GH-RH

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G3902 Ghrelin human lyophilized powder Endogenous ligand to the orphan growth-hormone secretagogue receptor that stimulates the release of growth hormone from the pituitary.
G8903 Ghrelin rat lyophilized powder Endogenous ligand to the orphan growth-hormone secretagogue receptor that stimulates the release of growth hormone from the pituitary.
Ghrelin acts as a ligand for G-protein coupled receptor, GHS-R1A (growth hormone secretagogue receptor), and controls energy utilization and feeding. This peptide is involved in enhancing the value of rewarding foods, drugs and alcohol. In rats with diabetes, the expression of ghrelin increased as a result of cachexia. In rats with ovariectomy, the expression of this peptide decreased in the endometrium. This peptide controls cognitive functions and has neuroprotective roles in neurodegenerative disorders. In cultured cortical neuronal networks, ghrelin increases the rate of synapse formation and activity development.
G4535 [D-Lys3]-GHRP-6 synthetic, lyophilized powder [D-Lys3]-GHRP6 (growth hormone releasing peptide 6) induces the secretion of growth hormone (GH). In the membrane of clonal GC somatotropes, this peptide elevates the number of functional voltage-gated Ca2+ and Na+ channels. Chronic treatment with this peptide causes an elevation in Na+ macroscopic current in bovine pituitary somatotropes in culture, which results in an increase in the release of GH.
G6771 Growth Hormone Releasing Factor Fragment 1-29 amide human ≥97% (HPLC) GHRH/GRH (growth hormone releasing hormone) is released from the hypothalamus from where it reaches the anterior pituitary and binds to its receptor, thus, eventually leading to the release of GH (growth hormone) into the plasma.
G8770 Growth Hormone Releasing Factor Fragment 1-40 human ≥90% (HPLC) Equipotent to GRF (1-44) in stimulating release of somatotropin from anterior pituitary; endogenous peptide originally found in human pancreatic tumor cells, but also seen in hypothalamus
G8895 Growth Hormone Releasing Factor human ≥95% (HPLC), powder, synthetic Hypothalamic peptide that stimulates release of somatotropin from anterior pituitary
G6646 Growth Hormone Releasing Factor rat ≥95% (HPLC), powder, synthetic Hypothalamic peptide that stimulates release of somatotropin from anterior pituitary
SML1322 Ipamorelin acetate ≥98% Ipamorelin is a selective growth hormone secretagogue and agonist of the ghrelin receptor that selectively stimulates the ghrelin receptor and causes growth hormone release. The potency and efficacy of ipamorelin are similar to GHRP-6 but without increase plasma levels of ACTH or cortisol. Ipamorelin appears to enter the central nervous system and to activate GRLN receptors in the spinal cord.