Other Alzheimer’s Peptides

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M1063 Mca-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 fragment 667-675-(Dnp)Lys amide ≥96% (HPLC), solid  
G8291 Glu-Val-Asn-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyloctanoyl]-Ala-Glu-Phe >93% (HPLC), solid Inhibitor of brain β-secretase
H5536 Humanin solid Suppresses neuronal cell death in cells expressing amyloid precursor protein mutants related to familial Alzheimer′s disease.
H6161 [Gly14]-Humanin G human ≥97% (HPLC) Endogenous rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer′s disease genes and Aβ
M4564 7-Methoxycoumarin-4-acetyl-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-(2,4-dinitrophenyl)-Lys trifluoroacetate salt ≥90% (HPLC), lyophilized powder Fluorescent resonance energy transfer peptide for detecting α-secretase.
P2490 Presenilin-1 N-Terminal Peptide lyophilized powder Peptide used to study effects on the production of Aβ[X-42] peptide and accumulation of endogenous presenilin.
P2740 Presenilin-2 N-Terminal Peptide lyophilized powder Peptide used to study effects on the production of Aβ[X-42] peptide and accumulation of endogenous presenilin.
S4562 β-Secretase inhibitor ≥97% (HPLC), powder β-Site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) is a β-secretase that initiates the production of amyloid protein in Alzheimer′s dieases (AD) patients. β-Secretase inhibitors decrease the generation of β amyloid and formation of amyloid plaques typical of AD.
S2188 γ-Secretase inhibitor ≥90% (TLC), powder γ-Secretase activity is essential for the cleavage of β-amyloid precursor protein and the generation of amyloid β-peptide. γ-Secretase inhibitor are effective in preventing the accumulation of amyloid β-peptide in Alzheimer′s disease patients. It also inhibits the proteolytic processing of Notch protein and may be effective in treatment of colorectal neoplastic disease.