LH-RH

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A8802 Antide ≥97% (HPLC) LH-RH antagonist with high anti-ovulatory and negligible histamine release activity.
B3303 Buserelin acetate salt ≥90% (HPLC) Buserelin is an LH-RH agonist.
L0399 Leuprolide acetate salt ≥98% (HPLC) Glp-His-Trp-Ser-Tyr-Leu-Leu-Arg-Pro-NHEt (des-Gly10-[D-Leu6]-LH-RH) is a GnRH (gonadotropin-releasing hormone) agonist, leuprolide. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Low concentration of leuprolide can be used for the treatment of endometriosis, uterine fibroids, central precocious puberty and advanced prostate cancer.
L1898 [D-Ala6]-LH-RH acetate salt hydrate ≥97% (HPLC) (D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
Potent LH-RH agonist.
L4913 [His(3-Methyl)2]-LH-RH >96% (HPLC) GnRH (gonadotropin-releasing hormone) (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
L4663 [D-Ser4]-LH-RH >97% (HPLC) GnRH (gonadotropin-releasing hormone) (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. GnRH peptides are used as agonists.
L9761 [D-Trp6]-LH-RH ≥97% (HPLC), powder Potent LH-RH agonist with enhanced biological activity due to its slower rate of degradation. Like [D-Lys6]-LH-RH, the D-Trp6 analog has been shown to be effective against cancers expressing the LH-RH receptor. However, unlike the D-Lys6 analog, it is generally used in the unconjugated form.
L4513 [des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate ≥97% (HPLC), powder Potent LH-RH agonist in rats and mice; reversibly delays sexual maturation in rats, stimulates spawning activity in fish. GnRH ( gonadotropin-releasing hormone, Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
L2761 [des-Gly10, D-His(Bzl)6]-LH-RH ethylamide ≥97% (HPLC), powder Glp-His-Trp-Ser-Tyr-His(Bzl)-Leu-Arg-Pro-NHEt ([des-Gly10, D-His(Bzl)6]-LH-RH) is a GnRH (gonadotropin-releasing hormone) agonist, histerelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Histerelin is used for the treatment of central precocious puberty in children. It inhibits actions of sex steroids on the male and female reproductive organs.
L4163 [des-Gly10, D-His2, D-Trp6, Pro9]-LH-RH ethylamide trifluoroacetate salt >98% (HPLC) Glp-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-NHEt ([des-Gly10, D-His2, D-Trp6, Pro9]-LH-RH) is a peptide from GnRH (gonadotropin-releasing hormone) agonists. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
L4038 [des-Gly10, D-Ser4, D-Trp6, Pro9]-LH-RH ethylamide trifluoroacetate salt >98% (HPLC) Glp-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-NHEt ([des-Gly10, D-Ser4, D-Trp6, Pro9]-LH-RH) is a peptide from GnRH (gonadotropin-releasing hormone) agonists. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
L3788 [des-Gly10, D-Tyr5, D-Trp6, Pro9]-LH-RH ethylamide trifluoroacetate salt >99% (HPLC) Glp-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-NHEt ([des-Gly10, D-Tyr5, D-Trp6, Pro9]-LH-RH) is a peptide from GnRH (gonadotropin-releasing hormone) agonists. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
L5413 Formyl-[D-Trp6]-LH-RH Fragment 2-10 >97% (HPLC) Formyl-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 (Formyl-[D-Trp6]-LH-RH Fragment 2-10) is a peptide from GnRH (gonadotropin-releasing hormone) agonist, triptorelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Application of triptorelin suppresses premature LH surge in IVF (in vitro fertilization). Additionally, triptorelin-mediated ovarian suppression in premenopausal women, undergoing chemotherapy for breast cancer, decreases chances of chemotherapy-associated early menopause.
L4538 [D-His(Bzl)6]-LH-RH Fragment 1-7 >96% (HPLC) Glp-His-Trp-Ser-Tyr-His(Bzl)-Leu ([D-His(Bzl)6]-LH-RH Fragment 1-7) is a peptide from GnRH (gonadotropin-releasing hormone) agonist, histerelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Histerelin is used for the treatment of central precocious puberty in children.
L5038 [D-Trp6]-LHRH Fragment, 1-6 >96% (HPLC)  
L3538 [D-His(benzyl)6]-LH-RH Fragment 3-9 ethylamide trifluoroacetate salt >99% (HPLC) Trp-Ser-Tyr-His(Bz)-Leu-Arg-Pro-NHEt ([D-His(benzyl)6]-LH-RH Fragment 3-9) is a peptide from GnRH (gonadotropin-releasing hormone) agonist, histerelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Histerelin is used for the treatment of central precocious puberty in children.
L3413 [D-His(Bzl)6]-LH-RH Fragment 4-9 ethylamide trifluoroacetate salt >95% (HPLC) Ser-Tyr-His(Bz)-Leu-Arg-Pro-NHEt ([D-His(Bzl)6]-LH-RH Fragment 4-9) is a peptide from GnRH (gonadotropin-releasing hormone) agonist, histerelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Histerelin is used for the treatment of central precocious puberty in children.
L3288 [D-His(Bzl)6]-LH-RH Fragment 5-9 Ethylamide trifluoroacetate salt >98% (HPLC) Tyr-His(Bz)-Leu-Arg-Pro-NHEt ([D-His(Bzl)6]-LH-RH Fragment 5-9) is a peptide from GnRH (gonadotropin-releasing hormone) agonist, histerelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Histerelin is used for the treatment of central precocious puberty in children.
L4788 [D-Trp6]-LH-RH-Leu-Arg-Pro-Gly-NH2 ≥96% (HPLC) Glp-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-Leu-Arg-Pro-Gly-NH2 ([D-Trp6]-LH-RH-Leu-Arg-Pro-Gly-NH2) is a GnRH (gonadotropin-releasing hormone) agonist, triptorelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Triptorelin is used for the treatment of hormone-associated prostate and breast cancers, endometriosis, uterine fibroids, central precocious puberty and in vitro fertilization.
L8008 Luteinizing hormone releasing hormone ≥97% (HPLC) Luteinizing hormone releasing hormone (LH-RH) is used to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary and to study many normal and pathological processes.
L3398 Luteinizing hormone releasing hormone Fragment 7-10 dihydrochloride ≥97% (HPLC)  
L7134 Luteinizing hormone releasing hormone human acetate salt ≥98% (HPLC), powder Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.
L4897 Luteinizing hormone releasing hormone salmon ≥97% (HPLC) Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.
M4505 Motilin porcine ≥97% (HPLC) Gastric motor stimulatory peptide. Inhibits the release of luteinizing hormone by central and peripheral administration.
SML0626 RFRP-3 human trifluoroacetate salt ≥98% (HPLC) RFRP-3 (RFamide-related peptide-3) is a homolog of avian gonadotropin-inhibitory hormone. RFRP-3 binds to the GPR147 receptor (also known as neuropeptide FF receptor 1). RFRP-3 blocks release of gonadotropin from the pituitary, and inhibits FSH-, LH- and forskolin-stimulated cAMP accumulation and progesterone production in human granulosa-lutein cells.
S3311 SDZ-216,887 SDZ-216,887 blocks the effects of endogenous Luteinizing hormone-releasing hormone (LH-RH) and inhibits the gene expression of pituitary LH-RH receptors.