Alanine hydroxymethyltransferase, D-

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C1159 L-Cycloserine Blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase. Cytotoxicity toward neuroblastoma and medulloblastoma cells mediated by suppression of ganglioside synthesis.
L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis.
C7005 DL-Cycloserine crystalline Inhibitor of alanine aminotransferase and other pyridoxal-phosphate-requiring transaminases; blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase.