Protein Kinase Substrates

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A6583 Ala-Pro-Arg-Thr-Pro-Gly-Gly-Arg-Arg synthetic, lyophilized powder Substrate for meiosis-activated myelin basic protein kinase (p44mpk)
A6833 Arg-Lys-Arg-Ser-Arg-Ala-Glu lyophilized powder  
A0591 Autocamtide 2 trifluoroacetate salt ≥97% (HPLC)  
B1682 BAD from mouse ≥70% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution Bad, a pro-apoptotic factor, is a member of the Bcl-2 family. Cytokine-induced phosphorylation of Bad results in it being sequested in the cytosol. In the absence of cytokines such as interleukin 3 (IL-3), Bad dephosphorylation occurs, causing the release of cytochrome c from the mitochondria.
C5207 Calcineurin substrate ≥97% (HPLC) Peptide from the regulatory RII subunit of cAMP-dependent protein kinase. Useful in assays for protein phosphatase-2B (calcineurin) activity.
C4330 Casein Kinase II-β fragment 198-215 ≥95% (HPLC) Cdc2 substrate and competitive inhibitor of apoptosis. Sequence contains CK II autophosphorylation site plus p34cdc2 consensus phosphorylation site Ser209.
C2460 Casein Kinase II substrate ≥97% (HPLC) Selective substrate for Casein Kinase II.
C2335 Casein Kinase I substrate ≥95% (HPLC)  
C6110 Crebtide ≥98% (HPLC), lyophilized powder  
C6235 Crosstide ≥97% (HPLC), lyophilized powder Akt/PKBβ substrate.
C5859 c-Jun human 40-50% (SDS-PAGE), recombinant, expressed in E. coli, truncated human c-Jun sequence-GST fusion protein 1-169-GST, soluble Substrate for SAPK1/JNK2. Purified protein transcription factor which binds the AP1 gene to activate transcription.
C3233 c-Jun Kinase substrate from rat >90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution Highly specific substrate for JNK/SAPK.
L9905 Lys-Arg-Thr-Leu-Arg-Arg trifluoroacetate salt ≥97% (HPLC) Protein kinase C substrate derived from EGF receptor
M1891 Myelin Basic Protein bovine ≥90% (SDS-PAGE), lyophilized powder Major structural protein of CNS myelin
Mutation of the myelin basic protein gene induces dysmyelination; used to induce experimental allergic encephalomyelitis. Major structural protein of CNS myelin
Myelin basic protein (MBP) plays a vital role in formation of myelin sheath and is associated with the various neurological disorders. MBP functions as an antigenic target in autoimmune disease experimental allergic encephalomyelitis (EAE). MBP plays an essential role in cytoskeletal turnover and membrane extension. Additionally, it is also involved in Fyn-mediated signaling pathways, sequestration of phosphoinositides and regulation of calcium homoeostasis. MBP functions as an in vitro substrate for mitogen-activated protein kinase (MAP) kinase and aids in the purification and functional studies of enzyme.
P2186 [pGlu4]-Myelin basic protein fragment 4-14 ≥97% (HPLC) Specific substrate for protein kinase C.
M8184 Myelin Basic Protein Fragment 104-118 synthetic, lyophilized powder Substrate of Protein Kinase C
M2295 Myelin Basic Protein from guinea pig brain ≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain Mutation of the myelin basic protein gene induces dysmyelination; used to induce experimental allergic encephalomyelitis.
Myelin basic protein (MBP) plays a vital role in formation of myelin sheath and is associated with the various neurological disorders. MBP function as an antigenic target in autoimmune disease experimental allergic encephalomyelitis (EAE). MBP plays an essential role in cytoskeletal turnover and membrane extension. Additionally, it is also involved in Fyn-mediated signaling pathways, sequestration of phosphoinositides and regulation of calcium homoeostasis. MBP functions as an in vitro substrate for mitogen-activated protein kinase (MAP) kinase and aids in the purification and functional studies of enzyme.
M1816 Myelin Basic Protein Kinase 1 from bovine kidney >90% (SDS-PAGE)  
M1941 Myelin Basic Protein Kinase 2 from bovine kidney >90% (SDS-PAGE)  
L2275 Myosin Light Chain Kinase Fragment 11-19 amide ≥97% (HPLC) Myosin Light Chain Kinase (MLCK) Fragment 11-19 amide (Lys-Lys-Arg-Ala-Ala-Arg-Ala-Thr-Ser-NH2) is used as an inhibitor of Myosin Light Chain Kinase phosphorylation.
P0240 PRAK Substrate Peptide 1 mg/mL in H2O, ≥98% (HPLC), aqueous solution Peptide substrate for the enzyme PRAK (P38 regulated/activated protein kinase)