspase 3.
SCP0079 Caspase 2/3 Inhibitor ≥94% (HPLC)  
C0605 Z-Asp(O-Me)-Glu(O-Me)-Val-Asp(O-Me) fluoromethyl ketone ≥90% (HPLC) A cell-permeable inhibitor of caspase 3, 6, 7, 8, 10, which exhibits competitive and irreversible inhibition.
C0480 Z-Asp(OMe)-Gln-Met-Asp(OMe) fluoromethyl ketone powder A cell-permeable inhibitor of caspase 3 and 6, which exhibits competitive and irreversible inhibition.
V116 Z-VAD-FMK solid Non-selective, cell permeable inhibitor of caspase-1- and caspase-3-related proteases.