CRF

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A4933 Astressin ≥90% (HPLC) Highly potent CRF antagonist.
C2917 Corticotropin Releasing Factor Antagonist ≥97% (HPLC) The corticotropin releasing factor (CRF) antagonist α-helical CRF [9-41] exhibits 10-fold higher affinity for rat CRF receptors over human CRF receptors. It has been used to elucidate the role of CRF in various physiological systems. In colonic epithelium, it abolishes CRF-induced changes in ion secretion, and significantly inhibits CRF-stimulated conductance. It antagonizes the CRF-induced proinflammatory degranulation of perivascular mast cells that are activated in response to acute psychological stress and CRF secretion.
C2671 Corticotropin Releasing Factor bovine ≥90% (HPLC), Synthetic CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.
C0961 Corticotropin Releasing Factor Fragment 6-33 human, rat ≥97% (HPLC) CRF fragment that binds with high affinity to the CRF binding protein (CRF-BP) but has low affinity for the CRF receptor. Displaces CRF from CRF-BP.
C3042 Corticotropin Releasing Factor human, rat ≥95% (HPLC) CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.
C3167 Corticotropin Releasing Factor sheep ≥95% (HPLC) CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.
S3884 Sauvagine ≥97% (HPLC) A peptide related to CRF and urotensin 1 that was first isolated from the skin of the frog Phyllomedusa sauvagei. Potent releaser of ACTH and β-endorphin from the anterior pituitary.
C6426 Tyr-Corticotropin Releasing Factor Human, Rat ≥97% (HPLC)  
C0922 Tyr-Corticotropin Releasing Factor Ovine ≥97% (HPLC), Synthetic  
U4127 Urocortin human ≥85% (HPLC), powder Binds to CRF receptor types 1, 2α, and 2β; stimulates cAMP accumulation from cells transfected with these receptors. Acts in vitro to release ACTH from rat anterior pituitary cells.
Urocortin is a CRF-related neuropeptide having high affinity for CRF2 receptor possess appetite-suppressing effect. Urocortin along with corticotropin-releasing factor (CRF) binding protein (CRF-BP) enhances the free CRF levels in human brain by displacing hCRF from the binding protein.
U1008 Urocortin III human ≥97% (HPLC) Selective ligand with high affinity for CRF2 Receptors
Urocortin III belongs to corticotropin-releasing hormone family with high affinity for the type 2 corticotropin-releasing factor (CRFR2) receptor. It stimulates insulin and glucagon secretion.Urocortin III also possesses cardioprotective property and has minimal impact on the hypothalamic stress axis. It is, therefore, utilized for treating ischemic heart disease.
U9507 Urocortin II mouse Urocortin II is a CRF-related neuropeptide having high affinity for CRF2 receptor. It stimulates protein kinase A through CRF2 receptor and increases the contractility in rabbit ventricular myocytes. It also facilitates pro-inflammatory effects in human intestinal cells through corticotropin-releasing hormone receptor 2α.
corticotropin-releasing factor (CRF) peptide
U6631 Urocortin rat ≥97% (HPLC), powder Binds to CRF receptor types 1, 2α, and 2β; stimulates cAMP accumulation from cells transfected with these receptors. Acts in vitro to release ACTH from rat anterior pituitary cells.
Urocortin is a CRF-related neuropeptide that binds to CRF receptor types 1α, 2α and 2β. It possesses appetite-suppressing effect. Urocortin along with corticotropin-releasing factor (CRF) binding protein (CRF-BP) enhances the free CRF levels in human brain by displacing hCRF from the binding protein.
U8132 [pGlu110]-Prepro-Urotensin II Fragment 110-123 rat >98% (HPLC), solid Potent vasoconstrictor.
Rat Urotensin II is a neuroendocrine peptide that belongs to CRF family and possesses regionally-selective vasodilator impact on conscious rats. It also induces potent vasoconstriction in humans in vivo.
U7257 Urotensin II human ≥97% (HPLC), synthetic A neuroendocrine peptide of the CRF family that was originally isolated from fish brain but is also found in mammalian brain and spinal motor neurons. It is a potent vasoconstrictor. It may be a mediator of stress-induced anorexia.
Human urotensin II is a vasoactive neuropeptide that belongs to CRF family and stimulates arterial smooth muscle contraction, actin stress fiber formation and proliferation via small GTPase RhoA and there downstream effector Rho-kinase activation.The product is also a selective and potent vasoconstrictor agent as well as an agonist for the orphan receptor GPR14.
U7507 Urotensin II rat ≥97% (HPLC), synthetic A neuroendocrine peptide of the CRF family that was originally isolated from fish brain but is also found in mammalian brain and spinal motor neurons. It is a potent vasoconstrictor. It may be a mediator of stress-induced anorexia.
Rat Urotensin II is a neuroendocrine peptide that belongs to CRF family and possesses regionally-selective vasodilator impact on conscious rats. It also induces potent vasoconstriction in humans in vivo.
U7253 Urotensin I teleost fish ≥95% (HPLC) A neuroendocrine peptide of the CRF family that is found in the brain of most fish species. It may be involved in the regulation of blood pressure in fish. It is closely related to mammalian urocortin and releases ACTH from cultured rat pituitary cells.
Urotensin I is a CRF-like neuropeptide, expresses mainly in the brain of most fish species. It induces the acetylcholine (ACTH) release from the superfused goldfish anterior pituitary cell column. It stimulates the marked, dose-dependent reduction in perfusion pressure in the hind limb of the rat.