DFF45/ICAD human >85% (SDS-PAGE), solution, recombinant, expressed in Escherichia coli
DFF45 and DFF40 (also termed ICAD and CAD) are two subunits that make up the heterodimeric protein caspase-activated DNase or DNA fragmentation factor (DFF) that triggers DNA fragmentation during apoptosis.
Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. The 7-amido-4-trifluoromethylcoumarin derivative has better membrane permeability than the 7-amido-4-methylcoumarin derivative (A1086).
Fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.